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Showing 1-20 of 233 results
  1. Evaluation of hTERT, KRT7, and survivin in urine for noninvasive detection of bladder cancer using real‐time PCR

    Background

    Transitional cell carcinoma (TCC) of the bladder is the second most common genitourinary malignancy. Because of the low sensitivity of...

    Reza Yahyazadeh, Davood Bashash, ... Seyed H. Ghaffari in BMC Urology
    Article Open access 19 April 2021
  2. Comparison of Four Protocols for In Vitro Differentiation of Human Embryonic Stem Cells into Trophoblast Lineages by BMP4 and Dual Inhibition of Activin/Nodal and FGF2 Signaling

    Human embryonic stem cells (hESCs) cultured in media containing bone morphogenic protein 4 (BMP4; B) differentiate into trophoblast-like cells....

    Zahra Anvar, Imen Chakchouk, ... Ignatia B. Van den Veyver in Reproductive Sciences
    Article Open access 01 September 2023
  3. Identification of novel biomarkers, MUC5AC, MUC1, KRT7, GAPDH, CD44 for gastric cancer

    Gastric cancer (GC) is one of the most common malignant tumors in the world, and it is also the third largest cause of cancer-related death in the...

    Jie Yang in Medical Oncology
    Article Open access 27 March 2020
  4. Prognostic assessment capability of a five-gene signature in pancreatic cancer: a machine learning based-study

    Background

    A prognostic assessment method with good sensitivity and specificity plays an important role in the treatment of pancreatic cancer...

    Xuanfeng Zhang, Lulu Yang, ... Long Cui in BMC Gastroenterology
    Article Open access 11 March 2023
  5. A prognostic model based on immune-related long noncoding RNAs for patients with epithelial ovarian cancer

    Background

    Long noncoding RNAs (lncRNAs) are important regulators of gene expression and can affect a variety of physiological processes. Recent...

    Yao Peng, Hui Wang, ... Mingjun Zhang in Journal of Ovarian Research
    Article Open access 15 January 2022
  6. Rare histologic transformation of a CTNNB1 (β-catenin) mutated prostate cancer with aggressive clinical course

    Background

    Catenin (Cadherin-Associated Protein), Beta 1 ( CTNNB1) genomic alterations are rare in prostate cancer (PCa). Gain-of-function mutations...

    Dilara Akhoundova, Stefanie Fischer, ... Mark A. Rubin in Diagnostic Pathology
    Article Open access 21 June 2024
  7. Molecular and histopathological characterization of seminoma patients with highly elevated human chorionic gonadotropin levels in the serum

    Approximately 30% of seminoma (SEM) patients present with moderately elevated human chorionic gonadotropin (hCG) levels at first diagnosis. In case...

    Christoph Seidel, Finn-Ole Paulsen, ... Felix Bremmer in Virchows Archiv
    Article Open access 14 December 2023
  8. Heterotopia of salivary gland tissue in the pancreas

    Heterotopia of the salivary gland occurs mainly in the head and neck region of the human body, rarely in regions such as the rectum, but has never...

    Sandrina Martens, Katarina Coolens, ... Ilse Rooman in Diagnostic Pathology
    Article Open access 30 August 2023
  9. Bile level of cytokeratin 7 as a diagnostic marker for cholangiocarcinoma: a case-control study in Egyptian patients

    Background

    Cholangiocarcinoma (CCA) is an aggressive malignancy with a poor prognosis of less than 20% five-year survival rate. Early diagnosis is...

    Ali Nada, Alzhraa Alkhatib, ... Hossam El-Din Abdel-Latif in Egyptian Liver Journal
    Article Open access 15 June 2024
  10. Extraskeletal myxoid chondrosarcoma of the gingival: a rare case report and review of the literature

    Background

    Extraskeletal myxoid chondrosarcoma (EMC) is a rare malignant tumor described in the head and neck region, especially in the gingival. We...

