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1. Histological Correlates of Auditory Nerve Injury from Kainic Acid in the Budgerigar (Melopsittacus undulatus)

   Purpose

   Loss of auditory nerve afferent synapses with cochlear hair cells, called cochlear synaptopathy, is a common pathology in humans caused by...

   Yingxuan Wang, Kristina S. Abrams, ... Kenneth S. Henry in Journal of the Association for Research in Otolaryngology

   Article 05 October 2023
   

2. Synergistic neuroprotective action of prolactin and 17β-estradiol on kainic acid-induced hippocampal injury and long-term memory deficit in ovariectomized rats

   Purpose

   The neuroprotective actions of the ovarian hormone 17β-estradiol (E2) against different brain lesions have been constantly confirmed in a...

   Karen De la Torre, Marco Antonio Cerbón, ... Ofir Picazo in Hormones

   Article 16 April 2024
   

3. Prosaposin, a neurotrophic factor, protects neurons against kainic acid-induced neurotoxicity

   Prosaposin (PS) is the precursor of four sphingolipid activator proteins, saposin A–D. PS is both a precursor protein and a neuroprotective factor,...

   Hiroaki Nabeka in Anatomical Science International

   Article 03 February 2021
   

4. Excitatory amino acids, possible causative agents of nodding syndrome in eastern Africa

   Background

   Nodding syndrome (NS) is one type of epilepsy and a progressive disease characterized by nodding symptoms with children in sub-Saharan...

   Yasushi Miyauchi, Ayaka Shiraishi, ... Kiyoshi Kita in Tropical Medicine and Health

   Article Open access 19 May 2023
   

5. Effects of Kainic Acid-Induced Auditory Nerve Damage on Envelope-Following Responses in the Budgerigar (Melopsittacus undulatus)

   Sensorineural hearing loss is a prevalent problem that adversely impacts quality of life by compromising interpersonal communication. While hair cell...

   John L. Wilson, Kristina S. Abrams, Kenneth S. Henry in Journal of the Association for Research in Otolaryngology

   Article 19 October 2020
   

6. Examining the role of astrogliosis and JNK signaling in post-traumatic epilepsy

   Objective

   Post-traumatic epilepsy is a devastating complication of traumatic brain injury that has no targeted pharmacological therapy. Previous...

   Coulter Small, Abeer Dagra, ... Brandon Lucke-Wold in Egyptian Journal of Neurosurgery

   Article Open access 04 January 2022
   

7. Exploring with [¹⁸F]UCB-H the in vivo Variations in SV2A Expression through the Kainic Acid Rat Model of Temporal Lobe Epilepsy

   Purpose

   The main purpose of this study was to understand how the positron emission tomography (PET) measure of the synaptic vesicle 2A (SV2A) protein...

   Maria Elisa Serrano, Mohamed Ali Bahri, ... Alain Plenevaux in Molecular Imaging and Biology

   Article Open access 23 March 2020
   

8. Unlocking the potential of the 3-hydroxykynurenine/kynurenic acid ratio: a promising biomarker in adolescent major depressive disorder

   Metabolites disruptions in tryptophan (TRP) and kynurenine pathway (KP) are believed to disturb neurotransmitter homeostasis and contribute to...

   Zhihan Ye, Shuran Yang, ... Chuanyuan Kang in European Archives of Psychiatry and Clinical Neuroscience

   Article 31 May 2024
   

9. Neural Contributions to the Cochlear Summating Potential: Spiking and Dendritic Components

   Using electrocochleography, the summating potential (SP) is a deflection from baseline to tones and an early rise in the response to clicks. Here, we...

   Brendan T. Lutz, Kendall A. Hutson, ... Douglas C. Fitzpatrick in Journal of the Association for Research in Otolaryngology

   Article 07 March 2022
   

10. Transcranial photobiomodulation add-on therapy to valproic acid for pentylenetetrazole-induced seizures in peripubertal rats

    Background

    Convulsive status epilepticus (CSE) prevention is critical for pediatric patients with epilepsy. Immediate intervention before CSE reduce...

    Chung-Min Tsai, Shwu-Fen Chang, Hsi Chang in BMC Complementary Medicine and Therapies

    Article Open access 21 March 2022
    

11. Seizure-associated changes in the Golgi apparatus

    Heather Wood in Nature Reviews Neurology

    Article 09 October 2023

12. Reduced hippocampal inhibition and enhanced autism-epilepsy comorbidity in mice lacking neuropilin 2

    The neuropilin receptors and their secreted semaphorin ligands play key roles in brain circuit development by regulating numerous crucial neuronal...

    Carol Eisenberg, Deepak Subramanian, ... Tracy S. Tran in Translational Psychiatry

    Article Open access 18 October 2021
    

13. Neurobiology, Functions, and Relevance of Excitatory Amino Acid Transporters (EAATs) to Treatment of Refractory Epilepsy

    Epilepsy is one of the most prevalent and devastating neurological disorders characterized by episodes of unusual sensations, loss of awareness, and...

    Aleksey V. Zaitsev, Ilya V. Smolensky, ... Saak V. Ovsepian in CNS Drugs

    Article 14 September 2020
    

14. Neurosteroids alleviate seizures in rats

    Lisa Kiani in Nature Reviews Neurology

    Article 07 February 2024

15. The regulatory function of lncRNA and constructed network in epilepsy

    Background

    Epilepsy is a neurological disease characterized by neural network dysfunction. Although most reports indicate that the pathological...

    Suhui Kuang, Jiaqi Wang, ... Shuli Liang in Neurological Sciences

    Article 13 February 2023
    

16. Astrocyte dysregulation as an epileptogenic factor: a systematic review

    Background

    Epilepsy initiation involves multifactorial etiologies, including genetic susceptibility, structural anomalies, and glial cell...

    Komang Trisna Sumadewi, Bryan Gervais de Liyis, ... I Nyoman Mantik Astawa in The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

    Article Open access 10 June 2024
    

17. Effects of berberine on pentylenetetrazole-induced seizures during estrus cycle in rats

    Catamenial epilepsy is one of the central brain-related disorders associated with a menstrual cycle in some epileptic women. This study aimed to...

    Yasaman Asadollah-salmanpour, Shahin Hassanpour, Bita Vazir in Comparative Clinical Pathology

    Article 17 July 2023
    

18. [¹⁸F]DPA-714 PET imaging for the quantitative evaluation of early spatiotemporal changes of neuroinflammation in rat brain following status epilepticus

    Background

    Most antiepileptic drug therapies are symptomatic and adversely suppress normal brain function by nonspecific inhibition of neuronal...

    Ken-ichi Kaneko, Satsuki Irie, ... Yilong Cui in European Journal of Nuclear Medicine and Molecular Imaging

    Article 14 February 2022
    

19. Identification of potential crucial genes and therapeutic targets for epilepsy

    Background

    Epilepsy, a central neurological disorder, has a complex genetic architecture. There is some evidence suggesting that genetic factors play...

    Shitao Wang, Zhenrong **e, ... Zongyou Li in European Journal of Medical Research

    Article Open access 11 January 2024
    

20. Pharmacological Characterization of [¹⁸F]-FNM and Evaluation of NMDA Receptors Activation in a Rat Brain Injury Model

    Purpose

    NMDA receptors (NMDARs) dysfunction plays a central role in the physiopathology of psychiatric and neurodegenerative disorders whose...

    Marie Beaurain, Franck Talmont, ... Anne-Sophie Salabert in Molecular Imaging and Biology

    Article Open access 21 March 2023