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Sputum characteristics of patients with severe COVID-19: report of two cases with immunocytochemical detection of SARS-CoV-2 spike protein
Patients with SARS-CoV-2 infection and with severe COVID-19 often have multiple coinfections, and their treatment is challenging. Here, we performed...
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Systematic Review and Meta-Analysis to Identify the Immunocytochemical Markers Effective in Delineating Benign from Malignant Thyroid Lesions in FNAC Samples
Conventional cytology-based diagnosis for thyroid cancer is limited with more than 30–45% of nodules categorized as indeterminate, necessitating...
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Secretomes from Conventional Insemination and Intra-Cytoplasmic Sperm Injection Derived Embryos Differentially Modulate Endometrial Cells In Vitro
Conventional Insemination (CI) and Intra-Cytoplasmic Sperm Injection (ICSI) are routinely used insemination methods in clinical Assisted Reproductive...
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Power and optimal study design in iPSC-based brain disease modelling
Studies using induced pluripotent stem cells (iPSCs) are gaining momentum in brain disorder modelling, but optimal study designs are poorly defined....
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Immunocytochemistry on frozen-embedded cell block for the diagnosis of hematolymphoid cytology specimen: a straightforward alternative to the conventional cell block
Agarose-based cell block (CB) technique can be modified to be combined with the frozen section technique for the preparation of a high-quality...
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Osteogenic stimulation of osteoprogenitors by putamen ovi peptides and hyaluronic acid
Eggshell peptides (EP) majorly contribute to rapid bone building in chicks, wherefore this paper investigated their potential for stimulating...
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Evaluation of the effects of ethanol and mitomycin on survival of rat limbal stem cells: an in vitro study
PurposeEthanol and mitomycin C (MMC) are clinically used to treat corneal diseases such as LASEK and LASIK surgery. In this study, we investigated...
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Autoimmune processes in neurological patients are much more common than presently suspected
Autoimmune encephalitides are seldom diseases. How rare they actually are, however, is not known. The low incidence combined with the problematic...
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A reference center study in thyrotropin-secreting pituitary adenomas: clinicopathological, therapeutic and long-term follow-up outcomes
PurposeThis study aims to analyze the clinicopathological features, diagnostic steps, and therapeutic results of TSHomas and to reveal the effective...
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p38 Signaling Mediates Naringin-Induced Osteogenic Differentiation of Porcine Metanephric Mesenchymal Cells
ObjectiveTo explore the potential of metanephric mesenchymal cells (MMCs) for osteogenesis and naringin’s ability to enhance this process and its...
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Microglia-neuron interactions in prefrontal gray matter in schizophrenia: a postmortem ultrastructural morphometric study
This study addressed the question of whether the interaction between neurons and satellite microglia (SatMg) is abnormal in schizophrenia....
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Interobserver variability and accuracy of p16/Ki-67 dual immunocytochemical staining on conventional cervical smears
Backgroundp16/Ki-67 dual immunocytochemical staining (DS) has been proven as a sensitive and specific test for triage of HPV positive women with good...
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Comparative diagnostic performance of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) versus endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) for tissue sampling of solid pancreatic and non-pancreatic lesions without ROSE: a prospective multicenter study
Background and aimsEndoscopic ultrasound-guided tissue acquisition, including both fine-needle aspiration (EUS-FNA) and fine-needle biopsy (EUS-FNB),...
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LncRNA NONHSAT030515 promotes the chondrogenic differentiation of human adipose-derived stem cells via regulating the miR-490-5p/BMPR2 axis
BackgroundChondrogenic differentiation of human adipose-derived stem cells (hADSCs) is important for cartilage generation and degradation. LncRNAs...
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Image Analysis Using the Fluorescence Imaging of Nuclear Staining (FINS) Algorithm
Finding appropriate image analysis techniques for a particular purpose can be difficult. In the context of the analysis of immunocytochemistry...
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Cell composition at the vitreomacular interface in traumatic macular holes
PurposeTo describe characteristics of the vitreomacular interface (VMI) in traumatic macular holes (TMH) compared to idiopathic macular holes (IMH)...
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Myelin basic protein and neurofilament H in postmortem cerebrospinal fluid as surrogate markers of fatal traumatic brain injury
The aim of this study was to investigate if the biomarkers myelin basic protein (MBP) and neurofilament-H (NF-H) yielded informative value in...
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Micromorphological observation of HLE cells under knockdown of Fascin using LV-SEM
Liver cancer is one of the most prevalent cancers in Japan with hepatocellular carcinoma (HCC) as the major histological subtype. Successful novel...
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Δ3-tubulin impairs mitotic spindle morphology and increases nuclear size in pancreatic cancer cells
Cancer cell proliferation is affected by post-translational modifications of tubulin. Especially, overexpression or depletion of enzymes for...
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The diagnostic utility of cytology specimen in a case of EWSR1::NFATC2 sarcoma
EWSR1::NFATC2 sarcoma, a rare round cell sarcoma constituting the majority of EWSR1 ::non-ETS sarcomas, has recently been defined in the latest WHO...