    Jiaqi Li, Zhijian Zheng, ... Qi Han in Diagnostic Pathology
    Article Open access 13 September 2023
  11. Deep learning and transfer learning identify breast cancer survival subtypes from single-cell imaging data

    Background

    Single-cell multiplex imaging data have provided new insights into disease subtypes and prognoses recently. However, quantitative models...

    Shashank Yadav, Shu Zhou, ... Lana X. Garmire in Communications Medicine
    Article Open access 19 December 2023
  12. EWSR1-PATZ1 fusion renal cell carcinoma: a recurrent gene fusion characterizing thyroid-like follicular renal cell carcinoma

    Thyroid-like follicular renal cell carcinoma is an uncommon kidney tumor with no distinct molecular alteration described to date. This cohort of...

    Khaleel I. Al-Obaidy, Julia A. Bridge, ... David J. Grignon in Modern Pathology
    Article 07 June 2021
  13. Identification of adenoid subtype characterized with immune-escaped phenotype in lung squamous carcinoma based on transcriptomics

    Non-small cell lung cancer (NSCLC) is a heterogeneous disease, and its demarcation contributes to various therapeutic outcomes. However, a small...

    Jie Mei, Yun Cai, ... Yuan Wan in Experimental Hematology & Oncology
    Article Open access 12 October 2022
  14. Small molecule inhibitors targeting m6A regulators

    As the most common form of epigenetic regulation by RNA, N 6 methyladenosine (m 6 A) modification is closely involved in physiological processes, such...

    Guotai Feng, Yongya Wu, ... Guan Wang in Journal of Hematology & Oncology
    Article Open access 06 May 2024
  15. ALK-rearranged renal cell carcinoma with TPM3::ALK gene fusion and review of the literature

    ALK-rearranged renal cell carcinoma (ALK-RCC) is a very rare novel molecularly defined entity in the recently published fifth edition of the World...

    Laurence A. Galea, Michael S. Hildebrand, ... Ahmad Aga in Virchows Archiv
    Article 12 November 2022
  16. Mechanisms and pathophysiology of Barrett oesophagus

    Barrett oesophagus, in which a metaplastic columnar mucosa that can predispose individuals to cancer development lines a portion of the distal...

    Rhonda F. Souza, Stuart J. Spechler in Nature Reviews Gastroenterology & Hepatology
    Article 07 June 2022
  17. ZEB1 controls a lineage-specific transcriptional program essential for melanoma cell state transitions

    Cell plasticity sustains intra-tumor heterogeneity and treatment resistance in melanoma. Deciphering the transcriptional mechanisms governing...

    Simon Durand, Yaqi Tang, ... Julie Caramel in Oncogene
    Article Open access 22 March 2024
  18. Adenoid Cystic Carcinoma of Cervix: A Rare Entity

    Background

    Adenoid cystic carcinoma is a malignant neoplasm rarely occurring in the uterine cervix. It accounts for less than 1% of all cervical...

    Devika Chauhan, Aishwarya Sharma, ... Sankalp Sancheti in Indian Journal of Gynecologic Oncology
    Article 06 January 2024
  19. Fusobacterium Nucleatum Is a Risk Factor for Metastatic Colorectal Cancer

    Objective

    Increasing evidence has indicated that there is a correlation between Fusobacterium nucleatum ( F. nucleatum ) abundance and poor prognosis...

    Wen-dan Chen, **n Zhang, ... Yi Zhang in Current Medical Science
    Article 08 June 2022
  20. MOB kinase activator 1A acts as an oncogene by targeting PI3K/AKT/mTOR in ovarian cancer

    Background

    To illuminate the precise roles of MOB Kinase Activator 1 A (MOB1A) in the development of ovarian cancer (OC).

    Methods

    MOB1A expression and...

    Jian Lei, **g-Ying Xu, ... Juan Zhou in Discover Oncology
    Article Open access 14 June 2023
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