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Intratumoral and peritumoral radiomics predict pathological response after neoadjuvant chemotherapy against advanced gastric cancer
BackgroundTo investigate whether intratumoral and peritumoral radiomics may predict pathological responses after neoadjuvant chemotherapy against...
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Prediction of neoadjuvant chemotherapy pathological complete response for breast cancer based on radiomics nomogram of intratumoral and derived tissue
BackgroundNon-invasive identification of breast cancer (BCa) patients with pathological complete response (pCR) after neoadjuvant chemotherapy (NACT)...
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Development and validation of peritumoral vascular and intratumoral radiomics to predict pathologic complete responses to neoadjuvant chemotherapy in patients with triple-negative breast cancer
BackgroundTo develop and validate a peritumoral vascular and intratumoral radiomics model to improve pretreatment predictions for pathologic complete...
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Intratumoral metastasis of sigmoid colon cancer to chromophobe renal cell carcinoma: a case report
We herein report an extremely rare case of intratumoral metastasis of colon cancer to chromophobe renal cell carcinoma. A 71-year-old woman was...
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Awareness of intratumoral bacteria and their potential application in cancer treatment
Hitherto, the recognition of the microbiota role in tumorigenesis and clinical studies mostly focused on the intestinal flora. In contrast to the gut...
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Intratumoral T cell depletion following neoadjuvant chemotherapy in patients with muscle-invasive bladder cancer is associated with poor clinical outcome
BackgroundWhereas neoadjuvant cisplatin-based chemotherapy (NAC) followed by a radical cystectomy remains the standard treatment for patients with...
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Intratumoral and peritumoral CT-based radiomics for predicting the microsatellite instability in gastric cancer
PurposeTo investigate the value of intratumoral and peritumoral radiomics based on contrast-enhanced computer tomography (CECT) to preoperatively...
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Intratumoral and peritumoral radiomics for preoperative prediction of neoadjuvant chemotherapy effect in breast cancer based on contrast-enhanced spectral mammography
ObjectiveTo investigative the performance of intratumoral and peritumoral radiomics based on contrast-enhanced spectral mammography (CESM) to...
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Association between high expression of intratumoral fibroblast activation protein and survival in patients with intrahepatic cholangiocarcinoma
BackgroundCancer-associated fibroblasts (CAFs) have been reported to exhibit protumorigenic effects. Among the well-known CAF markers such as smooth...
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Impact of intratumoral microbiome on tumor immunity and prognosis in human pancreatic ductal adenocarcinoma
BackgroundRecent evidence suggests that the presence of microbiome within human pancreatic ductal adenocarcinoma (PDAC) tissue potentially influences...
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Intratumoral and peritumoral CT radiomics in predicting prognosis in patients with chondrosarcoma: a multicenter study
ObjectiveTo evaluate the efficacy of the CT-based intratumoral, peritumoral, and combined radiomics signatures in predicting progression-free...
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Intratumoral microbiota: roles in cancer initiation, development and therapeutic efficacy
Microorganisms, including bacteria, viruses, fungi, and other eukaryotes, play critical roles in human health. An altered microbiome can be...
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Synergistic combination therapy using cowpea mosaic virus intratumoral immunotherapy and Lag-3 checkpoint blockade
Immune checkpoint therapy (ICT) for cancer can yield dramatic clinical responses; however, these may only be observed in a minority of patients....
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Multiparametric MRI-based intratumoral and peritumoral radiomics for predicting the pathological differentiation of hepatocellular carcinoma
PurposeTo explore the predictive potential of intratumoral and multiregion peritumoral radiomics features extracted from multiparametric MRI for...
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The molecular signature and prognosis of glioma with preoperative intratumoral hemorrhage: a retrospective cohort analysis
BackgroundIntratumoral hemorrhage, though less common, could be the first clinical manifestation of glioma and is detectable via MRI; however, its...
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Intratumoral calcification: not only a diagnostic but also a prognostic indicator in oligodendrogliomas
ObjectiveCalcification is a hallmark characteristic of oligodendroglioma (ODG) that may be used as a diagnostic factor, but its prognostic...
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Prognostic significance of T lymphocyte subgroups (CD4 and CD8) in lung cancer patients after neoadjuvant chemotherapy
ObjectiveThe basis for current and future lung cancer immunotherapy depends on our knowledge of molecular mechanisms of interactions between tumor...
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Clinically relevant molecular hallmarks of PFA ependymomas display intratumoral heterogeneity and correlate with tumor morphology
Posterior fossa type A (PF-EPN-A, PFA) ependymoma are aggressive tumors that mainly affect children and have a poor prognosis. Histopathology shows...
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Computed Tomography-derived intratumoral and peritumoral radiomics in predicting EGFR mutation in lung adenocarcinoma
ObjectiveTo investigate the value of Computed Tomography (CT) radiomics derived from different peritumoral volumes of interest (VOIs) in predicting...
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Intratumoral catheter placement in pediatric patients with diffuse midline gliomas
IntroductionDiffuse midline brainstem gliomas have a poor prognosis and are generally not amenable to surgical resection. Occasionally, palliative...
