Search
Search Results
-
Extracellular vesicle-mediated immunoregulation in cancer
Extracellular vesicles (EVs) have emerged as immunomodulatory regulators during tumor progression. These small vesicles encapsulate a variety of...
-
Macrophages in immunoregulation and therapeutics
Macrophages exist in various tissues, several body cavities, and around mucosal surfaces and are a vital part of the innate immune system for host...
-
-
CD155 immunoregulation as a target for natural killer cell immunotherapy in glioblastoma
Natural killer (NK) cells are powerful immune effectors, modulating their anti-tumor function through a balance activating and inhibitor ligands on...
-
The effects of aqueous extract of Maca on energy metabolism and immunoregulation
BackgroundIn the present work, we investigated the effects of aqueous extract of Maca (AEM) on energy metabolism and immunoregulation in...
-
Integrative analysis of the immune-related ceRNA network in fetal growth restriction based on weighted gene co-expression network analysis
PurposeImmune disorders lead to placental dysfunction and fetal growth restriction (FGR), but current research on the immune regulation mechanisms of...
-
Discovery and repurposing of artemisinin
Malaria is an ancient infectious disease that threatens millions of lives globally even today. The discovery of artemisinin, inspired by traditional...
-
Hypoprolactinemia. Does it matter? Redefining the hypopituitarism and return from a mumpsimus
Prolactin (PRL) is secreted by the lactotroph cells in the anterior pituitary gland which is under inhibitory control of dopamine. The mature human...
-
A novel ceRNA-immunoregulatory axis based on immune cell infiltration in ulcerative colitis-associated colorectal carcinoma by integrated weighted gene co-expression network analysis
BackgroundPatients with ulcerative colitis are at an increased risk of develo** colorectal cancer with a prolonged disease course. Many studies...
-
Increased Expression of TGF-β1 Contributes to the Downregulation of Progesterone Receptor Expression in the Eutopic Endometrium of Infertile Women with Minimal/Mild Endometriosis
Endometriosis is a hormone-dependent disease associated with impaired immunoregulation. In our recent study, we have characterized the trascriptomic...
-
TIM-3 as a promising target for cancer immunotherapy in a wide range of tumors
T-cell immunoglobulin and mucin domain-containing protein 3 (TIM-3) expression has been a trending topic in recent years due to its differential...
-
The therapeutic potential of immunoengineering for systemic autoimmunity
Disease-modifying drugs have transformed the treatment options for many systemic autoimmune diseases. However, an evolving understanding of disease...
-
Disulfiram enhances chemotherapeutic effects of doxorubicin liposomes against human hepatocellular carcinoma via activating ROS-induced cell stress response pathways
PurposeIncreasing evidences have revealed the anti-cancer effect of disulfiram. Current disulfiram-based cancer therapies still have limitations,...
-
Expression of nuclear factor kappa B in ovine maternal inguinal lymph nodes during early pregnancy
BackgroundPregnancy-induced immunological changes contribute to the maternal immune tolerance. Nuclear factor kappa B (NF-κB) pathway participates in...
-
Traditional application and modern pharmacological research of Eucommia ulmoides Oliv.
As a Traditional Chinese Medicine, Eucommia ulmoides Oliv. has been used for the treatment of various diseases since ancient times, involving lumbar...
-
The role of diosgenin in crohn’s disease
Inflammatory bowel disease (IBD) is a chronic idiopathic inflammation that can grossly affect the entire gastrointestinal tract (GIT) from the mouth...
-
Excessive Immune Activation and the Correlation with Decreased Expression of PD-1 at the Maternal–Fetal Interface in Preeclampsia
The etiology of preeclampsia (PE) is still unknown, and excessive immune activation is an important component of its pathogenesis. Programmed cell...
-
Allergic Rhinitis and House Dust Mite Sensitization Determine Persistence of Asthma in Children
ObjectiveTo specify clinical and immunological parameters of the mechanisms, which may lead to development of persistent asthma, or regression of the...
-
Echinacoside exhibits antidepressant-like effects through AMPAR–Akt/ERK–mTOR pathway stimulation and BDNF expression in mice
BackgroundSeveral natural products have been demonstrated to be effective in the treatment of depressive disorders. Echinacoside, a naturally...
-
Neuroinflammation in schizophrenia: the role of nuclear factor kappa B
Neuroinflammation, particularly in the dorsolateral prefrontal cortex, is well-established in a subset of people with schizophrenia, with significant...
