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A case of pancreatic PEComa with prominent inflammatory cell infiltration: the inflammatory subtype is a distinct histologic group of PEComa
BackgroundPEComa is a mesenchymal tumor that can occur in various organs including the uterus and soft tissues. PEComas are composed of perivascular...
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Higher inflammatory response in hepatocellular carcinoma is associated with immune cell infiltration and a better outcome
Background and aimsHepatocellular carcinoma (HCC) often develops from chronic liver inflammation. Inflammation within a tumor can either promote...
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Correlation among post-surgery recurrence of CRSwNP and TCM syndromes and tissue inflammatory cell infiltration type: a study protocol
BackgroundFunctional endoscopic sinus surgery is a principal option for treating chronic rhinosinusitis with nasal polyps (CRSwNP) after medication...
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An inflammatory response-related gene signature can predict the prognosis and impact the immune infiltration of multiple myeloma
Multiple myeloma (MM) is a highly heterogeneous and incurable disease. Inflammation plays a vital role in cancer genesis and progression. However,...
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An alternative posterior ascending pulmonary artery treatment in lobectomy with inflammatory lymph node infiltration
BackgroundLobectomy may be a challenging treatment option in lung cancer with inflammatory lymph node infiltration. Moreover, the en-masse lobectomy...
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Aqueous extract of Platycodon grandiflorus attenuates lipopolysaccharide-induced apoptosis and inflammatory cell infiltration in mouse lungs by inhibiting PI3K/Akt signaling
BackgroundAcute lung injury (ALI), an acute inflammatory lung disease, can cause a rapid inflammatory response in clinic, which endangers the...
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Optic nerve sheath infiltration in dysthyroid optic neuropathy
PurposeTo assess the association of optic nerve sheath (ONS) infiltration, fat infiltration, and scleral enhancement with active thyroid eye disease...
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Identifying prognostic biomarker related to immune infiltration in acute myeloid leukemia
The immune cells of tumor microenvironment (TME) constitute a vital element of the tumor tissue. There is increasing evidence for their clinical...
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Spatially variant immune infiltration scoring in human cancer tissues
The Immunoscore is a method to quantify the immune cell infiltration within cancers to predict the disease prognosis. Previous immune profiling...
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Predicting diagnostic biomarkers associated with immune infiltration in Crohn's disease based on machine learning and bioinformatics
ObjectiveThe objective of this study is to investigate potential biomarkers of Crohn's disease (CD) and the pathological importance of infiltration...
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Neutrophils in Inflammatory Bone Diseases
Purpose of ReviewIn this review, we summarize the current evidence that suggests that neutrophils play a key role in facilitating damage to local...
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Macrophage subpopulations in pediatric patients with lupus nephritis and other inflammatory diseases affecting the kidney
BackgroundMacrophages play an important role in the pathogenesis of lupus nephritis (LN), but less is known about macrophage subtypes in pediatric...
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Correlation of CT-based radiomics analysis with pathological cellular infiltration in fibrosing interstitial lung diseases
PurposeWe aimed to identify computed tomography (CT) radiomics features that are associated with cellular infiltration and construct CT radiomics...
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Fatty infiltration in the posterior muscles of the lower extremities as an MRI feature in antimitochondrial antibody–associated myopathy
ObjectiveIdiopathic inflammatory myopathy (IIM) with antimitochondrial M2 antibody (AMA-M2) has been associated with distinct clinical...
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Identifying Immune Cell Infiltration and Hub Genes Related to M2 Macrophages in Endometriosis by Bioinformatics Analysis
Endometriosis (EM) is a chronic, estrogen-dependent inflammatory disease. Presently, the pathophysiology of EM is still unclear, and numerous studies...
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Identification of immune cell infiltration and effective biomarkers of polycystic ovary syndrome by bioinformatics analysis
BackgroundPatients with polycystic ovary syndrome (PCOS) exhibit a chronic inflammatory state, which is often accompanied by immune, endocrine, and...
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Proteoglycan-4 is an essential regulator of synovial macrophage polarization and inflammatory macrophage joint infiltration
Abstract BackgroundSynovial macrophages perform a multitude of functions that include clearance of cell debris and foreign bodies, tissue immune...
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Testicular leukaemic infiltration in relapsed acute lymphoblastic leukaemia: a case report
BackgroundAlthough paediatric patients with acute lymphoblastic leukaemia (ALL) have improved survival following modern chemotherapy treatment,...
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Pulmonary inflammatory leiomyosarcoma represents a potential diagnostic pitfall of DNA methylation-based classification of sarcomas: a case report
BackgroundPulmonary inflammatory leiomyosarcoma (PILMS) is a rare type of myogenic tumor with prominent lymphohistiocytic infiltration. Despite their...
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Metformin increases the expression of proinflammatory cytokines and inhibits supraspinatus fatty infiltration
BackgroundAfter a rotator cuff (RC) tendon tear, the supraspinatus (SS) inflammatory response induces fatty infiltration (FI). Metformin has the...