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Safflower Yellow Inhibits Progression of Hepatocellular Carcinoma by Modulating Immunological Tolerance via FAK Pathway
ObjectiveTo explore the anti-tumor effect of safflower yellow (SY) against hepatocellular carcinoma (HCC) and the underlying potential mechanism.
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Role of Immunological Testing in Infertility
Purpose of ReviewUnexplained infertility, recurrent pregnancy loss, and recurrent implantation failure are challenging clinical scenarios, both for...
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Immunological memory in rheumatic inflammation — a roadblock to tolerance induction
Why do we still have no cure for chronic inflammatory diseases? One reason could be that current therapies are based on the assumption that chronic...
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Textbook of Allergen Tolerance
Allergies are a significant health issue, yet few books exist on allergen tolerance of separation; here the author classifies allergen tolerance...
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Anti-sperm Antibodies as an Increasing Threat to Male Fertility: Immunological Insights, Diagnostic and Therapeutic Strategies
It is a fact that sperm possess antigenic properties. Substantial scientific research suggests that specific antibodies that attach to sperm antigens...
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Prognosis and immunological characteristics of HDAC family in pan-cancer through integrative multi-omic analysis
BackgroundThe histone deacetylase (HDAC) family plays a significant role in a variety of biological processes related to cancer, such as metabolism...
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Immunological and metabolic characteristics of the Omicron variants infection
The Omicron variants of SARS-CoV-2, primarily authenticated in November 2021 in South Africa, has initiated the 5th wave of global pandemics. Here,...
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Investigating the immunological function of alpha-2-glycoprotein 1, zinc-binding in regulating tumor response in the breast cancer microenvironment
BackgroundAlpha-2-glycoprotein 1, zinc-binding (ZAG), a secreted protein encoded by the AZGP1 gene, is structurally similar to HLA class I. Despite...
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Immunological signatures and predictive biomarkers for first-generation somatostatin receptor ligand resistance in Acromegaly
PurposePredicting resistance to first-generation Somatostatin Receptor Ligands (fg-SRL) in Acromegaly patients remains an ongong challenge....
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Correlation between neuropsychiatric systemic lupus erythematosus and immunological markers: a real-world retrospective study
ObjectivesThis study aimed to investigate disparities in clinical profiles and autoantibody patterns between patients with and without...
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Immunological Mechanisms in Allergic Contact Dermatitis
Purpose of the reviewThe understanding of the cellular and molecular pathogenesis of allergic contact dermatitis (ACD) has increased dramatically.
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Advances in Immune Tolerance Induction in Enzyme Replacement Therapy
Inborn errors of metabolism (IEMs) are a group of genetic diseases that occur due to the either deficiency of an enzyme involved in a...
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Two patients with ZAP-70 deficiency in China present with a different genetic, immunological, and clinical phenotype
Zeta(ζ)-Chain Associated Protein Kinase 70 kDa (ZAP-70) deficiency is a rare autosomal recessive primary immunodeficiency disease. Little is known...
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Gut microbiota and acute kidney injury: immunological crosstalk link
The gut microbiota, often called the "forgotten organ," plays a crucial role in bidirectional communication with the host for optimal physiological...
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Immunological Underpinnings of Autoimmune Primary Ovarian Insufficiency
Purpose of ReviewPrimary ovarian insufficiency (POI) is a heterogenous disease with numerous causes, affecting ~ 1% of women in the USA. The...
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Unique 40-year survival after heart transplantation with normal graft function and spontaneous operational tolerance
Unique 40-year survival after heart transplantation with normal graft function and spontaneous operational tolerance.
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Immunological insights into hypertension: unraveling triggers and potential therapeutic avenues
Hypertension remains the leading cause of morbidity and mortality worldwide. Despite its prevalence, the development of novel antihypertensive...
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Immunological Indicators of Recurrent Pregnancy Loss: A Mendelian Randomization Study
Recurrent pregnancy loss (RPL) is thought to be related to maternal-fetal immune tolerance disorders. Immune monitoring of RPL patients mainly...
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Demographic, clinical, immunological, and molecular features of iranian national cohort of patients with defect in DCLRE1C gene
BackgroundDCLRE1C gene mutation leads to Artemis deficiency, a severe form of combined immunodeficiency (SCID). Impaired DNA repair and block in...
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The altered immunological status of children conceived by assisted reproductive technology
BackgroundWith the increased use of assisted reproductive technology (ART), assessing the potential health risks of children conceived on ART...
