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Artesunate prevents knee intraarticular adhesion via PRKR-like ER kinase (PERK) signal pathway
BackgroundIntraarticular scar adhesion refers to a serious complication caused by knee surgery or trauma, leading to various sequelae (e.g.,...
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Homoharringtonine inhibits fibroblasts proliferation, extracellular matrix production and reduces surgery-induced knee arthrofibrosis via PI3K/AKT/mTOR pathway-mediated apoptosis
BackgroundThe prevention of surgery-induced intraarticular fibrosis remains a challenge following orthopedic surgery. Homoharringtonine (HHT) has...
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Comparison between acupotomy and corticosteroid injection for patients diagnosed with different classifications of tennis elbow: a randomized control trial
BackgroundTennis elbow has long been one of the most controversial subjects in orthopaedics. Many scholars thought the use of open or arthroscopic...
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Cubital tunnel syndrome: anatomy, pathology, and imaging
Cubital tunnel syndrome (CuTS) is the second most common peripheral neuropathy in the upper limb. It occurs due to ulnar nerve compression within the...
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Types and doses of anti-adhesive agents injected into subacromial space do not have an effect on the clinical and anatomical outcomes after arthroscopic rotator cuff repair
PurposeJoint stiffness after arthroscopic rotator cuff repair is a major concern for orthopaedic surgeons. Various antiadhesive agents are commonly...
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Promising results of captopril in improving knee arthrofibrosis and cartilage status: an animal model study
PurposeSeveral cytokines and growth factors start and progress the destruction process of joint hyaline cartilage and fibrosis formation. Captopril...
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An update on rehabilitative treatment of shoulder disease after breast cancer care
According to the latest statistics of the American Cancer Society 2022, breast cancer is a leading cause of morbidity and death among women...
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The role of leukotriene inhibition using a 5-lipoxygenase (5-LO) inhibitor in a joint contracture model
PurposeArthrofibrosis is a common inflammatory complication of joint trauma and surgery. 5lipoxygenase (5-LO) is a key enzyme involved in...
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Open reduction and internal fixation of Ideberg type IA glenoid fractures: Tricks, pearls, and potential pitfalls based on a retrospective cohort of 33 patients focusing on the rehabilitation protocol
IntroductionThe standard treatment of anterior glenaoid fractures carrying > 20% of the glenoid fossa is open reduction and internal fixation (ORIF)....
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Clinical Guidelines in the Management of Frozen Shoulder: An Update!
Among all the prevalent painful conditions of the shoulder, frozen shoulder remains one of the most debated and ill-understood conditions. It is a...
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Decellularized extracellular matrix mediates tissue construction and regeneration
Contributing to organ formation and tissue regeneration, extracellular matrix (ECM) constituents provide tissue with three-dimensional (3D)...
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The effect of the platelet-rich plasma and ozone therapy on tendon-to-bone healing in the rabbit rotator cuff repair model
BackgroundThe aim of this study is to histologically and biomechanically investigate the effects of local PRP and ozone therapy (O 2 O 3 ) on...
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Intra-articular Adenosine, Lidocaine and Magnesium (ALM) solution decreases postoperative joint fibrosis in an experimental knee implant model
BackgroundThere is currently no drug therapy to prevent arthrofibrosis following knee surgery. We aimed to determine if the anti-ischemic and...
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Stem cell-based therapy for human diseases
Recent advancements in stem cell technology open a new door for patients suffering from diseases and disorders that have yet to be treated. Stem...
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Arthroscopic and Endoscopic Management of Posttraumatic Hindfoot Stiffness
Ankle, hindfoot, and toe stiffness can result from hindfoot trauma. It can be due to capsular fibrosis, tendon adhesion, muscle fibrosis, or...
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Reduction of intraarticular adhesion of knee by local application of rapamycin in rabbits via inhibition of fibroblast proliferation and collagen synthesis
BackgroundThe formation of intraarticular adhesion is a common complication after total knee arthroplasty or anterior cruciate ligament...
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All-arthroscopic release for treating severe knee extension contractures could improve the knee range of motion and the mid-term functional outcomes
PurposeTo evaluate the safety, feasibility, and effectiveness of an all-arthroscopic technique for the intra- and extraarticular release of severe...
