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Methamphetamine (MA) use and MA-induced psychosis are associated with increasing aberrations in the compensatory immunoregulatory system, interleukin-1α, and CCL5 levels
There are only a few studies reporting on the immunological profiles of methamphetamine (MA) use, MA dependency, or MA-induced psychosis (MAP). This...
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Safety of YAG laser vitreolysis for intraocular tissues: analysis of postoperative complications
PurposeTo evaluate the safety of yttrium–aluminum-garnet (YAG) laser vitreolysis for intraocular tissues.
MethodsThirty-six New Zealand rabbits were...
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Effect of continuous positive airway pressure treatment on Th17/Treg imbalance in patients with obstructive sleep apnea and a preliminary study on its mechanism
BackgroundObstructive sleep apnea (OSA) can be considered a chronic inflammatory disease that impacts all bodily systems, including the immune...
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IL-6 regulates epithelial ovarian cancer EMT, invasion, and metastasis by modulating Let-7c and miR-200c through the STAT3/HIF-1α pathway
Interleukin-6 (IL-6) and hypoxia-inducible factor-1α (HIF-1α) play important roles in epithelial-mesenchymal transformation (EMT) and tumor...
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Exercise following joint distraction inhibits muscle wasting and delays the progression of post-traumatic osteoarthritis in rabbits by activating PGC-1α in skeletal muscle
ObjectiveMuscle wasting frequently occurs following joint trauma. Previous research has demonstrated that joint distraction in combination with...
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Increased IL-1α expression in chronic rhinosinusitis with nasal polyps
PurposeTo examine whether and how interleukin (IL)-1α is involved in chronic rhinosinusitis with nasal polyps (CRSwNP).
MethodsNasal polyp (NP) and...
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A high-trans fat, high-carbohydrate, high-cholesterol, high-cholate diet-induced nonalcoholic steatohepatitis mouse model and its hepatic immune response
Non-alcoholic fatty liver disease (NAFLD) is a chronic progressive disease that can progress to non-alcoholic steatohepatitis (NASH). Animal models...
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The prognostic role of HIF-1α and NF-κB expression in RAS wild-type metastatic colorectal cancer: A Turkish Oncology Group (TOG) study
BackgroundNot all RAS wild-type metastatic colorectal cancer (mCRC) patients experience the same benefit from anti-epidermal growth factor receptor...
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RETRACTED ARTICLE: The profile of the key pro-inflammatory cytokines in the serum of patients with CD and their association with the disease severity and activity
BackgroundThe epidemiology of Crohn’s disease (CD) has changed over the past decades, demonstrating a trend toward increased prevalence in develo**...
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Low-Nutrient Environment-Induced Changes in Inflammation, Cell Proliferation, and PGC-1α Expression in Stromal Cells with Ovarian Endometriosis
Although nutrient status plays an important role in cell metabolism, its significance in endometriosis is obscure. Herein, we investigated the...
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LuQi Formula relieves ventricular remodeling through improvement of HIF-1α-mediated intestinal barrier integrity
BackgroundVentricular remodeling is the adaptive process in which the heart undergoes changes due to stress, leading to heart failure (HF). The...
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Adult zebrafish infected by clinically isolated Klebsiella pneumoniae with different virulence showed increased intestinal inflammation and disturbed intestinal microbial biodiversity
BackgroundKlebsiella pneumoniae is a pathogen that often infects patients in clinical practice. Due to its high virulent and drug resistance,...
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Perinatal inflammation, fetal growth restriction, and long-term neurodevelopmental impairment in Bangladesh
BackgroundThere are limited data on the impact of perinatal inflammation on child neurodevelopment in low-middle income countries and among...
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Granulocyte macrophage colony-stimulating factor-induced macrophages of individuals with autism spectrum disorder adversely affect neuronal dendrites through the secretion of pro-inflammatory cytokines
BackgroundA growing body of evidence suggests that immune dysfunction and inflammation in the peripheral tissues as well as the central nervous...
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Longitudinal Assessment of Blood-Based Inflammatory, Neuromuscular, and Neurovascular Biomarker Profiles in Intensive Care Unit–Acquired Weakness: A Prospective Single-Center Cohort Study
BackgroundThe diagnosis of intensive care unit (ICU)-acquired weakness (ICUAW) and critical illness neuromyopathy (CINM) is frequently hampered in...
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Anti-inflammatory potential of simvastatin and amfenac in ARPE-19 cells; insights in preventing re-detachment and proliferative vitreoretinopathy after rhegmatogenous retinal detachment surgery
PurposeRhegmatogenous retinal detachment is a severe vision-threatening complication that can result into proliferative vitreoretinopathy (PVR) and...
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Comparison of Interleukin-1 Ligand Expression by Human Papilloma Virus Status in HNSCCs
Interleukin-1 alpha (IL-1α) is a cytokine involved in the acute phase immune response and its expression is upregulated in a variety of solid tumors...
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Changes in concentrations of cervicovaginal immune mediators across the menstrual cycle: a systematic review and meta-analysis of individual patient data
BackgroundHormonal changes during the menstrual cycle play a key role in sha** immunity in the cervicovaginal tract. Cervicovaginal fluid contains...
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Time course of serum cytokine level changes within 72 h after onset in children with acute encephalopathy and febrile seizures
BackgroundCytokine levels have been measured in acute encephalopathy (AE) to determine its pathology or as a diagnostic biomarker to distinguish it...
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Pyoderma Gangrenosum: An Updated Literature Review on Established and Emerging Pharmacological Treatments
Pyoderma gangrenosum is a rare inflammatory skin disease classified within the group of neutrophilic dermatoses and clinically characterized by...
