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Addressing bottlenecks in Lassa fever treatment: overcoming the ribavirin parenteral formulation challenge
Ribavirin ampoule formulation remains a major challenge in managing Lassa fever disease. Lassa fever is an endemic viral hemorrhagic fever in the...
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Analysing the association between perceived knowledge, and attitudes on Lassa Fever infections and mortality risk factors in lower Bambara Chiefdom
BackgroundLassa fever (LF) presents significant public health challenges in Sierra Leone, particularly in the Lower Bambara Chiefdom. This study aims...
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Spatio-temporal spread and evolution of Lassa virus in West Africa
BackgroundLassa fever is a hemorrhagic disease caused by Lassa virus (LASV), which has been classified by the World Health Organization as one of the...
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The deuce-ace of Lassa Fever, Ebola virus disease and COVID-19 simultaneous infections and epidemics in West Africa: clinical and public health implications
Globally, the prevailing COVID-19 pandemic has caused unprecedented clinical and public health concerns with increasing morbidity and mortality....
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Fatal case of newborn Lassa fever virus infection mimicking late onset neonatal sepsis: a case report from northern Nigeria
BackgroundLassa fever is a zoonotic viral infection endemic to the West Africa countries. It is highly fatal during pregnancy and as such reports of...
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Factors associated with delayed presentation to healthcare facilities for Lassa fever cases, Nigeria 2019: a retrospective cohort study
BackgroundLarge outbreaks of Lassa fever (LF) occur annually in Nigeria. The case fatality rate among hospitalised cases is ~ 20%. The antiviral drug...
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Viral Hemorrhagic Fevers in Pregnant Women and the Vaccine Landscape: Comparisons Between Yellow Fever, Ebola, and Lassa Fever
Purpose of ReviewAs research efforts have advanced to understand the pathophysiology of viral hemorrhagic fevers (VHF) and other epidemic viral...
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Epidemiological description of and response to a large yellow fever outbreak in Edo state Nigeria, September 2018 - January 2019
BackgroundEdo State Surveillance Unit observed the emergence of a disease with “no clear-cut-diagnosis”, which affected peri-urban Local Government...
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Research Progress of Fever with Thrombocytopenia Syndrome
Severe fever with thrombocytopenia syndrome (SFTS) is a new infectious disease first discovered in Ta-pieh Mountains in central China in 2009. It is...
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A systematic scorecard-based approach to site assessment in preparation for Lassa fever vaccine clinical trials in affected countries
BackgroundWe sought to develop and test an objective scorecard-based system for assessing and categorizing available research sites in Lassa...
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Emerging and Re-emerging Infections in Travellers
This book provides essential information on the epidemiology, diagnosis and management of common and some rare infections in travellers. It will...
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Infection pattern, case fatality rate and spread of Lassa virus in Nigeria
BackgroundLassa fever (LF) is a zoonotic infectious disease of public concern in Nigeria. The infection dynamics of the disease is not well...
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A proposed One Health approach to control yellow fever outbreaks in Uganda
Yellow Fever (YF) is an acute viral hemorrhagic disease. Uganda is located within the Africa YF belt. Between 2019 and 2022, the Ugandan Health...
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Clinical characteristics and aetiology of uveitis in a viral haemorrhagic fever zone
Background/ObjectivesStudies on uveitis in Sierra Leone were conducted prior to the Ebola Virus Disease epidemic of 2013–16, which was associated...
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Investigation of a cross-border case of Lassa fever in West Africa
BackgroundInfectious disease prevention and control strategies require a coordinated, transnational approach. To establish core capacities of the...
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Sensitivity and specificity of diagnostic tests for Lassa fever: a systematic review
BackgroundLassa fever virus has been enlisted as a priority pathogen of epidemic potential by the World Health organization Research and Development...
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Knowledge and risk perception towards Lassa fever infection among residents of affected communities in Ebonyi State, Nigeria: implications for risk communication
BackgroundLassa fever (LF) is an epidemic-prone zoonotic disease prevalent in Nigeria and Ebonyi State is a high burden area in Nigeria. Low risk...
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Lesson learned from the investigation and response of Lassa fever outbreak, Margibi County, Liberia, 2018: case report
BackgroundLassa fever (LF) is a viral hemorrhagic disease caused by the Lassa virus (LASV) and endemic in West African countries with an estimation...
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Projecting vaccine demand and impact for emerging zoonotic pathogens
BackgroundDespite large outbreaks in humans seeming improbable for a number of zoonotic pathogens, several pose a concern due to their...
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Epidemiology and Genomic characteristics of arenavirus in rodents from the southeast coast of P.R. China
BackgroundWenzhou virus (WENV), a member of the Mammarenavirus genus in the Arenaviridae family, has been detected in wild rodents from eight...