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Lymphocyte apoptosis and its association with the inflammatory markers and disease severity in juvenile-onset systemic lupus erythematosus patients
BackgroundThe defective clearance of apoptotic bodies in juvenile-onset systemic lupus erythematosus (jSLE) potentially leads to the persistence of...
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CD4 T lymphocyte subsets display heterogeneous susceptibility to apoptosis induced by serum from patients with systemic lupus erythematosus
BackgroundSerum from systemic lupus erythematosus (SLE) patients has been shown to induce T-lymphocyte (TL) apoptosis. Given that different cells of...
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Platelet/lymphocyte, neutrophil/lymphocyte, and lymphocyte/monocyte ratios as biomarkers for rheumatoid arthritis: correlation with disease activity
BackgroundAssessment of disease activity in rheumatoid arthritis (RA) patients is essential for the adjustment of therapy. Inflammatory changes in...
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9-cis-retinoic acid signaling in Sertoli cells regulates their immunomodulatory function to control lymphocyte physiology and Treg differentiation
BackgroundTestis is an immune privileged organ, which prevents the immune response against sperm antigens and inflammation. Testicular cells...
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Prognostic Significance of Pre-Treatment Neutrophil–Lymphocyte Ratio and Platelet-Lymphocyte Ratio in Head and Neck Malignancies
IntroductionCarcinoma is the second most common cause of death worldwide. The neutrophil–lymphocyte ratio (NLR) and the platelet-lymphocyte ratio...
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Expression analysis of lymphocyte subsets and lymphocyte-to-monocyte ratio: reveling immunosuppression and chronic inflammation in breast cancer
ObjectiveTo explore the immune status and chronic inflammation of breast cancer patients, this study aims to analyze the diagnostic value of...
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Selection of Monocyte-to-Lymphocyte Ratio (MLR) or Lymphocyte-to-Monocyte Ratio (LMR) as Best Prognostic Tool in Heart Failure: a Systematic Review
Inflammatory biomarkers, including monocyte-to-lymphocyte ratio (MLR) and lymphocyte-to-monocyte ratio (LMR), are less investigated for prognosis...
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Elevated platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio in patients with polymyositis/dermatomyositis: a retrospective study
ObjectivesThis study aimed to examine the diagnostic and prognostic value of the platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte...
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Comparison of neutrophil to lymphocyte ratio, platelet to lymphocyte ratio, and C-reactive protein in predicting osteomyelitis in patients with diabetic foot ulcer
IntroductionNeutrophil/lymphocyte ratio (NLR) and platelet/ lymphocyte ratio (PLR) are readily available and inexpensive biomarkers that have...
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Platelet lymphocyte ratio, lymphocyte monocyte ratio, mean platelet volume, and neutrophil lymphocyte ratio in Behcet’s disease and their relation to disease activity
BackgroundBehcet’s disease (BD) does not have specific laboratory finding or pathological physical examination sign, and only few studies have...
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Comprehensive transcriptomic analysis shows disturbed calcium homeostasis and deregulation of T lymphocyte apoptosis in inclusion body myositis
ObjectiveInclusion body myositis (IBM) has an unclear molecular etiology exhibiting both characteristic inflammatory T-cell activity and...
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Rituximab may affect T lymphocyte subsets balance in primary membranous nephropathy
BackgroundThe aim of this study was to investigate the effects and significance of rituximab (RTX) on the levels of T lymphocyte subsets in patients...
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The association of lymphocyte with hypothyroidism in obstructive sleep apnea
PurposeObstructive sleep apnea (OSA) is a common sleep-breathing disorder. Numerous investigations have found a strong inherent relationship between...
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Male patients with primary Sjögren’s syndrome have unique clinical manifestations and circulating lymphocyte profiles
ObjectivesWe aimed to explore the relationship between clinical characteristics and circulating lymphocyte profiles in Chinese male patients with...
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Circulating lymphocyte subpopulations in patients with systemic lupus erythematosus and their correlation with disease activity
The aim of the present study was to evaluate the overall alterations of peripheral blood lymphocyte subsets in patients with systemic lupus...
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PD-1+ T lymphocyte proportions and hospitalized exacerbation of COPD: a prospective cohort study
ObjectiveTo evaluate the predictive value of PD-1 expression in T lymphocytes for rehospitalization due to acute exacerbations of COPD (AECOPD) in...
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Exploring the clinical application value of peripheral blood T lymphocyte subset in patients with asymptomatic omicron infection
ObjectiveTo investigate the clinical significance and value of peripheral blood T lymphocyte subset in patients with asymptomatic novel coronavirus...
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Neutrophil to lymphocyte ratio and platelet to lymphocyte ratio as prognostic predictors for delirium in critically ill patients: a systematic review and meta-analysis
IntroductionIn this systematic review and meta-analysis, we aim to analyze the current literature to evaluate neutrophil to lymphocyte ratio (NLR)...
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Neutrophil to lymphocyte ratio in odontogenic infection: a systematic review
BackgroundWe conducted this systematic review to compile the evidence for the role of neutrophil to lymphocyte ratio (NLR) in odontogenic infection...
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Investigation of fingolimod-induced lymphocyte sequestration on inflammatory response and neurological damages after cardiac arrest
BackgroundA sepsis-like syndrome is known to occur after cardiac arrest, leading to cerebral infiltration by white blood cells (WBC). We hypothesized...
