Search
Search Results
-
Interleukin-37 is involved in the immunopathogenesis of infectious mononucleosis
BackgroundMultiple immunopathological responses to viruses are observed in infectious mononucleosis (IM), a manifestation of primary infection with...
-
Role of nuclear factor kappa B, interleukin-19, interleukin-34, and interleukin-37 expression in diabetic nephropathy
BackgroundThe long-term effects of diabetes mellitus (DM) can impair several organs, including the kidney, resulting in serious health problems....
-
Interleukin-37 promotes colitis-associated carcinogenesis via SIGIRR-mediated cytotoxic T cells dysfunction
Interleukin-37b (hereafter called IL-37) was identified as fundamental inhibitor of natural and acquired immunity. The molecular mechanism and...
-
Interleukin-37: associations of plasma levels and genetic variants in gout
ObjectivesIL-37 is an anti-inflammatory cytokine involved in inflammatory and autoimmune diseases. We aimed to investigate the association between...
-
Interleukin-37 as an anti-inflammatory cytokine: does its relation to disease activity suggest its potential role in rheumatoid arthritis therapy?
BackgroundThis study aimed to measure the serum and synovial interleukin (IL)-37 levels in rheumatoid arthritis (RA) patients compared to patients...
-
Serum interleukin-37 level and interleukin-37 gene polymorphism in patients with Behçet disease
Behçet’s disease (BD) is a chronic inflammatory disease. The etiopathogenesis of BD is not well understood and several cytokines and genetic factors...
-
Peripheral blood microR-146a and microR-29c expression in children with Mycoplasma pneumoniae pneumonia and its clinical value
BackgroundWe investigated changes in microR-29c and microR-146a expression in the serum of children with Mycoplasma pneumoniae pneumonia, analysed...
-
Allicin protects against LPS-induced cardiomyocyte injury by activating Nrf2-HO-1 and inhibiting NLRP3 pathways
BackgroundAllicin is a bioactive compound with potent antioxidative activity and plays a protective effect in myocardial damage and fibrosis. The...
-
Evaluation of the safety and immunological effects of Bacillus Calmette–Guérin in combination with checkpoint inhibitor therapy in a patient with neuroendocrine carcinoma: a case report
BackgroundImmune checkpoint inhibitors have revolutionized therapy of advanced and metastatic cancers. However, a significant proportion of patients...
-
Urticaria after breakthrough Omicron BA.5.1 severe acute respiratory syndrome coronavirus 2 infection in a triple-vaccinated (Pfizer) patient: a case report
BackgroundSevere acute respiratory syndrome coronavirus 2 continues to threaten public health. The virus is causing breakthrough infections in...
-
Morphological and molecular characterization of Linguatula serrata and evaluation of the health status of the infested dogs
Linguatula serrata is a neglected parasitic zoonosis with less research recorded throughout the globe on the physiological and immunological...
-
Could cooling dialysate improve inflammatory and nutritional status of hemodialysis patients?
BackgroundIt has been shown that dialysate cooling (lowering the dialysate temperature to 0.5 °C below central body temperature) reduces the...
-
Looking into the Kinetics of NT-proBNP and sST2 Changes in Patients with Heart Failure Treated with Sacubitril/Valsartan: A Hint to Different Therapeutic Pathways
Background and objectiveN-terminal pro-B-type natriuretic peptide (NT-proBNP) and soluble interleukin 1 receptor-like 1 ST2 (sST2) are biomarkers...
-
Effect of surgical pleth index-guided remifentanil administration on perioperative outcomes in elderly patients: a prospective randomized controlled trial
BackgroundDuring general anesthesia, the surgical pleth index (SPI) monitors nociception. The evidence of SPI in the elderly remains scarce. We aimed...
-
A Canadian Retrospective Chart Review Evaluating Concomitant Methotrexate De-escalation Patterns in Patients with Rheumatoid Arthritis Treated with Biologic or Targeted Synthetic DMARDs
IntroductionRheumatoid arthritis (RA) guidelines recommend methotrexate (MTX)-anchored therapy with biologic or targeted synthetic disease-modifying...
-
Increased serum interleukin-37 (IL-37) levels correlate with oxidative stress parameters in Hashimoto’s thyroiditis
PurposeInterleukin-37 (IL-37), member of the IL-1 family, is a natural suppressor of immune and inflammatory responses. Increased serum IL-37 levels...
-
Interleukin-6 and granulocyte colony-stimulating factor as predictors of the prognosis of influenza-associated pneumonia
BackgroundPneumonia is a common complication of influenza and closely related to mortality in influenza patients. The present study examines...
-
Real-World Persistence and Treatment Patterns in Patients with Psoriatic Arthritis Treated with Anti-IL17 Therapy in Spain: The PerfIL-17 Study
IntroductionGiven the growing interest and use of interleukin-17 inhibitors (anti-IL17) for the treatment of psoriatic arthritis (PsA), an...
-
Ultrasonography of heel entheses in axial spondyloarthritis patients: frequency and assessment of associated factors
PurposeFoot entheses involvement is a common manifestation of spondyloarthritis. The superiority of ultrasonography examination in foot entheses...