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Hepatocellular carcinoma: tumor heterogeneity and recurrence after preoperative locoregional therapy
How locoregional therapy (LRT) may change tumor compositional and functional heterogeneity, consequently contributing to treatment resistance and...
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Long-term locoregional recurrence in patients treated for breast cancer
Background/PurposeLocoregional control in breast cancer is a fundamental part of treatment and determinant for survival outcomes. It has been...
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Peritoneal Cell-Free Tumor DNA is a Biomarker of Locoregional and Peritoneal Recurrence in Resected Pancreatic Ductal Adenocarcinomas
BackgroundRecurrence after curative-intent pancreatectomy for pancreatic ductal adenocarcinomas (PDAC) is quite frequent with locoregional and...
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Locoregional Recurrence of Esophageal Cancer Treated with Curative Intent Local Salvage Therapy: A Single Center Experience
PurposeLocoregional recurrence of esophageal carcinoma after neoadjuvant therapy and en bloc esophagectomy, although uncommon, is challenging to...
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Caveolin-1 genotypes as predictor for locoregional recurrence and contralateral disease in breast cancer
PurposeCaveolin-1 (CAV1) has been implicated in breast cancer oncogenesis and metastasis and may be a potential prognosticator, especially for...
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Treatment patterns and survival of patients with locoregional recurrence in early-stage NSCLC: a literature review of real-world evidence
Approximately 10–50% of patients treated for early-stage (I–III), resectable non-small cell lung cancer (eNSCLC) will develop locoregional...
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Evaluation of the performance of and interobserver agreement on postoperative baseline CT findings in the identification of locoregional recurrence in patients with pancreatic ductal adenocarcinoma
PurposeTo evaluate interobserver agreement on the findings of baseline contrast-enhanced multidetector computed tomography (CE-MDCT) performed at the...
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Prognosis of isolated locoregional recurrence after early breast cancer with immediate breast reconstruction surgery: a retrospective multi‑institutional study
BackgroundThe prognosis in patients with breast cancer with isolated locoregional recurrence (ILRR) without simultaneous distant metastases after...
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A prediction model for distant metastasis after isolated locoregional recurrence of breast cancer
PurposeThe impact of progesterone receptor (PR) status on the prognosis of breast cancer after isolated locoregional recurrence (ILRR) remains...
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Radiomics analysis for the prediction of locoregional recurrence of locally advanced oropharyngeal cancer and hypopharyngeal cancer
PurposeBy radiomic analysis of the postcontrast CT images, this study aimed to predict locoregional recurrence (LR) of locally advanced oropharyngeal...
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Breast-Conserving Therapy is Associated with Improved Survival Without an Increased Risk of Locoregional Recurrence Compared with Mastectomy in Both Clinically Node-Positive and Node-Negative Breast Cancer Patients
IntroductionRandomized trials demonstrated equivalent survival between breast-conserving surgery combined with radiotherapy (BCT) and mastectomy...
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Optimal imaging criteria and modality to determine Milan criteria for the prediction of post-transplant HCC recurrence after locoregional treatment
ObjectivesWe aimed to investigate the optimal radiologic method to determine Milan criteria (MC) for the prediction of recurrence in patients who...
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Racial Disparities in Locoregional Recurrence in Postmenopausal Patients with Stage I–III, Hormone Receptor-Positive Breast Cancer Enrolled in the NSABP B-42 Clinical Trial
BackgroundThere are limited data examining racial disparities in locoregional recurrence (LRR) among women with access to high-quality care. We aimed...
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Liver Imaging-Reporting and Data System treatment response algorithm predicts postsurgical recurrence in locoregional therapy–treated hepatocellular carcinoma
ObjectivesIn HCC, locoregional therapy (LRT) is performed as a bridging or downstaging treatment before curative surgery. The impact of the LI-RADS...
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Surgical Management of Locoregional Recurrence in Breast Cancer
Locoregional recurrences from breast cancer represent a heterogeneous group of disease that poses a therapeutic challenge and needs a...
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Effects of gross tumor volume and radiation dose on survival and locoregional recurrence in early-stage extranodal NK/T-cell lymphoma treated with intensity-modulated radiation therapy
PurposeTo investigate the prognostic value of gross tumor volume (GTV) in early-stage extranodal NK/T-cell lymphoma (ENKTCL) treated with...
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Positive bag lavage cytology during thoracoscopic surgery for lung cancer is a significant predictor of locoregional recurrence
ObjectivesAdvances in thoracoscopic surgery have made skin incisions smaller, but there are concerns about cancer cell contamination during sample...
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Pairwise machine learning-based automatic diagnostic platform utilizing CT images and clinical information for predicting radiotherapy locoregional recurrence in elderly esophageal cancer patients
ObjectiveTo investigate the feasibility and accuracy of predicting locoregional recurrence (LR) in elderly patients with esophageal squamous cell...
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Tumor response and survival outcomes of salvage concurrent chemoradiotherapy with three-dimensional conformal radiotherapy and 5-fluorouracil/platinum-based chemotherapy for postoperative locoregional recurrence of esophageal squamous cell carcinoma
BackgroundSalvage concurrent chemoradiotherapy is effective against locoregional recurrence after curative resection of esophageal squamous cell...
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Genetic Considerations in the Locoregional Management of Breast Cancer: a Review of Current Evidence
Purpose of ReviewBreast cancer is the most commonly diagnosed cancer and is the second leading cause of cancer death in women. Breast cancer...