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Immunotherapy for recurrent or metastatic nasopharyngeal carcinoma
Immunotherapy, particularly immune checkpoint inhibitors (ICIs), such as anti-programmed death 1/programmed death-ligand 1 (PD-1/PD-L1) therapy, has...
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Informing immunotherapy with multi-omics driven machine learning
Progress in sequencing technologies and clinical experiments has revolutionized immunotherapy on solid and hematologic malignancies. However, the...
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Alleviating hypoxia to improve cancer immunotherapy
Tumor hypoxia resulting from abnormal and dysfunctional tumor vascular network poses a substantial obstacle to immunotherapy. In fact, hypoxia...
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Nanoparticles in tumor microenvironment remodeling and cancer immunotherapy
Cancer immunotherapy and vaccine development have significantly improved the fight against cancers. Despite these advancements, challenges remain,...
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Clinical immunotherapy in pancreatic cancer
Pancreatic cancer remains a challenging disease with limited treatment options, resulting in high mortality rates. The predominant approach to...
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Intratumoural immunotherapy plus focal thermal ablation for localized prostate cancer
Major advances have been made in the use of immunotherapy for the treatment of solid tumours, including the use of intratumourally injected...
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Recent highlights of cancer immunotherapy
Cancer immunotherapy represents a groundbreaking paradigm shift in the field of cancer treatment, harnessing the power of the immune system to combat...
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Advances in nano-immunotherapy for hematological malignancies
Hematological malignancies (HMs) encompass a diverse group of blood neoplasms with significant morbidity and mortality. Immunotherapy has emerged as...
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Current approaches in glioblastoma multiforme immunotherapy
Glioblastoma multiform (GBM) is the most prevalent CNS (central nervous system) tumor in adults, with an average survival length shorter than 2 years...
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Immune landscape and response to oncolytic virus-based immunotherapy
Oncolytic virus (OV)-based immunotherapy has emerged as a promising strategy for cancer treatment, offering a unique potential to selectively target...
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Emerging evidence for adapting radiotherapy to immunotherapy
Immunotherapy has revolutionized the clinical management of many malignancies but is infrequently associated with durable objective responses when...
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Artificial intelligence in immunotherapy PET/SPECT imaging
ObjectiveImmunotherapy has dramatically altered the therapeutic landscape for oncology, but more research is needed to identify patients who are...
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The Roots and Growth of Allergen Immunotherapy
Purpose of ReviewThe purpose of this review is to present the history of allergen immunotherapy.
Recent FindingsAn overview of allergen...
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Refining mutanome-based individualised immunotherapy of melanoma using artificial intelligence
Using the particular nature of melanoma mutanomes to develop medicines that activate the immune system against specific mutations is a game changer...
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Current status and prospect of immunotherapy for colorectal cancer
PurposeColorectal cancer is the most common gastrointestinal tumor in China. While significant progress has been achieved in traditional...
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Perioperative Immunotherapy in Non-Small Cell Lung Cancer
The standard of care in patients with early-stage non-small cell lung cancer (NSCLC) following surgical resection has been adjuvant chemotherapy for...
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Current status of vaccine immunotherapy for gastrointestinal cancers
Recent advances in tumor immunology and molecular drug development have ushered in a new era of cancer immunotherapy. Immunotherapy has shown...
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Tumor metabolic crosstalk and immunotherapy
Tumor cells must resist the host's immune system while maintaining growth under harsh conditions of acidity and hypoxia, which indicates that tumors...
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Immunotherapy in Esophagogastric Cancer: Treatment Landscape, Challenges, and New Directions
BackgroundCancers of the upper gastrointestinal tract represent a lethal disease entity comprising the esophagus, gastroesophageal junction, and...
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Geriatric Assessment in the Era of Targeted and Immunotherapy
Cancer is a disease that mostly affects older adults and because of the aging of the population, the number of older adults diagnosed with cancer...