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Differences in Injury Profiles Between Female and Male Athletes Across the Participant Classification Framework: A Systematic Review and Meta-Analysis
BackgroundFemale sex is a significant determinant of anterior cruciate ligament (ACL) injury. It is not understood if sex is a key determinant of...
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Associations between Participant Characteristics and Participant Feedback about an Unsupervised Online Cognitive Assessment in a Research Registry
BackgroundThis study aims to understand whether and how participant characteristics (age, gender, education, ethnocultural identity) are related to...
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Social Marketing Perspective on Participant Recruitment in Informatics-Based Intervention Studies
Effective recruitment strategies are pivotal for informatics-based intervention trials success, particularly for people living with HIV (PLWH), where...
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Use of Community Health Workers Among U.S. Male Latino Population: A Sco** Review
Community Health Workers (CHWs) are an effective strategy to address the health needs of specified communities. The purpose of this sco** review...
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Participant comprehension and acceptability of enhanced versus text-only electronic informed consent: an innovative qualitative pilot study
BackgroundThe use of electronic informed consent (eIC) in decentralized trials offers a pragmatic approach to enrolling participants across multiple...
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The development of theory-informed participant-centred interventions to maximise participant retention in randomised controlled trials
BackgroundA failure of clinical trials to retain participants can influence the trial findings and significantly impact the potential of the trial to...
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Ring-ing in the Future: Participant and Male Partner Perspectives Regarding Future Use of the Dapivirine Vaginal Ring for HIV Prevention
Women account for a disproportionate percentage of new HIV infections in sub-Saharan Africa indicating a need for female-initiated HIV prevention...
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Lifestyle and environmental risk factors for unexplained male infertility: study protocol for Australian Male Infertility Exposure (AMIE), a case–control study
BackgroundApproximately 1 in 20 men are sub-fertile or infertile yet the aetiologies of male infertility remain largely unexplained. It is suggested...
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Centring participant experience: a realist evaluation of a menstruator-friendly facility design project in a refugee settlement, Lebanon
IntroductionMenstrual health in humanitarian contexts is a neglected topic. Its taboo nature presents difficulties for participants in menstrual...
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Long-term participant retention and engagement patterns in an app and wearable-based multinational remote digital depression study
Recent growth in digital technologies has enabled the recruitment and monitoring of large and diverse populations in remote health studies. However,...
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Predictors of participant retention in a community-based HIV prevention cohort: perspectives from the HPTN 071 (PopART) study
IntroductionIn 2021, there were 38.4 million people living with HIV (PLHIV) globally, of which 20.6 million (54%) were living in Eastern and Southern...
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Factors Influencing the Hepcidin Response to Exercise: An Individual Participant Data Meta-analysis
BackgroundHepcidin, the master iron regulatory hormone, has been shown to peak 3–6 h postexercise, and is likely a major contributor to the...
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Integrating participant feedback and concerns to improve community and individual level chemical exposure assessment reports
BackgroundAs exposure assessment has shifted towards community-engaged research there has been an increasing trend towards reporting results to...
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How men influence young women taking PrEP: perspectives from young women, male partners, and male peers in Siaya county, Western Kenya
BackgroundDaily oral pre-exposure prophylaxis (PrEP) is an effective HIV prevention option for those who are most vulnerable to HIV infection,...
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Comparing body composition between the sweet-liking phenotypes: experimental data, systematic review and individual participant data meta-analysis
BackgroundLegislation aimed at reducing sugar intake assumes that sweet-liking drives overconsumption. However, evidence that a greater liking for...
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Pooled prevalence of depressive symptoms among medical students: an individual participant data meta-analysis
BackgroundThe methodological choice of aggregated estimates for meta-analysis may be notable for some common drawbacks, including variations in the...
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Opportunities and counterintuitive challenges for decentralized clinical trials to broaden participant inclusion
Traditional clinical trials have often failed to recruit representative participant populations. Just 5% of eligible patients participate in clinical...
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How do study design features and participant characteristics influence willingness to participate in clinical trials? Results from a choice experiment
BackgroundResearch about the decision to participate in a clinical study has tended to be limited to single indications and has focused on narrow...
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Influence of Participant Perceptions of Adherence-Related Interactions with Study/Study Team on Drug Levels: HPTN069 Analysis of Self-Reported Adherence Experiences While on Study
Adherence to HIV pre-exposure prophylaxis (PrEP) study drug is critical for safety, tolerability, and efficacy trials, and may be affected by how...
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Identifying relapse predictors in individual participant data with decision trees
BackgroundDepression is a highly common and recurrent condition. Predicting who is at most risk of relapse or recurrence can inform clinical...
