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Social Determinants of Health and Limitation of Life-Sustaining Therapy in Neurocritical Care: A CHoRUS Pilot Project
BackgroundSocial determinants of health (SDOH) have been linked to neurocritical care outcomes. We sought to examine the extent to which SDOH explain...
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Prevalence, reasons, and timing of decisions to withhold/withdraw life-sustaining therapy for out-of-hospital cardiac arrest patients with extracorporeal cardiopulmonary resuscitation
BackgroundExtracorporeal cardiopulmonary resuscitation (ECPR) is rapidly becoming a common treatment strategy for patients with refractory cardiac...
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Limitation of life sustaining measures in neurocritical care: sex, timing, and advance directive
BackgroundThe limitation of life sustaining treatments (LLST) causes ethical dilemmas even in patients faced with poor prognosis, which applies to...
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Limiting life-sustaining treatment for very old ICU patients: cultural challenges and diverse practices
BackgroundDecisions about life-sustaining therapy (LST) in the intensive care unit (ICU) depend on predictions of survival as well as the expected...
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Declining to Provide or Continue Requested Life-Sustaining Treatment: Experience With a Hospital Resolving Conflict Policy
In 2015, the major critical care societies issued guidelines outlining a procedural approach to resolving intractable conflict between healthcare...
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Characteristics and outcomes of patients with do-not-resuscitate and physician orders for life-sustaining treatment in a medical intensive care unit: a retrospective cohort study
BackgroundIn the intensive care unit (ICU), we may encounter patients who have completed a Do-Not-Resuscitate (DNR) or a Physician Orders to Stop...
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Physicians’ attitudes and experiences about withholding/withdrawing life-sustaining treatments in pediatrics: a systematic review of quantitative evidence
BackgroundOne of the most important and ethically challenging decisions made for children with life-limiting conditions is withholding/withdrawing...
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Predictors and outcomes of withholding and withdrawal of life-sustaining treatments in intensive care units in Singapore: a multicentre observational study
BackgroundClinical practice guidelines on limitation of life-sustaining treatments (LST) in the intensive care unit (ICU), in the form of withholding...
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Eleven-year retrospective study characterizing patients with severe brain damage and poor neurological prognosis -role of physicians’ attitude toward life-sustaining treatment
BackgroundSevere brain hemorrhage/infarction and cardiac arrest constitute the most critical situations leading to poor neurological prognosis....
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Hospital to Hospital Transfers of Cerebral Hemorrhage: Characteristics of Early Withdrawal of Life-Sustaining Treatment
BackgroundLarge intracerebral hemorrhages (ICHs) are associated with significant morbidity and mortality. Patient transfer to higher level centers is...
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Limitation of life-sustaining therapies in critically ill patients with COVID-19: a descriptive epidemiological investigation from the COVID-ICU study
BackgroundLimitations of life-sustaining therapies (LST) practices are frequent and vary among intensive care units (ICUs). However, scarce data were...
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Limitation of life-sustaining treatment and patient involvement in decision-making: a retrospective study of a Danish COVID-19 patient cohort
BackgroundThe coronavirus (COVID-19) pandemic and the risk of an extensive overload of the healthcare systems have elucidated the need to make...
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The role of clinical phenotypes in decisions to limit life-sustaining treatment for very old patients in the ICU
BackgroundLimiting life-sustaining treatment (LST) in the intensive care unit (ICU) by withholding or withdrawing interventional therapies is...
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Physician decision-making process about withholding/withdrawing life-sustaining treatments in paediatric patients: a systematic review of qualitative evidence
BackgroundWith paediatric patients, deciding whether to withhold/withdraw life-sustaining treatments (LST) at the end of life is difficult and...
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Changes in decision-making process for life-sustaining treatment in patients with advanced cancer after the life-sustaining treatment decisions-making act
BackgroundCancer is a leading cause of death in Korea. To protect the autonomy and dignity of terminally ill patients, the Life-Sustaining Treatment...
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Factors Associated with Early Withdrawal of Life-Sustaining Treatments After Out-of-Hospital Cardiac Arrest: A Subanalysis of a Randomized Trial of Prehospital Therapeutic Hypothermia
BackgroundThe objective of this study is to describe incidence and factors associated with early withdrawal of life-sustaining therapies based on...
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Gender differences in the intention to withhold life-sustaining treatments involving severe dementia for self and on behalf of parent or spouse
BackgroundFew studies have explored gender differences in the attitudes toward advanced care planning and the intention to withhold life-sustaining...
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Can primary palliative care education change life-sustaining treatment intensity of older adults at the end of life? A retrospective study
BackgroundPalliative care education has been carried out in some hospitals and palliative care has gradually developed in mainland China. However,...
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Predictors of Surrogate Decision Makers Selecting Life-Sustaining Therapy for Severe Acute Brain Injury Patients: An Analysis of US Population Survey Data
BackgroundPatients with a severe acute brain injury admitted to the intensive care unit often have a poor neurological prognosis. In these...