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The relationship between neurogenic dysphagia, stroke-associated pneumonia and functional outcome in a cohort of ischemic stroke patients treated with mechanical thrombectomy
IntroductionMechanical thrombectomy (MT) is an established treatment approach in acute ischemic stroke patients with large vessel occlusion (LVO)....
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Effects of acetazolamide combined with remote ischemic preconditioning on risk of acute mountain sickness: a randomized clinical trial
BackgroundWe aimed to determine whether and how the combination of acetazolamide and remote ischemic preconditioning (RIPC) reduced the incidence and...
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Lycium barbarum polysaccharide inhibits ischemia-induced autophagy by promoting the biogenesis of neural stem cells-derived extracellular vesicles to enhance the delivery of miR-133a-3p
BackgroundNeural stem cell-derived extracellular vesicles (NSC-EVs) mediated endogenous neurogenesis determines a crucial impact on spontaneous...
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Gasotransmitters and noble gases in cardioprotection: unraveling molecular pathways for future therapeutic strategies
Despite recent progress, ischemic heart disease poses a persistent global challenge, driving significant morbidity and mortality. The pursuit of...
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Use of mechanical preconditioning for free flaps in a swine model
BackgroundMechanical ischemic preconditioning (MIPC) is defined as applying brief periods of ischemia before tissue reperfusion. This mechanism...
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Differences in the components of metabolic syndrome by age and sex: a cross-sectional and longitudinal analysis of a cohort of middle-aged and older Japanese adults
BackgroundThe prevalence of metabolic syndrome (MetS) in Japan, a super-aged society, is increasing and poses a major public health issue. Several...
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The Role of Non-coding RNAs in Ischemic Myocardial Reperfusion Injury
MicroRNAs (miRNA) are non-coding RNAs that regulate gene expression in up to 90% of the human genome through interactions with messenger RNA (mRNA)....
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Photobiomodulation, alone or combined with adipose-derived stem cells, reduces inflammation by modulation of microRNA-146a and interleukin-1ß in a delayed-healing infected wound in diabetic rats
Diabetic wounds are categorized by chronic inflammation, leading to the development of diabetic foot ulcers, which cause amputation and death....
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Comparison of smokers’ mortality with non-smokers following out-of-hospital cardiac arrests: a systematic review and meta-analysis
ObjectiveAlthough some studies have linked smoking to mortality after out-of-hospital cardiac arrests (OHCAs), data regarding smoking and mortality...
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Egr-1 functions as a master switch regulator of remote ischemic preconditioning-induced cardioprotection
Despite improved treatment options myocardial infarction (MI) is still a leading cause of mortality and morbidity worldwide. Remote ischemic...
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Endovascular stroke treatment using balloon guide catheters may reduce penumbral tissue damage and improve long-term outcome
ObjectivesDuring mechanical recanalization of large vessel occlusions (LVO), the use of proximal flow arrest with balloon guide catheters (BGC) was...
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Effect of Obstructive Sleep Apnea on Outcomes After Traumatic Brain Injury: A Retrospective Cohort Analysis
BackgroundTraumatic brain injury (TBI) and obstructive sleep apnea (OSA) are common in the general population and are associated with significant...
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Efficacy of remote ischaemic preconditioning on outcomes following non-cardiac non-vascular surgery: a systematic review and meta-analysis
BackgroundRemote ischaemic preconditioning (RIPC) has been investigated as a simple intervention to potentially mitigate the ischaemic effect of the...
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The correlation of hemoglobin and 28-day mortality in septic patients: secondary data mining using the MIMIC-IV database
BackgroundPrevious studies found minimal evidence and raised controversy about the link between hemoglobin and 28-day mortality in sepsis patients....
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Clinical and anamnestic features of patients with systemic vasculitis: a single-center retrospective study
Systemic vasculitides are the most complex and problematic autoimmune rheumatic diseases characterized by affections of large, medium, or small...
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Recommendations on palliative care aspects in intensive care medicine
BackgroundThe timely integration of palliative care is important for patients suffering from various advanced diseases with limited prognosis. While...
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High intramuscular adipose tissue content as a precondition of sarcopenia in patients with aortic aneurysm
PurposeSarcopenia is a major problem of the elderly. Although little is known about the cause of sarcopenia, the intramuscular adipose tissue content...
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Portal venous contrast enhancement ratio of the adrenal glands and spleen as prognostic marker of mortality in patients with acute mesenteric ischemia
PurposeContrast enhancement of the adrenal gland defined by computed tomography (CT) was previously analyzed as a prognostic factor for critically...
