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Internal mammary lymph node metastasis in breast cancer patients based on anatomical imaging and functional imaging
Internal mammary lymph node (IMLN) metastasis forms part of the clinical node classification for primary breast cancer, which influences the...
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Impact of breath hold on regional nodal irradiation and heart volume in field in left breast cancer adjuvant irradiation
PurposeCompared to the free-breathing technique, adjuvant left breast irradiation after breast-conserving surgery or mastectomy using the breath-hold...
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Oncological Safety of Skip** Axillary Lymph Node Dissection in Patients with Clinical N0, Sentinel Node-Positive Breast Cancer Undergoing Total Mastectomy
ObjectiveThis study aimed to determine whether sentinel lymph node biopsy (SLNB) alone could afford oncological outcomes comparable with axillary...
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Regional Nodal Irradiation and Post-Mastectomy Radiation Therapy After Up-Front Surgery
Purpose of ReviewThis review serves to summarize available data impacting treatment decisions for the use of post-mastectomy radiation (PMRT) and...
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Utilization patterns and temporal trends of internal mammary nodal irradiation at a tertiary cancer center
PurposeThe role and uptake of internal mammary nodal irradiation (IMNI) is variable. This study was designed to quantify the rates and determinants...
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Impact of axillary surgery on outcome of clinically node positive breast cancer treated with neoadjuvant chemotherapy
PurposeAxillary Lymph Node Dissection (ALND) is recommended for breast cancer patients who present with clinically node positive disease (cN1)...
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Internal mammary node irradiation improves 8-year survival in breast cancer patients: results from a retrospective cohort study in real-world setting
BackgroundRegional nodal irradiation (RNI) improves disease outcome in breast cancer patients, but the contribution of internal mammary node...
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Incidental axillary dose delivery to axillary lymph node levels I–III by different techniques of whole-breast irradiation: a systematic literature review
Background and objectiveIn breast cancer treatment, radiotherapy is an essential component for locoregional management. Axillary recurrence in...
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Implementation of the Targeted Axillary Dissection Procedure in Clinically Node-Positive Breast Cancer: A Retrospective Analysis
BackgroundThe targeted axillary dissection (TAD) procedure is used in clinically positive lymph node (cN+) breast cancer to assess whether...
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Lymph node metastasis in cancer progression: molecular mechanisms, clinical significance and therapeutic interventions
Lymph nodes (LNs) are important hubs for metastatic cell arrest and growth, immune modulation, and secondary dissemination to distant sites through a...
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Added value of repeat sentinel lymph node biopsy in FDG-PET/CT node-negative patients with ipsilateral breast cancer recurrence
PurposeRepeat sentinel lymph node biopsy (rSLNB) has been suggested for axillary staging in clinically node-negative (cN0) patients with ipsilateral...
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Partial-accelerated irradiation with stereotactic radiotherapy at a dose of 30 Gy in 5 fractions in early breast cancer
PurposeTo evaluate feasibility of accelerated partial breast irradiation (APBI) using stereotactic radiotherapy (SBRT) Thirty Gy delivered in 5...
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Determinants of radiation dose to immune cells during breast radiotherapy
BackgroundThe immune system has been identified as an organ at risk in esophageal and lung cancers. However, the dosimetric impact of radiotherapy on...
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A case of contralateral inguinal lymph node metastases from breast cancer
BackgroundBreast cancer is well known to tends to invade through the lymphatic chains mainly to the axillary and subclavian nodes or occasionally to...
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Annual report of the Japanese Breast Cancer Registry for 2019
This is an annual report by the Japanese Breast Cancer Society regarding the clinical data on breast cancer extracted from the National Clinical...
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Quantitative assessment of breast volume changes after whole-breast irradiation for breast cancer using breast auto-segmentation
PurposeThis study aimed to quantitatively estimate the changes in breast volume associated with radiotherapy in patients undergoing breast-conserving...
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De-escalation of Post-mastectomy Irradiation in Hormone Receptor-Positive Breast Cancer with One to Three Positive Nodes
BackgroundThe 21-gene recurrence score (RS) is used to predict benefit from chemotherapy in hormone receptor (HR)-positive breast cancer with one to...
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Pattern of practice of re-irradiation for ipsilateral breast tumor recurrence in Italy: a survey by the Italian Association of Radiotherapy and Clinical Oncology (AIRO)
PurposeThe Re-irradiation and the Breast Cancer Working Groups of the Italian Association of Radiotherapy and Clinical Oncology (AIRO) conducted a...
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Cardiac dose in the treatment of synchronous bilateral breast cancer patients between three different radiotherapy techniques (VMAT, IMRT, and 3D CRT)
PurposeSynchronous bilateral irradiation of both mammary glands and chest wall is a challenging task due to technical difficulties and limited...
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Changes in Radiation Therapy: New Ultrahypofractionated Radiation, Repeat Breast Conservation Therapy in the Management of Breast Recurrence with Re-irradiation, Proton Therapy
Purpose of ReviewManagement of breast cancer is multidisciplinary, balancing local and systemic control between treatment modalities. Surgical,...