Search
Search Results
-
Prevalence of hearing impairment in neonatal encephalopathy due to hypoxia-ischemia: a systematic review and meta-analysis
BackgroundThis systematic review was undertaken to estimate the overall prevalence of hearing impairment in survivors of neonatal HIE.
Methods ...
-
Rectal temperature after hypoxia-ischemia predicts white matter and cortical pathology in the near-term ferret
BackgroundNeonatal encephalopathy (NE) remains a common cause of infant morbidity and mortality. Neuropathological corollaries of NE associated with...
-
Regional variability in therapeutic hypothermia eligibility criteria for neonatal hypoxic-ischemic encephalopathy
AbstractEarly induced therapeutic hypothermia represents the cornerstone treatment in neonates with probable hypoxic-ischemic encephalopathy. The...
-
Therapeutic hypothermia modulates the neurogenic response of the newborn piglet subventricular zone after hypoxia-ischemia
BackgroundNeuroprotection combined with neuroregeneration may be critical for optimizing functional recovery in neonatal encephalopathy. To...
-
-
Multifaceted functions of Drp1 in hypoxia/ischemia-induced mitochondrial quality imbalance: from regulatory mechanism to targeted therapeutic strategy
Hypoxic-ischemic injury is a common pathological dysfunction in clinical settings. Mitochondria are sensitive organelles that are readily damaged...
-
Hypothermia increases cold-inducible protein expression and improves cerebellar-dependent learning after hypoxia ischemia in the neonatal rat
BackgroundHypoxic ischemic encephalopathy remains a significant cause of developmental disability.
1 ,2 The standard of care for term infants is...
-
Hypoxia–ischemia-mediated effects on neurodevelopmentally regulated cold-shock proteins in neonatal mice under strict temperature control
BackgroundNeonates have high levels of cold-shock proteins (CSPs) in the normothermic brain for a limited period following birth. Hypoxic–ischemic...
-
Remote ischemic postconditioning for neuroprotection after newborn hypoxia–ischemia: systematic review of preclinical studies
BackgroundHypoxic–ischemic encephalopathy (HIE) is a major contributor to death and disability worldwide. Remote ischemic postconditioning (RIPC) may...
-
Neonatal hypoxia ischemia redistributes L1 cell adhesion molecule into rat cerebellar lipid rafts
BackgroundHypoxic–ischemic encephalopathy (HIE) is a devastating disease with lifelong disabilities. Hypothermia is currently the only treatment. At...
-
Neuropsychological, neuroimaging and autopsy findings of butane encephalopathy
BackgroundButane is an aliphatic hydrocarbon used in various commercial products. While numerous reports of sudden cardiac-related deaths from butane...
-
COHESION: a core outcome set for the treatment of neonatal encephalopathy
BackgroundHeterogeneity in outcomes reported in trials of interventions for the treatment of neonatal encephalopathy (NE) makes evaluating the...
-
Prognostic value of serum high-mobility group box 1 in neonates with neonatal encephalopathy
BackgroundThis study aimed to investigate the diagnostic potential of serum high-mobility group box 1 (HMGB1) in neonatal encephalopathy (NE).
...
-
The spectrum of sepsis-associated encephalopathy: a clinical perspective
Sepsis-associated encephalopathy is a severe neurologic syndrome characterized by a diffuse dysfunction of the brain caused by sepsis. This review...
-
Standardizing neonatal hypoxic ischemic encephalopathy evaluation and documentation practices
BackgroundInfants at risk for hypoxic ischemic encephalopathy (HIE) require a time sensitive evaluation and decision-making regarding treatment with...
-
FGF21 modulates hippocampal cold-shock proteins and CA2-subregion proteins in neonatal mice with hypoxia–ischemia
BackgroundFibroblast growth factor 21 (FGF21) is a neuroprotectant with cognitive enhancing effects but with poorly characterized mechanism(s) of...
-
Risk factors for infection and outcomes in infants with neonatal encephalopathy: a cohort study
BackgroundTo determine the association between early infection risk factors and short-term outcomes in infants with neonatal encephalopathy following...
-
Evaluation of heterogeneity in effect of therapeutic hypothermia by sex among infants with neonatal encephalopathy
BackgroundOur objective was to examine heterogeneity in the effect of therapeutic hypothermia by sex in infants with moderate or severe neonatal...
