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Real world evaluation of kidney failure risk equations in predicting progression from chronic kidney disease to kidney failure in an Australian cohort
BackgroundChronic kidney disease progression to kidney failure is diverse, and progression may be different according to genetic aspects and settings...
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Diverse retinal-kidney phenotypes associated with NPHP1 homozygous whole-gene deletions in patients with kidney failure
A precise diagnosis in medicine allows appropriate disease-specific management. Kidney failure of unknown aetiology remains a frequent diagnostic...
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Incidental finding of acquired cystic kidney disease associated renal cell carcinoma in an adolescent with kidney failure
Acquired cystic kidney disease (ACKD) can occur in patients with chronic kidney disease and kidney failure, and its incidence increases with the...
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Prophylactic bilateral nephrectomy and preemptive kidney transplantation for Denys–Drash syndrome prior to development of kidney failure
BackgroundNephropathy in Denys–Drash syndrome (DDS) develops within a few months of birth, often progressing to kidney failure. Wilms tumors also...
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A kidney-brain neural circuit drives progressive kidney damage and heart failure
Chronic kidney disease (CKD) and heart failure (HF) are highly prevalent, aggravate each other, and account for substantial mortality. However, the...
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Intraoperative kidney replacement therapy in acute liver failure
Paediatric acute liver failure (PALF) is often characterised by its rapidity of onset and potential for significant morbidity and even mortality....
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External validation of the KFRE and Grams prediction models for kidney failure and death in a Spanish cohort of patients with advanced chronic kidney disease
BackgroundThe Kidney Failure Risk Equation (KFRE) is a 2- and 5-year kidney failure prediction model that is applied in chronic kidney disease (CKD)...
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Susceptibility to eye diseases in relation to age and kidney failure among Taiwanese adults
BackgroundThe kidney and eyes share common pathways and are thought to be closely connected. Chronic kidney disease and major eye diseases, such as...
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Dialysis after kidney transplant failure: how to deal with this daunting task?
The best treatment for patients with end-stage kidney disease is kidney transplantation, which, if successful provides both a reduction in mortality...
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Causes of kidney failure among patients undergoing maintenance hemodialysis in Somalia: a multi-center study
BackgroundKidney failure is one of the leading causes of morbidity and mortality worldwide. The incidence of kidney failure in Somalia has been...
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Initiation of the SGLT2 inhibitor canagliflozin to prevent kidney and heart failure outcomes guided by HbA1c, albuminuria, and predicted risk of kidney failure
BackgroundSodium glucose co-transporter-2 (SGLT2) inhibitors reduce the risk of kidney and heart failure events independent of glycemic effects. We...
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Acute renal failure after kidney transplantation due to mizoribine-induced ureteral stones
IntroductionMizoribine (MZR) is used to prevent rejection reactions after kidney transplantation and increase the risk of hyperuricemia. There is a...
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Kidney and urological involvement in Down syndrome: frequent, underestimated, but associated with impaired quality of life and risk of kidney failure
Patients with Down syndrome (DS) are at risk of multiorgan dysfunction; kidney and urological impairment are common. This is due to a likely...
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Heart failure subtype after acute kidney injury
IntroductionAcute kidney injury (AKI) is associated with increased risk of heart failure (HF). Determining the type of HF experienced by AKI...
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Kidney failure outcomes in children and young adults with sickle cell disease in the United States Renal Data System
BackgroundChildren and young adults with sickle cell disease (SCD) develop kidney disease early in childhood, with some patients progressing to...
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Acute kidney injury in acute liver failure: A narrative review
Acute kidney injury (AKI) is a frequent complication of acute liver failure (ALF) and it worsens the already worse prognoses of ALF. ALF is an...
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A targeted gene panel illuminates pathogenesis in young people with unexplained kidney failure
BackgroundKidney failure in young people is often unexplained and a significant proportion will have an underlying genetic diagnosis. National Health...
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Roles of PTH and FGF23 in kidney failure: a focus on nonclassical effects
Parathyroid hormone (PTH) and fibroblast growth factor 23 (FGF23) each play a central role in the pathogenesis of chronic kidney disease-mineral and...
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Managing Heart Failure in Chronic Kidney Disease: A Review of Current Literature
Purpose of ReviewThe purpose of this review was to discuss recent literature pertaining to the management of heart failure (HF) in patients with...
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Long-term social and professional outcomes in adults after pediatric kidney failure
BackgroundLittle is known about the long-term social and professional outcomes in adults after pediatric kidney replacement therapy (KRT). In this...
