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Comparative Safety and Efficacy of Low/Moderate-Intensity Statin plus Ezetimibe Combination Therapy vs. High-Intensity Statin Monotherapy in Patients with Atherosclerotic Cardiovascular Disease: An Updated Meta-Analysis
AimStatin therapy is considered the gold standard for treating hypercholesterolemia. This updated meta-analysis aims to compare the efficacy and...
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A fragility index analysis of clinical trials evaluating low-intensity extracorporeal shockwave therapy for erectile dysfunction
Erectile dysfunction is a common sexual dysfunction that affects a significant proportion of men. Low-intensity extracorporeal shockwave therapy has...
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High-intensity laser therapy in low back pain management: a systematic review with meta-analysis
Low back pain (LBP) is a widespread health issue affecting people globally and is the second leading cause of missed workdays. High-intensity laser...
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Optimal treatment conditions for low-intensity pulsed ultrasound therapy for Alzheimer’s disease: applications from mice to humans
PurposeWe previously developed a novel therapy with low-intensity pulsed ultrasound (LIPUS) that ameliorates cognitive decline through upregulation...
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Treatment of prostatitis with low-intensity extracorporeal shockwave therapy (LI-ESWT)
BackgroundProstatitis is known as the inflammation of the prostate. The treatments of prostatitis are either pharmacological or non-pharmacological...
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Long-term effects of combination treatment comprising low-intensity extracorporeal shockwave therapy and tadalafil for patients with erectile dysfunction: a retrospective study
This study retrospectively examined the effects of low-intensity extracorporeal shockwave therapy and tadalafil on erectile dysfunction patients. 116...
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Low-intensity laser diode plus extracorporeal shock wave therapy: a new treatment strategy in the management of Peyronie’s disease
PurposeTo assess the clinical effectiveness of extra corporeal shockwave therapy (ESWT) administration compared with ESWT plus a low-intensity laser...
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A meta-analysis on the efficacy of low-intensity cognitive behavioural therapy for generalised anxiety disorder
BackgroundLow-intensity cognitive behavioural therapy (LICBT) has been recommended as a primary intervention in the tiered care for mild to moderate...
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Thirty-year outcomes of low-intensity anticoagulation for mechanical aortic valve
The long-term safety, efficacy, and outcomes of low-intensity anticoagulation for mechanical heart valves remain unclear. This study aimed to...
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Efficacy of pharmacological and non-pharmacological therapy on pain intensity and disability of older people with chronic nonspecific low back pain: a protocol for a network meta-analysis
BackgroundThe purpose of this network meta-analysis (NMA) is to investigate the efficacy of pharmacological and non-pharmacological therapy on pain...
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A Review of Laser Therapy and Low-Intensity Ultrasound for Chronic Pain States
Purpose of ReviewChronic pain management therapies have expanded quickly over the past decade. In particular, the use of laser therapy and ultrasound...
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Effectiveness of pharmacological and non-pharmacological therapy on pain intensity and disability in older people with chronic nonspecific low back pain: a systematic review with meta-analysis
Background and PurposeThe aim of the present systematic review was to investigate the effectiveness of pharmacological and non-pharmacological...
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Efficacy of low-intensity shockwave therapy with different tadalafil regimens in patients with PDE5 inhibitor-resistant erectile dysfunction: a retrospective cohort study
PurposeCurrently, there is a lack of research comparing tadalafil treatment protocols recommended during low-intensity shock wave therapy (LI-SWT)...
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Effects of low-intensity extracorporeal shock wave therapy on lipopolysaccharide cystitis in a rat model of interstitial cystitis/bladder pain syndrome
PurposeTo investigate the effect of low-intensity extracorporeal shock wave therapy (LiESWT) on lipopolysaccharide (LPS)-induced cystitis in an...
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Low-intensity mindfulness and cognitive–behavioral therapy for social anxiety: a pilot randomized controlled trial
BackgroundCognitive–behavioral therapy (CBT) effectively improves the clinical symptoms of social anxiety disorder. However, there are non-responders...
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Indirect assessment of low-intensity shockwave therapy’s energy density and pulse frequency for erectile dysfunction: a systematic review, bayesian network meta-analysis and meta-regression
Shockwaves are thought to activate regenerative and angiogenic pathways, providing a possible therapeutic benefit for patients with erectile...
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Effects of low-intensity exercise on contractile property of skeletal muscle and the number of motor neurons in diabetic rats
The mode of diabetes-induced muscle and motor neuron damage depends on the type of muscle and motor neuron. One of the purposes of exercise therapy...
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Low-intensity red-light therapy in slowing myopic progression and the rebound effect after its cessation in Chinese children: a randomized controlled trial
PurposeTo investigate the effect of low-intensity red-light (LRL) therapy on myopic control and the response after its cessation.
Methods ...
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How do we define high and low dose intensity of heart failure medications: a sco** review
BackgroundOlder adults with heart failure often experience adverse drug events with high doses of heart failure medications. Recognizing whether a...
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Moderate- to vigorous-intensity physical activities for hemophilia A patients during low-dose pharmacokinetic-guided extended half-life factor VIII prophylaxis
BackgroundLow-dose pharmacokinetic (PK)-guided extended half-life (EHL) factor VIII (FVIII) prophylaxis can reduce the bleeding risk in hemophilia A...
