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Comparative evaluation of outcomes amongst different radiosurgery management paradigms for patients with large brain metastasis
IntroductionThis study compares four management paradigms for large brain metastasis (LMB): fractionated SRS (FSRS), staged SRS (SSRS), resection and...
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Immune related biomarkers for cancer metastasis to the brain
Brain metastasis accounts for a large number of cancer-related deaths. The host immune system, involved at each step of the metastatic cascade, plays...
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The impact of PET/CT and brain MRI for metastasis detection among patients with clinical T1-category lung cancer: Findings from a large-scale cohort study
Purpose[ 18 F]-FDG PET/CT and brain MRI are common approaches to detect metastasis in patients of lung cancer. Current guidelines for the use of...
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Natural history of spinal cord metastasis from brain glioblastomas
Background and ObjectivesSpinal cord metastasis arising from an intracranial glioblastoma is a rare and late event during the natural course of the...
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ITGB4 is a prognostic biomarker and correlated with lung adenocarcinoma brain metastasis
BackgroundThe aim of this study is to explore the prognostic value and immune signature of ITGB4 expression in lung adenocarcinoma (LUAD) brain...
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The relationship between brain metastasis and HER2 expression status in gastric cancer
BackgroundBrain metastasis (BM) in gastric cancer (GC) is underestimated, and human epidermal growth factor receptor 2 (HER2) overexpression is a...
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Systemic Treatment for Brain Metastasis and Leptomeningeal Disease in Breast Cancer Patients
Purpose of ReviewBreast cancer with brain metastasis (BCBM) and leptomeningeal disease (LMD) are important clinical problems. Traditionally, patients...
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Metastasis pattern and prognosis of large cell neuroendocrine carcinoma: a population-based study
PurposeAs a rare type of tumor, the metastasis pattern of large cell neuroendocrine carcinoma (LCNEC) is still unclear. Our aim was to investigate...
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Extracranial metastasis sites correlate to the incidence risk of brain metastasis in stage IV non-small cell lung cancer: a population-based study
PurposeThe aim of this study was to analyse the correlation of extracranial metastasis sites (ECMs) to the incidence risk of brain metastasis (BMs)...
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Brain metastasis in breast cancer: focus on genes and signaling pathways involved, blood–brain barrier and treatment strategies
Breast cancer (BC) is one of the most prevalent types of cancer in women. Despite advancement in early detection and efficient treatment, recurrence...
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Using machine learning-based radiomics to differentiate between glioma and solitary brain metastasis from lung cancer and its subtypes
ObjectiveTo establish a machine learning-based radiomics model to differentiate between glioma and solitary brain metastasis from lung cancer and its...
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Incidence of brain metastasis according to patient race and primary cancer origin: a systematic review
PurposeA systematic review was conducted to investigate differences in incidence and primary origin of synchronous brain metastasis (sBM) in varying...
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Screening and treatment of brain metastasis from papillary thyroid carcinoma: a case series
BackgroundThe brain metastasis from differentiated thyroid carcinoma (DTC) is a rare condition and its prognosis is poor. The standard protocol for...
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Deep learning-based metastasis detection in patients with lung cancer to enhance reproducibility and reduce workload in brain metastasis screening with MRI: a multi-center study
ObjectivesTo assess whether a deep learning-based system (DLS) with black-blood imaging for brain metastasis (BM) improves the diagnostic workflow in...
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Multiregional radiomics of brain metastasis can predict response to EGFR-TKI in metastatic NSCLC
ObjectivesTo develop radiomics signatures from multiparametric magnetic resonance imaging (MRI) scans to detect epidermal growth factor receptor...
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Incidence of Brain Metastasis as First Event in Patients with Esophageal Carcinoma: a Report from Three Prospective Alliance Clinical Trials
PurposeHistorically, reported incidence of brain metastasis secondary to esophageal carcinoma is low. We sought to determine the incidence of brain...
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Emerging Studies of Melanoma Brain Metastasis
Purpose of ReviewAmong solid tumors, melanoma has the highest propensity for brain dissemination. Although newer treatment approaches have resulted...
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Identifying Pathological Subtypes of Brain Metastasis from Lung Cancer Using MRI-Based Deep Learning Approach: A Multicenter Study
The aim of this study was to investigate the feasibility of deep learning (DL) based on multiparametric MRI to differentiate the pathological...
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Simultaneous evaluation of brain metastasis and thoracic cancer using semiconductor 11C-methionine PET/CT imaging
ObjectiveTo investigate the potential of whole-body digital 11 C-methionine (MET) PET/CT imaging for simultaneous evaluation of thoracic cancer...
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Up-front single-session radiosurgery for large brain metastases—volumetric responses and outcomes
BackgroundPatients presenting with large brain metastases (LBM) pose a management challenge to the multidisciplinary neuro-oncologic team. Treatment...
