Search
Search Results
-
Assessment of interleukin-18 gene polymorphism and serum levels in cutaneous lichen planus
BackgroundLichen planus (LP) is a chronic inflammatory disease with uncertain etiology. Interleukin-18 (IL-18) is an interferon gamma (INFγ) inducing...
-
Monoclonal Antibodies Against Mature Interleukin-18 Ameliorate Colitis and Repair Goblet Cell Function
BackgroundNumerous biological interventions and small molecules are used to treat Crohn’s disease; however, the effectiveness of these treatments...
-
Elevated free interleukin-18 associated with severity and mortality in prospective cohort study of 206 hospitalised COVID-19 patients
BackgroundDivergence between deterioration to life-threatening COVID-19 or clinical improvement occurs for most within the first 14 days of symptoms....
-
Acute stress induces severe neural inflammation and overactivation of glucocorticoid signaling in interleukin-18-deficient mice
Interleukin-18 (IL18) is an inflammatory cytokine that is related to psychiatric disorders such as depression and cognitive impairment. We previously...
-
Peripheral Interleukin-18 is negatively correlated with abnormal brain activity in patients with depression: a resting-state fMRI study
BackgroundInterleukin-18 (IL-18) may participate in the development of major depressive disorder, but the specific mechanism remains unclear. This...
-
Interleukin 18 and IL-18 BP response to Sars-CoV-2 virus infection
The immune response to the SARS-CoV-2 infection is crucial to the patient outcome. IL-18 is involved in the lymphocyte response to the disease and it...
-
Interleukin 18, soluble cluster of differentiation 40, platelet factor 4 variant 1, and neutrophil gelatinase-associated lipocalin can be used as biomarkers to aid activity and diagnosis in ocular Behçet’s disease
PurposeThe molecules human interleukin (IL-18), the soluble cluster of differentiation (sCD40), platelet factor 4 variant 1 (PF4V1), and neutrophil...
-
Micromorphological features and interleukin 6, 8, and 18 expressions in post-mortem lung tissue in cases with acute respiratory distress syndrome
The purpose of this study was to analyze the presence of interleukins 6, 8, and 18 in post-mortem lung tissue of subjects deceased due to polytrauma....
-
Caspase-1 and interleukin-18 in children with post infectious bronchiolitis obliterans: a case–control study
The exact immunological mechanisms of post infectious bronchiolitis obliterans (PIBO) in childhood are not fully known. It has been shown that the...
-
Increased expression of NLRP3 inflammasome components in granulosa cells and follicular fluid interleukin(IL)-1beta and IL-18 levels in fresh IVF/ICSI cycles in women with endometriosis
The inflammasomes are a family of recently described multi-protein cytoplasmic sensors that orchestrate the inflammatory response and participate in...
-
Interleukin-18 polymorphism as a diagnostic tumor marker for hepatocellular carcinoma in patients with hepatitis C-related cirrhosis
BackgroundEgypt has the highest hepatitis C virus prevalence worldwide where about 24% of the people are estimated to carry HCV and more than 50% of...
-
Interleukin-18 and fibroblast growth factor 2 in combination is a useful diagnostic biomarker to distinguish adult-onset Still’s disease from sepsis
ObjectiveTo identify potential biomarkers to distinguish adult-onset Still’s disease (AOSD) from sepsis.
MethodWe recruited 70 patients diagnosed...
-
Unicentric Castleman’s disease in the parotid gland associated with psoriasis: a case report
BackgroundCastleman’s disease is a rare lymphoproliferative disorder that is often misdiagnosed because of its untypical clinical or imaging features...
-
[18F]FDG PET-MR characterization of aortitis in the IL1rn−/− mouse model of giant-cell arteritis
BackgroundMetabolic imaging is routinely used to demonstrate aortitis in patients with giant-cell arteritis. We aimed to investigate the preclinical...
-
The Link Between Seminal Cytokine Interleukin 18, Female Circulating Regulatory T Cells, and IVF/ICSI Success
Seminal plasma (SP) is thought to be a crucial factor which affects the expansion of regulatory T cells (Tregs) in female reproductive tract during...
-
Dietary lysozyme and avilamycin modulate gut health, immunity, and growth rate in broilers
BackgroundAttempts to use dietary lysozyme (LYZ) as an alternative to antibiotics in broilers have been successful, but further research is needed...
-
Clinical-grade N-(4-[18F]fluorobenzoyl)-interleukin-2 for PET imaging of activated T-cells in humans
BackgroundMolecular imaging of immune cells might be a potential tool for response prediction, treatment evaluation and patient selection in...
-
Factors related to central nervous system involvement of primary vitreoretinal lymphoma
PurposeThis single center retrospective study aimed to investigate the factors associated with central nervous system (CNS) involvement of primary...
-
Pro- and anti-inflammatory cytokines are the game-changers in childhood obesity-associated metabolic disorders (diabetes and non-alcoholic fatty liver diseases)
Childhood obesity is a chronic inflammatory epidemic that affects children worldwide. Obesity affects approximately 1 in 5 children worldwide....
-
Natural compound library screening to identify berberine as a treatment for rheumatoid arthritis
ObjectiveFibroblast-like synoviocytes (FLS) play a critical role on the exacerbation and deterioration of rheumatoid arthritis (RA). Aberrant...
