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A multicentric, randomized, controlled trial of yoga and fenugreek in prevention of type 2 diabetes mellitus: methodological details—the Indian Prevention of Diabetes Study (IPDS)
Preliminary studies have shown that yoga as well as fenugreek are beneficial in patients with type 2 diabetes mellitus (T2DM). This clinical trial is...
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How does academia respond to the burden of infectious and parasitic disease?
BackgroundAcademic research is one of the main avenues through which humans can fight the threat of infectious diseases. However, there have been...
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The impact of COVID-19 pandemic control on vaccine-preventable invasive bacterial diseases in Piedmont (Italy)
PurposeThe impact of SARS-CoV-2 pandemic on other pathogens is largely unknown. We aimed to compare the prevalence of vaccine-preventable invasive...
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Biomechanical comparison of different interspinous process devices in the treatment of lumbar spinal stenosis: a finite element analysis
BackgroundLumbar spinal stenosis (LSS) is a common disease among elderly individuals, and surgery is an effective treatment. The development of...
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Decompression Using Minimally Invasive Surgery for Lumbar Spinal Stenosis Associated with Degenerative Spondylolisthesis: A Review
Lumbar spinal stenosis (LSS), which often occurs concurrently with degenerative spondylolisthesis (DS), is a common disease in the elderly...
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Pneumococcal vaccine uptake among high-risk adults and children in Italy: results from the OBVIOUS project survey
BackgroundStreptococcus pneumoniae infections, including Invasive Pneumococcal Diseases (IPDs), pose a substantial public health challenge, causing...
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Is the interspinous process device safe and effective in elderly patients with lumbar degeneration? A systematic review and meta-analysis of randomized controlled trials
Background contextLumbar spinal stenosis is one of the most common diseases affecting the elderly that is characterized by the narrowing of the...
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Hospital admissions due to infectious and parasitic diseases in England and Wales between 1999 and 2019: an ecological study
BackgroundInfectious diseases continue to account for considerable illness and death worldwide, and emerging infectious diseases (EIDs) are a...
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Incidence of invasive pneumococcal disease in children with commercial insurance or Medicaid coverage in the United States before and after the introduction of 7- and 13-valent pneumococcal conjugate vaccines during 1998–2018
BackgroundInvasive pneumococcal disease (IPD) is a major cause of pediatric morbidity and mortality. Pneumococcal conjugate vaccines (PCVs) were...
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Cost-effectiveness evaluation of the 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine for children in Taiwan
BackgroundStreptococcus pneumoniae (S. pneumoniae) and non-typeable Haemophilus influenzae (NT Hi ) are substantial contributors to morbidity and...
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Knowledge, risk perception and uptake of COVID-19 vaccination among internally displaced persons in complex humanitarian emergency setting, Northeast Nigeria
BackgroundOwing to crowded and unsanitary conditions, internally displaced persons (IDPs) have an increased risk of COVID-19 infection. Adoption of...
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Limited protection of pneumococcal vaccines against emergent Streptococcus pneumoniae serotype 14/ST876 strains
PurposeStreptococcus pneumoniae (Spn) is a major cause of child death. We investigated the epidemiology of S. pneumoniae in a pediatric fever clinic...
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Co-infection with dual Streptococcus pneumoniae serotypes as a cause of pediatric bacterial meningitis in Iran: a multi-center cross-sectional study
BackgroundMeningitis is considered a life-threatening infection with high mortality all over the world. Hemophilus influenzae ( H. influenzae ) and Stre...
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Evaluation of the Lifetime Benefits of Metformin and SGLT2 Inhibitors in Type 2 Diabetes Mellitus Patients with Cardiovascular Disease: A Systematic Review and Two-Stage Meta-Analysis
BackgroundMetformin and sodium-glucose cotransporter-2 (SGLT2) inhibitors have demonstrated cardiovascular benefits but their comparative effects on...
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Clinical characteristics and risk factors for poor outcomes of invasive pneumococcal disease in pediatric patients in China
BackgroundInvasive pneumococcal disease (IPD) is a significant health concern in children worldwide. In this study, we aimed to analyze the clinical...
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Effectiveness of pneumococcal conjugate vaccination against invasive pneumococcal disease among children with and those without HIV infection: a systematic review and meta-analysis
BackgroundHIV-infected children are at a higher risk of Invasive Pneumococcal Disease (IPD) and its mortality, even in the era of antiretroviral...
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Intraperitoneal prophylactic drain after pancreaticoduodenectomy: an Italian survey
Intraperitoneal prophylactic drain (IPD) use in pancreaticoduodenectomy (PD) is still controversial. A survey was designed to investigate surgeons’...
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Touch imprint cytology is useful for the intraoperative pathological diagnosis of PitNETs’ surgical margins
Touch imprint cytology (TIC) and frozen section (FS) procedures are essential for intraoperative pathological diagnosis (IPD). They are invaluable...
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Axial loading during MRI reveals insufficient effect of percutaneous interspinous implants (Aperius™ PerCLID™) on spinal canal area
PurposeTo evaluate the effect on the spinal canal at the treated and adjacent level(s), in patients treated for lumbar spinal stenosis (LSS) with...