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Intra-patient variability of iodine quantification across different dual-energy CT platforms: assessment of normalization techniques
ObjectivesTo investigate intra-patient variability of iodine concentration (IC) between three different dual-energy CT (DECT) platforms and to...
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Impact of intra-patient variability of tacrolimus on allograft function and CD4 + /CD8 + ratio in kidney transplant recipients: a retrospective single-center study
BackgroundTacrolimus is a critical component of immunosuppressive therapy for kidney transplant recipients. Intra-patient variation (IPV) of...
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Delineating the intra-patient heterogeneity of molecular alterations in treatment-naïve colorectal cancer with peritoneal carcinomatosis
In a non-negligible number of patients with metastatic colorectal cancer (mCRC), the peritoneum is the predominant site of dissemination. Cure can be...
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Integrated single-cell transcriptome analysis of CD34 + enriched leukemic stem cells revealed intra- and inter-patient transcriptional heterogeneity in pediatric acute myeloid leukemia
To gain insights into the idiosyncrasies of CD34 + enriched leukemic stem cells, we investigated the nature and extent of transcriptional...
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Explainable machine learning via intra-tumoral radiomics feature map** for patient stratification in adjuvant chemotherapy for locoregionally advanced nasopharyngeal carcinoma
PurposeThis study aimed to discover intra-tumor heterogeneity signature and validate its predictive value for adjuvant chemotherapy (ACT) following...
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Using digital phenoty** to capture depression symptom variability: detecting naturalistic variability in depression symptoms across one year using passively collected wearable movement and sleep data
Major Depressive Disorder (MDD) presents considerable challenges to diagnosis and management due to symptom variability across time. Only recent work...
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Intra- and inter-individual cognitive variability in schizophrenia and bipolar spectrum disorder: an investigation across multiple cognitive domains
There is substantial cognitive heterogeneity among patients with schizophrenia (SZ) and bipolar disorders (BD). More knowledge about the magnitude...
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Dasatinib anhydrate containing oral formulation improves variability and bioavailability in humans
Dasatinib monohydrate indicated for the treatment of chronic myeloid leukemia displays pH-dependent solubility. The aim of reported development...
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Effects of Intra-operative Cardiopulmonary Variability On Post-operative Pulmonary Complications in Major Non-cardiac Surgery: A Retrospective Cohort Study
Intraoperative cardiopulmonary variables are well-known predictors of postoperative pulmonary complications (PPC), traditionally quantified by median...
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Neural variability in three major psychiatric disorders
Across the major psychiatric disorders (MPDs), a shared disruption in brain physiology is suspected. Here we investigate the neural variability at...
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Relationship between visit-to-visit blood pressure variability and depressive mood in Korean primary care patients
BackgroundHigh blood pressure variability (BPV) increases the risk of cardiovascular disease and may be better prognostic factor than blood pressure....
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Variability of transient elastography-based spleen stiffness performed at 100 Hz
BackgroundSpleen stiffness measurement (SSM) performed by transient elastography at 100 Hz is a novel technology for the evaluation of portal...
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Intra-articular therapies: patient preferences and professional practices in European countries
To assess patient perspective and professional practice of intraarticular therapies (IATs) across Europe, an expert international multidisciplinary...
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Inter- and intra-observer variability of qualitative visual breast-composition assessment in mammography among Japanese physicians: a first multi-institutional observer performance study in Japan
BackgroundVisual assessment of mammographic breast composition remains the most common worldwide, although subjective variability limits its...
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Evaluating inter-individual variability captured by the Eleveld pharmacokinetics model
Inter-individual variability in Pharmacokinetic (PK) and Pharmacodynamic (PD) models significantly affects the accuracy of Target Controlled Infusion...
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The influence of lifestyle and biological factors on semen variability
PurposeSemen parameters are subjected to within-individual variability over time. The driving factors for this variability are likely...
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Glucose variability: a new risk factor for cardiovascular disease
Aims and data synthesisGlucose variability (GV) is increasingly considered an additional index of glycemic control. Growing evidence indicates that...
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Intra-scan inter-tissue variability can help harmonize radiomics features in CT
ObjectiveWe studied the repeatability and the relative intra-scan variability across acquisition protocols in CT using phantom and unenhanced...
