Search
Search Results
-
The design, implementation, and impact of an automated patient-reported outcome data collection and adverse event surveillance tool: a randomized trial
BackgroundIncorporating patient-reported outcome measures into routine clinical care can improve the patient experience, increase engagement, and...
-
A Proposal of a Cost-Effectiveness Modeling Approach for Heart Failure Treatment Assessment: Considering the Short- and Long-Term Impact of Hospitalization on Event Rates
BackgroundThe rate of events such as recurrent heart failure (HF) hospitalization and death are known to dramatically increase directly after HF...
-
Impact of Event Scale-6 (IES-6) for U.S. adults who experienced the COVID-19 pandemic
BackgroundCOVID-19 pandemic causes psychological problems such as stress. It is important to accurately identify the level of stress and establish...
-
Adverse Event Profiles of Antiseizure Medications and the Impact of Coadministration on Drug Tolerability in Adults with Epilepsy
BackgroundAntiseizure medication (ASM) as monotherapy or in combination is the treatment of choice for most patients with epilepsy. Therefore,...
-
Impact of Sub-patent Malaria During Pregnancy on Birth-Weight in Odisha, India: Time-to-Event Analysis of Prospective Longitudinal Follow-Up of a Survey
ObjectiveThe current study aimed to estimate prevalence of malaria infection, especially sub-patent infection, in pregnant women residing in high...
-
The effects of COVID-19 event strength on job burnout among primary medical staff
BackgroundAs a global pandemic, The Corona Virus Disease 2019 (COVID-19) has brought significant challenges to the primary health care (PHC) system....
-
Impact of pre-event testing and quarantine on reducing the risk of COVID-19 epidemic rebound: a modelling study
BackgroundWith the evolving growth of the COVID-19 epidemic, travel restriction policies would need to be adjusted accordingly. Prohibition of mass...
-
Budget Impact Analysis of Risperidone Use and Adverse Event Monitoring in Autism Spectrum Disorder in Brazil: Assessment of Theoretical Versus Real Data
Background and aimsRisperidone is used in autism spectrum disorder (ASD) to manage aggressive behavior. Budget impact analysis (BIA) assists managers...
-
Interprofessional clinical event debriefing-does it make a difference? Attitudes of emergency department care providers to INFO clinical event debriefings
BackgroundDebriefing is increasingly used in clinical environments. Surveys indicate staff support for debriefing clinical events, but little is...
-
Identifying strategies to support implementation of interprofessional primary care teams in Nova Scotia: Results of a survey and knowledge sharing event
BackgroundInterprofessional primary care teams (IPCTs) work together to enhance care. Despite evidence on the benefits of IPCTs, implementation...
-
Interpretation Bias and Adolescent Social Anxiety: The Mediating Effect of Pre- and Post-Event Rumination
BackgroundInterpretation bias (IB), pre- and post-event rumination are related to adolescent social anxiety (SA). However, although postulated...
-
The impact of bleeding event frequency on health-related quality of life and work productivity outcomes in a European cohort of adults with haemophilia A: insights from the CHESS II study
BackgroundHaemophilia A carries a substantial healthcare burden, affecting health-related quality of life (HRQoL). The Cost of Haemophilia in Men: a...
-
Another market segment: sport event tourism by disabled athletes
Sports and tourism are connected in various parts of economies, cultures, and nations. However, there has been a limited understanding of sports...
-
Impact of limited sample size and follow-up on single event survival extrapolation for health technology assessment: a simulation study
IntroductionExtrapolation of time-to-event data from clinical trials is commonly used in decision models for health technology assessment (HTA). The...
-
Strengthening event-based surveillance (EBS): a case study from Afghanistan
The sustained instability in Afghanistan, along with ongoing disease outbreaks and the impact of the COVID-19 pandemic, has significantly affected...
-
Data mining and analysis of adverse event signals associated with teprotumumab using the Food and Drug Administration adverse event reporting system database
BackgroundTeprotumumab was approved by the US Food and Drug Administration (FDA) for the treatment of thyroid eye disease in 2020. However, its...
-
Development and Application of a Data-Driven Signal Detection Method for Surveillance of Adverse Event Variability Across Manufacturing Lots of Biologics
IntroductionPostmarketing drug safety surveillance research has focused on the product-patient interaction as the primary source of variability in...
-
Sociodemographic Characteristics of Adverse Event Reporting in the USA: An Ecologic Study
IntroductionThe Food and Drug Administration Adverse Event Reporting System (FAERS) is a vital source of new drug safety information, but whether...
-
An exploratory assessment of the impact of a novel risk assessment test on breast cancer clinic waiting times and workflow: a discrete event simulation model
BackgroundBreast cancer clinics across the UK have long been struggling to cope with high demand. Novel risk prediction tools – such as the PinPoint...
-
Adverse events in single-arm clinical trials with non-fatal time-to-event efficacy endpoint: from clinical questions to methods for statistical analysis
BackgroundIn any single-arm trial on novel treatments, assessment of toxicity plays an important role as occurrence of adverse events (AEs) is...
