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Research-based findings on scope of liposome-based cosmeceuticals: an updated review
BackgroundCosmeceuticals are cosmetic products with biologically active components that have drug-like benefits. Cosmeceuticals are currently rapidly...
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Population pharmacokinetics and toxicity correlation analysis of free and liposome-encapsulated doxorubicin in Chinese patients with advanced breast cancer
PurposeThe objective of this study was to investigate the pharmacokinetic characteristics of pegylated liposomal doxorubicin (PLD) in Chinese female...
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Characterization of PDL1 enhanced siRNA/albumin liposome for effective therapeutic function in lung cancer
PurposeThe applications of liposomes are limited due to poor structural stability and short drug circulation time. This study aims to build an...
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Theoretical and in vivo experimental investigation of laser hyperthermia for vascular dermatology mediated by liposome@Au core–shell nanoparticles
The 1064 nm Nd:YAG laser shows a good prospect for the treatment of port-wine stain (PWS), but it is necessary to enhance the blood absorption to...
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Efficacy and safety of mitoxantrone hydrochloride liposome injection in Chinese patients with advanced breast cancer: a randomized, open-label, active-controlled, single-center, phase II clinical trial
Purpose. This trial aimed to evaluate the efficacy and safety of mitoxantrone hydrochloride liposome injection (Lipo-MIT) in advanced breast cancer...
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An effective treatment approach of liposomally encapsulated metformin in colon cancer
Metformin is a drug that is widely used in the treatment of type-2 diabetes and its anticarcinogenic effect has been detected in many studies since...
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Liposomal delivery of gene therapy for ovarian cancer: a systematic review
ObjectiveTo systematically identify and narratively synthesize the evidence surrounding liposomal delivery of gene therapy and the outcome for...
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Preparation and in vitro evaluation of BBG-250 loaded liposomal formulation for anticancer potential
BackgroundLiposome-mediated drug delivery systems have emerged as a promising avenue for enhancing cancer treatment strategies. This study aims to...
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Liposome-based targeting of dopamine to the brain: a novel approach for the treatment of Parkinson’s disease
Delivery of drugs into the brain is poor due to the blood brain barrier (BBB). This study describes the development of a novel liposome-based...
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A single robust stability-indicating RP-HPLC analytical tool for apigenin quantification in bulk powder and in nanoliposomes: a novel approach
BackgroundApigenin (4′, 5, 7-trihydroxyflavone), a flavonoid, is present usually in fruits and vegetables possessing numerous biological properties...
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Theranostics Based on Liposome: Looking Back and Forward
Liposome is one of the oldest yet most successful nanomedicine platforms. Doxil®, PEGylated liposome loaded with doxorubicin (DOX), was approved by...
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AKT1 regulates UHRF1 protein stability and promotes the resistance to abiraterone in prostate cancer
Oncogenic activation of PI3K/AKT signaling pathway, together with epigenetic aberrations are the characters of castration-resistant prostate cancer...
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In vivo and in vitro toxicity evaluation of liposome-encapsulated sirolimus
BackgroundTo evaluate the in vivo and in vitro toxicity of a new formulation of liposome-encapsulated sirolimus (LES).
MethodsIn vitro experiments...
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Tumor suppression effect of ultrasound-sensitive nanoparticles with focused ultrasound in a pancreas cancer xenograft model
BackgroundWe investigated the tumor suppression effect of an ultrasound-sensitive doxorubicin-loaded liposome-based nanoparticle, IMP301, to enhance...
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Liposomal stem cell extract formulation from Coffea canephora shows outstanding anti-inflammatory activity, increased tissue repair, neocollagenesis and neoangiogenesis
Coffea canephora plant stem cells can have bioactive compounds with tissue repairing and anti-inflammatory action. This study aimed to develop a...
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The effects of a hirudin/liposome complex on a diabetic nephropathy rat model
BackgroundHirudin, an extract from Hirudo spp. , is an anticoagulant used to treat a variety of renal diseases, including diabetic nephropathy (DN)....
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Advances in nano-immunotherapy for hematological malignancies
Hematological malignancies (HMs) encompass a diverse group of blood neoplasms with significant morbidity and mortality. Immunotherapy has emerged as...
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Multifunctional nanoparticle-mediated combining therapy for human diseases
Combining existing drug therapy is essential in develo** new therapeutic agents in disease prevention and treatment. In preclinical investigations,...
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Folate-modified liposomes mediate the co-delivery of cisplatin with miR-219a-5p for the targeted treatment of cisplatin-resistant lung cancer
Cisplatin (DDP) resistance, often leading to first-line chemotherapy failure in non-small cell lung cancer (NSCLC), poses a significant challenge....
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Understanding the charismatic potential of nanotechnology to treat skin carcinoma
Carcinoma is a condition that continues to pose a significant challenge, despite current medical advances. Skin carcinoma is the leading cause of...
