Search
Search Results
-
SIUrO best practice recommendations to optimize BRCA 1/2 gene testing from DNA extracted from bone biopsy in mCRPC patients (BRCA Optimal Bone Biopsy Procedure: BOP)
The main guidelines and recommendations for the implementation of the BRCA1/2 somatic test do not focus on the clinical application of predictive...
-
Impact of Diagnosis and Treatment of Chronic Endometritis on Outcomes Before Starting Assisted Reproductive Technology: A Retrospective Study
This study aimed to investigate the effect of diagnosis and treatment of chronic endometritis (CE) on the outcome of assisted reproductive technology...
-
A novel embryo biopsy morphological analysis and genetic integrality criterion system significantly improves the outcome of preimplantation genetic testing
PurposeWhile efforts have been made to establish blastocyst grading systems in the past decades, little research has examined the quality of biopsy...
-
Application of Shear Wave Elastography and Contrast-Enhanced Ultrasound in Transrectal Prostate Biopsy
ObjectiveTo explore the clinical value of ultrasound shear wave elastography (SWE) and contrast-enhanced ultrasound (CEUS) in transrectal prostate...
-
Health Economic Evidence and Modeling Challenges for Liquid Biopsy Assays in Cancer Management: A Systematic Literature Review
BackgroundCancer-derived material circulating in the bloodstream and other bodily fluids, referred to as liquid biopsies (LBs), has become an...
-
The potential of cell-free and exosomal microRNAs as biomarkers in liquid biopsy in patients with prostate cancer
PurposeProstate cancer (PCa) is the 4th most diagnosed cancer and the 8th leading cause of cancer-related death worldwide. Currently, clinical risk...
-
Natural language processing deep learning models for the differential between high-grade gliomas and metastasis: what if the key is how we report them?
ObjectivesThe differential between high-grade glioma (HGG) and metastasis remains challenging in common radiological practice. We compare different...
-
“Add-Ons” for Assisted Reproductive Technology: Do Patients Get Honest Information from Fertility Clinics’ Websites?
“Add-on” procedures are actively promoted on some fertility clinic websites as proven means to improve IVF success rates, especially for couples with...
-
Lung nodule pre-diagnosis and insertion path planning for chest CT images
Medical image processing has proven to be effective and feasible for assisting oncologists in diagnosing lung, thyroid, and other cancers, especially...
-
Clinical practice guideline on the use of single-operator cholangioscopy in the diagnosis of indeterminate biliary stricture and the treatment of difficult biliary stones
Background and aimsSingle-operator cholangioscopy (SOC) offer a diagnostic and therapeutic alternative with an improved optical resolution over...
-
Toward confident prostate cancer detection using ultrasound: a multi-center study
PurposeDeep learning-based analysis of micro-ultrasound images to detect cancerous lesions is a promising tool for improving prostate cancer (PCa)...
-
An artificial intelligence model (euploid prediction algorithm) can predict embryo ploidy status based on time-lapse data
BackgroundFor the association between time-lapse technology (TLT) and embryo ploidy status, there has not yet been fully understood. TLT has the...
-
Identification of Hub Genes and Key Pathways Associated with Peripheral T-cell Lymphoma
Peripheral T-cell lymphoma (PTCL) is a very aggressive and heterogeneous hematological malignancy and has no effective targeted therapy. The...
-
Single-cell sequencing: a promising approach for uncovering the mechanisms of tumor metastasis
Single-cell sequencing (SCS) is an emerging high-throughput technology that can be used to study the genomics, transcriptomics, and epigenetics at a...
-
Multiple myeloma initially manifesting as a solitary deep ulcer on the tongue: a case study and literature review
BackgroundMultiple myeloma (MM) is a malignant disease associated with clonal plasma cell proliferative disorder, characterized by extensive...
-
A domain knowledge-based interpretable deep learning system for improving clinical breast ultrasound diagnosis
BackgroundThough deep learning has consistently demonstrated advantages in the automatic interpretation of breast ultrasound images, its black-box...
-
So You Want to Build Your Disease’s First Online Patient Registry: An Educational Guide for Patient Organizations Based on US and European Experience
Patient registries fulfill a number of key roles for clinicians, researchers, non-profit organizations, payers, and policy makers. They can help the...
-
Interleukin-7 Is Associated with Clinical and Pathological Activities in Immunoglobulin A Nephropathy and Protects the Renal Proximal Tubule Epithelium from Cellular Fibrosis
ObjectiveDiagnosis of immunoglobulin A nephropathy (IgAN) requires the evaluation of renal biopsy specimens. However, renal biopsy is an invasive...
-
SWOT analysis of noninvasive tests for diagnosing NAFLD with severe fibrosis: an expert review by the JANIT Forum
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease. Nonalcoholic steatohepatitis (NASH) is an advanced form of NAFLD...
-
Clinical diagnosis of prostate cancer using digital rectal examination and prostate-specific antigen tests: a systematic review and meta-analysis of sensitivity and specificity
BackgroundBeing diagnosed with cancer, irrespective of type initiates a serious psychological concern. The increasing rate of detection of indolent...