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Characterizing coma in large vessel occlusion stroke
BackgroundComa is an unresponsive state of disordered consciousness characterized by impaired arousal and awareness. The epidemiology and...
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Predictors of outcome in large vessel occlusion stroke patients with intravenous tirofiban treatment: a post hoc analysis of the RESCUE BT clinical trial
ObjectiveThe aim of this study was to investigate the factors influencing good outcomes in patients receiving only intravenous tirofiban with...
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What predicts large vessel occlusion in mild stroke patients?
Background and purposeMild acute ischemic stroke (AIS) patients with large vessel occlusion (LVO) may benefit from thrombolysis or thrombectomy...
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Frequency and predictors of poststroke epilepsy after mechanical thrombectomy for large vessel occlusion stroke: results from a multicenter cohort study
BackgroundPoststroke epilepsy (PSE) represents an important complication of stroke. Data regarding the frequency and predictors of PSE in patients...
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The value of cardiopulmonary comorbidity in patients with acute large vessel occlusion stroke undergoing endovascular thrombectomy: a retrospective, observational cohort study
BackgroundChronic lung and heart diseases are more likely to lead an intensive end point after stroke onset. We aimed to investigate characteristics...
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Large vessel occlusion detection by non-contrast CT using artificial ıntelligence
IntroductionComputer vision models have been used to diagnose some disorders using computer tomography (CT) and magnetic resonance (MR) images. In...
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One-year morbidity and mortality in patients treated with standard-dose and low-dose apixaban after acute large vessel occlusion stroke
Although low-dose direct oral anticoagulants (DOACs) are recommended for patients at high risk of bleeding complications, it remains unclear whether...
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Stroke with large vessel occlusion in the posterior circulation: IV thrombolysis plus thrombectomy versus IV thrombolysis alone
Efficacy and safety of mechanical thrombectomy (MT) for stroke with posterior circulation large vessel occlusion (LVO) is still under debate. We...
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Deep medullary vein damage correlates with small vessel disease in small vessel occlusion acute ischemic stroke
ObjectivesWe aim to investigate whether cerebral small vessel disease (cSVD) imaging markers correlate with deep medullary vein (DMV) damage in small...
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The Efficacy and Safety of Tirofiban Use in Endovascular Thrombectomy for Intravenous Thrombolysis Applicable Patients with Large Vessel Occlusion Stroke—a Post Hoc Analysis from the Direct-MT Trial
PurposeThe purpose of the study was to evaluate the efficacy and safety of tirofiban use in endovascular thrombectomy for intravenous thrombolysis...
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Meniscus Sign in Patients with Anterior Circulation Large Vessel Occlusion Stroke does not Predict Outcome
PurposeThe angiographic appearance of the occlusion site was suggested to influence outcomes of stroke patients with large vessel occlusion (LVO) who...
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Distinct Alterations in Oxygenation, Ion Composition and Acid-Base Balance in Cerebral Collaterals During Large-Vessel Occlusion Stroke
PurposeDisturbances of blood gas and ion homeostasis including regional hypoxia and massive sodium (Na + )/potassium (K + ) shifts are a hallmark of...
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Access to and application of recanalizing therapies for severe acute ischemic stroke caused by large vessel occlusion
BackgroundGroundbreaking study results since 2014 have dramatically changed the therapeutic options in acute therapy for severe ischemic stroke...
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Brain frailty associated with stroke events in anterior circulation large artery occlusion
ObjectiveTo investigate the factors associated with brain frailty and the effect of brain frailty in patients with anterior circulation large artery...
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Cost-effectiveness of CT perfusion for the detection of large vessel occlusion acute ischemic stroke followed by endovascular treatment: a model-based health economic evaluation study
ObjectivesCT perfusion (CTP) has been suggested to increase the rate of large vessel occlusion (LVO) detection in patients suspected of acute...
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Large-vessel-occlusion in patients with previous ischemic stroke: an analysis of adherence to secondary preventive medication for different etiologies
BackgroundLarge vessel occlusion (LVO) is a severe condition that carries a high risk of morbidity and mortality, underscoring the importance of...
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The clinical outcome of emergency superficial temporal artery-to-middle cerebral artery bypass in acute ischemic stroke with large vessel occlusion
The role of superficial temporal artery-to-middle cerebral artery (STA-MCA) bypass in acute ischemic stroke (AIS) is contentious, with no evidence in...
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Association between intravenous tirofiban and intracranial hemorrhage in acute large vessel occlusion stroke: insight from the RESCUE BT randomized placebo-controlled trial
BackgroundThe aim of this study is to investigate the association between intravenous tirofiban and symptomatic intracranial hemorrhage (SICH) in...
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Ticagrelor Versus Clopidogrel in Acute Large-Vessel Ischemic Stroke: A Randomized Controlled Single-Blinded Trial
BackgroundLarge-vessel ischemic stroke represents about 25–40% of all ischemic strokes. Few clinical trials compared ticagrelor versus clopidogrel in...
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Validation of a machine learning software tool for automated large vessel occlusion detection in patients with suspected acute stroke
PurposeCT angiography (CTA) is the imaging standard for large vessel occlusion (LVO) detection in patients with acute ischemic stroke. Stroke SENS ...