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Development of castration resistance in prostate cancer patients treated with luteinizing hormone-releasing hormone analogues (LHRHa): results of the ANARESISTANCE study
PurposeEvaluate the percentage of patients with prostate cancer treated with luteinizing hormone-releasing hormone analogues (LHRHa) that develop...
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Subcapsular orchiectomy versus total orchiectomy and LHRH analogue in the treatment of hormone-sensitive metastatic prostate cancer: a different perspective in evaluation of the psychosocial effects
PurposeWe aimed to compare total orchiectomy, subcapsular orchiectomy, and luteinizing hormone-releasing hormone (LHRH) analogue treatment in...
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Incidence of hypertension in young transgender people after a 5-year follow-up: association with gender-affirming hormonal therapy
In order to assess the risk of hypertension development, we performed a retrospective analysis of the clinical records of consecutive transgender...
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Central precocious puberty secondary to postoperative craniopharyngioma: two case reports and a literature review
BackgroundCraniopharyngioma is a common intracranial tumour in children. Clinical manifestations are related to hypothalamic/pituitary deficiencies,...
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Systematic risk analysis of radiation pneumonitis in breast cancer: role of cotreatment with chemo-, endocrine, and targeted therapy
PurposeA major complication of sequential and concomitant chemoradiation in breast cancer treatment is interstitial pneumonitis induced by radiation...
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Development of a Novel Patient-Reported Outcome Measure to Assess Symptoms and Impacts of Androgen Deprivation Therapy for Advanced Prostate Cancer
IntroductionThis qualitative research study was conducted to develop a novel, comprehensive, patient-reported outcome measure (PRO), the “Symptoms...
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Long-term outcomes of high-risk HR-positive and HER2-negative early breast cancer patients from GEICAM adjuvant studies and El Álamo IV registry
PurposeThe monarchE trial showed that the addition of abemaciclib improves efficacy in patients with high-risk early breast cancer (EBC). We analyzed...
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PERSIAN trial (NCT05717660): an ongoing randomized trial testing androgen deprivation therapy, apalutamide and stereotactic body radiotherapy. An alternative “triplet” for oligometastatic hormone sensitive prostate cancer patients
Earlier treatment intensification with systemic potent androgen receptor inhibition has been shown to improve clinical outcomes in metastatic hormone...
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Impact of Systemic Therapy on Fertility in Women with Early-Stage Breast Cancer
Purpose of ReviewFertility concerns are common among young women diagnosed with breast cancer, as systemic therapy increases the risk of premature...
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Bone loss induced by cancer treatments in breast and prostate cancer patients
Cancer and cancer therapies are a major factor risk for osteoporosis due to bone loss and deterioration of bone microarchitecture. Both factors...
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The effect of unusual presentation on delayed diagnosis of prostate cancer: a case series
BackgroundEarly diagnosis of prostate cancer is key to achieving a cure and its proper management leads to a good prognosis. In Ghana a large...
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A multicentre randomised controlled trial of a guided self-help cognitive behavioural therapy to MANage the impact of hot flushes and night sweats in patients with prostate CANcer undergoing androgen deprivation therapy (MANCAN2)
BackgroundAndrogen deprivation therapy (ADT) is prescribed to almost half of all men diagnosed with prostate cancer. Although ADT is effective...
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Progression-free survival on endocrine therapy, before or after chemotherapy, in hormone receptor-positive HER2-negative metastatic breast cancer
PurposeA major question when treating HR+/HER2− metastatic breast cancer (MBC) is whether early introduction of chemotherapy (CT) increases endocrine...
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Triple-arm androgen blockade for advanced prostate cancer: a review
Prostate cancer is estimated to be the second most common malignancy in men in the USA in 2020 and represents the second highest mortality from...
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The effects of the covid-19 pandemic on puberty: a cross-sectional, multicenter study from Turkey
BackgroundsDuring the Coronavirus-19 disease (Covid-19) pandemic it was observed that the number of girls presenting with early puberty had...
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SEOM-GEICAM-SOLTI clinical guidelines for early-stage breast cancer (2022)
Breast cancer is the leading cause of cancer in women in Spain and its annual incidence is rapidly increasing. Thanks to the screening programs in...
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Central precocious puberty secondary to peripheral precocious puberty due to a pineal germ cell tumor: a case and review of literature
BackgroundThe pineal lesion affecting melatonin is a rare cause of central precocious puberty by decreasing the inhibition of...
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Postmyomectomy uterocutaneous fistula: a case report and literature review
BackgroundUterocutaneous fistula (UCF) is an uncommon clinical entity. The aetiology and optimal treatment strategy of UCF are still not clear. GnRHa...
