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The fully synthetic glycopeptide MAG-Tn3 therapeutic vaccine induces tumor-specific cytotoxic antibodies in breast cancer patients
Cancer is one of the main causes of mortality worldwide and a major public health concern. Among various strategies, therapeutic vaccines have been...
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Novel classes of immunotherapy for breast cancer
Immune-checkpoint inhibitors have profoundly changed the treatment landscape for many tumor types. Despite marked improvements in disease control for...
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Understanding Physico-chemical Interactions of Dendrimers with Guest Molecules for Efficient Drug and Gene Delivery
Purpose of ReviewDrug and gene deliveries are crucial aspects in biomedical application as they stimulate biological response of the body to elicit a...
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The fully synthetic MAG-Tn3 therapeutic vaccine containing the tetanus toxoid-derived TT830-844 universal epitope provides anti-tumor immunity
Malignant transformations are often associated with aberrant glycosylation processes that lead to the expression of new carbohydrate antigens at the...
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Monoclonal antibodies toward different Tn-amino acid backbones display distinct recognition patterns on human cancer cells. Implications for effective immuno-targeting of cancer
The Tn antigen (GalNAcα- O -Ser/Thr) is a well-established tumor-associated marker which represents a good target for the design of anti-tumor...
