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Non-coding RNAs as therapeutic targets and biomarkers in ischaemic heart disease
The adult heart is a complex, multicellular organ that is subjected to a series of regulatory stimuli and circuits and has poor reparative potential....
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Impact of implementing Dutch versus European guideline risk factor targets in older patients with ischaemic heart disease
BackgroundIn patients with ischaemic heart disease (IHD) aged > 70 years, Dutch and European guidelines recommend different treatment targets:...
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Ischemic Heart Disease From Diagnosis to Treatment
This book describes the different aspects of ischemic heart disease, one of the leading causes of death in industrialized countries, and whose...
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Influence of prior myocardial infarction on outcome in patients with ischaemic HFrEF: insights from the EVIdence based TreAtment in Heart Failure (EVITA-HF) registry
BackgroundThere is scarce information about the influence of prior myocardial infarction (pMI) on outcomes in patients (pts) with ischaemic HFrEF. We...
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Incidence of atrial fibrillation, ischaemic heart disease and heart failure in patients with diabetes
BackgroundDiabetes has strongly been linked to atrial fibrillation, ischaemic heart disease and heart failure. The epidemiology of these...
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Monocyte to high-density lipoprotein cholesterol ratio predicts poor outcomes in ischaemic heart failure patients combined with diabetes: a retrospective study
BackgroundThe prevalence of ischaemic heart failure (HF) continues to increase. Diabetes mellitus (DM) concomitant with ischaemic HF increases the...
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Burden of ischaemic heart disease and attributable risk factors among Nan**g adults in China from 2011 to 2017
BackgroundIschemic heart disease (IHD) is a major barrier to sustainable human development and is associated with various modifiable risk factors....
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Percutaneous left stellate ganglion block for refractory ventricular tachycardia in structural heart disease: our single-centre experience
IntroductionWhen electrical storm (ES) is amenable to neither antiarrhythmic drugs, nor deep sedation or catheter ablation, autonomic modulation may...
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Role of obesity and hypertension in the incidence of atrial fibrillation, ischaemic heart disease and heart failure in patients with diabetes
In a cohort study performed using primary care databases in a General Practitioners Network, Groenewegen et al. report a clear association between...
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Relationships between intracranial arterial dolichoectasia and small vessel disease in patients with ischaemic stroke: a systematic review and meta-analysis
BackgroundIntracranial arterial dolichoectasia (IADE) is a common arterial finding of dilation, elongation, or both, affecting large intracranial...
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The Nottingham Ischaemic Cardiovascular Magnetic Resonance resource (NotIs CMR): a prospective paired clinical and imaging scar database—protocol
IntroductionResearch utilising artificial intelligence (AI) and cardiovascular magnetic resonance (CMR) is rapidly evolving with various objectives,...
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Antiplatelet Agents and Oral Anticoagulant Use in Patients with Atrial Fibrillation and Carotid Artery Disease After First-Time Ischaemic Stroke
IntroductionPeople with atrial fibrillation (AF) frequently have competing mechanisms for ischaemic stroke, including extracranial carotid...
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Estimation and determinants of direct medical costs of ischaemic heart disease, stroke and hypertensive heart disease: evidence from two major hospitals in Cameroon
BackgroundCardiovascular disease (CVD) is the largest contributor to the non-communicable diseases (NCD) burden in Cameroon, but data on its economic...
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Prevention and treatment of ischaemic and haemorrhagic stroke in people with diabetes mellitus: a focus on glucose control and comorbidities
Diabetes mellitus is a significant risk factor for both ischaemic and haemorrhagic stroke, affecting up to a third of individuals with...
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Absolute iodine concentration for dynamic perfusion imaging of the myocardium: improved detection of poststenotic ischaemic in a 3D-printed dynamic heart phantom
BackgroundTo investigate the detection capabilities of myocardial perfusion defects of dual-energy computed tomography (CT) technology using...
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Valvular heart disease and cardiomyopathy: reappraisal of their interplay
Cardiomyopathies and valvular heart diseases are typically considered distinct diagnostic categories with dedicated guidelines for their management....
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Three-year incidence and acute setting predictors of epilepsy after neonatal and childhood arterial ischaemic stroke: a disease-based cohort study
To assess the association between clinical and MRI characteristics of arterial ischaemic stroke (AIS) and the 3-year risk of post-stroke epilepsy...
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Sleep duration and risk of stroke and coronary heart disease: a 9-year community-based prospective study of 0.5 million Chinese adults
BackgroundThere is uncertainty about the optimum sleep duration for risk of different subtypes of stroke and ischaemic heart disease.
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Serum angiopoietin-1 concentration does not distinguish patients with ischaemic stroke from those presenting to hospital with ischaemic stroke mimics
BackgroundA previous study found that circulating angiopoietin-1 (angpt-1) concentrations were significantly lower in patients who had a recent...