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Rational use of inhaled corticosteroids for the treatment of COPD
Inhaled corticosteroids (ICS) are the mainstay of treatment for asthma, but their role in chronic obstructive pulmonary disease (COPD) is debated....
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Effect of fracture risk in inhaled corticosteroids in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis
BackgroundThe fracture risk of patients with chronic obstructive pulmonary disease (COPD) treated with inhaled corticosteroids is controversial. And...
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Prescribing practices of inhaled corticosteroids for premature infants in the neonatal intensive care unit
ObjectiveDespite limited safety and efficacy data, inhaled corticosteroids (ICS) are prescribed to premature infants in the neonatal intensive care...
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Inhaled corticosteroids do not affect the antibody titer against the SARS-CoV-2 spike protein in BNT162b2 mRNA vaccinated patients
ObjectivesOral corticosteroids reduce the antibody titer of the BNT162b2 mRNA vaccine against SARS-CoV-2. To date, the effect of inhaled...
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Use of thiols and implications for the use of inhaled corticosteroids in the presence of oxidative stress in COPD
BackgroundOxidative stress and persistent airway inflammation are thought to be important contributors to the development of chronic obstructive...
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Cough Response to High-Dose Inhaled Corticosteroids in Patients with Chronic Cough and Fractional Exhaled Nitric Oxide Levels ≥ 25 ppb: A Prospective Study
This study aimed to investigate the effects of high-dose inhaled corticosteroids (ICS) on chronic cough patients with elevated fractional exhaled...
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Effect of Long-term Inhaled Corticosteroids on the Hypothalamic-Pituitary-Adrenal Axis in Children with Asthma
ObjectivesTo assess the effect of the long-term use of inhaled corticosteroids (ICS) on the hypothalamic-pituitary-adrenal (HPA) axis.
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Inhaled Corticosteroids in Adults with Non-cystic Fibrosis Bronchiectasis: From Bench to Bedside. A Narrative Review
Due to their potent anti-inflammatory capacity (particularly in predominantly eosinophilic inflammation) and immunosuppressive properties, inhaled...
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Biomarker-guided withdrawal of inhaled corticosteroids in asthma patients with a non-T2 inflammatory phenotype – a randomized controlled trial study protocol
BackgroundNon-T2 asthma is characterized by the absence of elevated type 2 inflammatory biomarkers such as blood-eosinophils, total and...
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Association of GAB1 gene with asthma susceptibility and the efficacy of inhaled corticosteroids in children
Asthma is a polygenic disease that may onset during childhood. Inhaled corticosteroids (ICS) are the main therapy in asthma, although their efficacy...
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Quantitative comparison of different inhaled corticosteroids in the treatment of asthma in children
BackgroundThe GINA recommends inhaled corticosteroids (ICSs) for the treatment of steps 2–3 of childhood asthma. However, the difference in efficacy...
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Inhaled corticosteroids, COPD, and the incidence of lung cancer: a systematic review and dose response meta-analysis
BackgroundThere has been debate on whether inhaled corticosteroids (ICS) reduce the incidence of lung cancer amongst patients with Chronic...
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Several Nocardia abcessus bronchiolitis in a patient treated with inhaled corticosteroids: a case report
Nocardiosis is a disease that mainly affects immunocompromised patients. Inhaled corticosteroids (ICS) are standard of care for asthma. This...
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Pharmacological Basis of Differences in Dose Response, Dose Equivalence, and Duration of Action of Inhaled Corticosteroids
IntroductionAsthma treatment guidelines classify inhaled corticosteroid (ICS) regimens as low, medium, or high dose. However, efficacy and safety are...
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Probability of successful inhaled corticosteroids cessation in preschool wheezers: a predictive score
Nearly all asthma predictive tools estimate the future risk of asthma development. However, there is no tool to predict the probability of successful...
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A descriptive cohort study of withdrawal from inhaled corticosteroids in COPD patients
Inhaled corticosteroid (ICS) therapy is widely prescribed without a history of exacerbations and consensus guidelines suggest withdrawal of ICS in...
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Intraclass comparison of inhaled corticosteroids for the risk of pneumonia in chronic obstructive pulmonary airway disorder: a network meta-analysis and meta-regression
BackgroundInhalational corticosteroids (ICS) were observed to increase the pneumonia risk in chronic obstructive pulmonary airway disorder (COPD)....
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Up-regulation of ACE2, the SARS-CoV-2 receptor, in asthmatics on maintenance inhaled corticosteroids
BackgroundThe first step in SARS-CoV-2 infection is binding of the virus to angiotensin converting enzyme 2 (ACE2) on the airway epithelium. Asthma...
