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Grundlagen der Nierenpathologie für Pathologen – Teil 2
The evaluation of kidney biopsies for specific renal diseases or kidney transplant biopsies is mainly restricted to specialized centers. Lesions in...
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Akute und chronische Nierenerkrankungen in der Differenzialdiagnose einer akuten Nierenfunktionsstörung
BackgroundMany different etiological and morphological kidney diseases first become noticeable through acute kidney dysfunction (acute kidney injury,...
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Diagnostik und Therapie der Fokal-Segmentalen Glomerulosklerose – 2023
The histopathological term focal-segmental glomerulosclerosis comprises different pathogenic processes with the unifying features of a high...
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Was ist gesichert in der Therapie der chronischen Nierenerkrankung?
Chronic kidney disease (CKD) is defined as a relevant excretion of albumin into the urine or a reduction of the glomerular filtration rate (GFR) over...
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Diagnostik und Therapie der Minimal Change Glomerulopathie beim Erwachsenen – 2023
Minimal change disease is a glomerulopathy that clinically manifests as acute onset nephrotic syndrome. A diagnosis is made by renal biopsy, implying...
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Interstitielle Nephritis
Acute interstitial nephritis (AIN) is a rare, often underdiagnosed condition and a common cause of renal failure. Drugs are the leading cause. The...
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Früh beginnende Demenzen
BackgroundDue to the demographic change dementia is a common and dramatically increasing reason for medical presentations. In approximately 8% of...
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Diagnostik und Behandlung ausgesuchter akuter Arzneimittelvergiftungen mit hoher klinischer Relevanz
Acute drug poisoning due to accidental or self-damaging overdoses is responsible for 5–10% of emergency medical interventions in Germany. The...
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Lithium therapy in older patients with bipolar disorder
Lithium-induced chronic but potentially reversible changes to the kidney are polyuria and reduced urine concentrating ability. If symptoms persist...
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Steroid-resistentes nephrotisches Syndrom
Steroid-resistant nephrotic syndrome (SRNS), together with the histomorphological correlate focal segmental glomerulosclerosis (FSGS), is a leading...
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Nephrotisches Syndrom des Kindes- und Jugendalters
BackgroundDespite fulfilling the criteria for an orphan disease, idiopathic nephrotic syndrome (NS) in children is the most frequent glomerular...
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Pharmakotherapie bei Niereninsuffizienz
Essential for drug dose adjustment is the glomerular filtration rate (GFR) not the serum creatinine level. In acute disease, a loading dose must be...
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Säure-Basen-Störungen in der Schwangerschaft
Pregnancy is marked by numerous physiological changes. These can promote the occurrence or exacerbate existing acid-base disorders. An acid-base...
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Hyperkalzämie
Hypercalcemia is a common clinical problem. Normally, the blood serum calcium concentration is strictly regulated. Hypercalcemia results when the...
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Nephrotisches Syndrom
Minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS) are histopathologically defined podocytopathies which are clinically...
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Gibt es bei der Lithiumlangzeitbehandlung ein erhöhtes Risiko für Nierentumoren?
Lithium salts are the recommended first-line treatment (gold standard) in national and international treatment guidelines for acute and maintenance...