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A comparison of the 33-item Hypomania Checklist with the 33-item Hypomania Checklist-external assessment for the detection of bipolar disorder in adolescents
BackgroundAdolescents with bipolar disorder (BD) are often misdiagnosed as having major depressive disorder (MDD), which delays appropriate treatment...
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Brain-based graph-theoretical predictive modeling to map the trajectory of anhedonia, impulsivity, and hypomania from the human functional connectome
Clinical assessments often fail to discriminate between unipolar and bipolar depression and identify individuals who will develop future (hypo)manic...
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Findings from a pilot open-label trial of N-acetylcysteine for the treatment of pediatric mania and hypomania
BackgroundPediatric bipolar disorder is a highly prevalent and morbid disorder and is considered a prevalent public health concern. Currently...
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Impact of modification to DSM-5 criterion A for hypomania/mania in newly diagnosed bipolar patients: findings from the prospective BIO study
BackgroundDSM-IV states that criterion A for diagnosing hypomania/mania is mood change. The revised DSM-5 now states that increased energy or...
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A Review of Antidepressant-Associated Hypomania in Those Diagnosed with Unipolar Depression—Risk Factors, Conceptual Models, and Management
Purpose of ReviewThe nosology and management of antidepressant-associated hypomania (AAH) in the treatment of unipolar depression requires...
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Empirically driven transdiagnostic stages in the development of mood, anxiety and psychotic symptoms in a cohort of youth followed from birth
Staging models with transdiagnostic validity across mood, psychotic, and anxiety disorders could advance early intervention efforts as well as our...
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Altered patterns of central executive, default mode and salience network activity and connectivity are associated with current and future depression risk in two independent young adult samples
Neural markers of pathophysiological processes underlying the dimension of subsyndromal-syndromal-level depression severity can provide objective,...
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A pilot trial of quetiapine, lithium, or placebo added to divalproex sodium for hypomanic or manic episodes in ambulatory adults with bipolar I disorder
BackgroundMany patients with bipolar I disorder do not respond to monotherapy treatment with mood-stabilizing medications, and combination regimens...
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Effects and safety of transcranial direct current stimulation on multiple health outcomes: an umbrella review of randomized clinical trials
Transcranial direct current stimulation (tDCS), which delivers a direct current to the brain, emerged as a non-invasive potential therapeutic in...
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Accuracy of the Arabic HCL - 32 and MDQ in detecting patients with bipolar disorder
BackgroundStudies about the two most used and validated instruments for the early detection of Bipolar Disorder (BD), the 32 - item Hypomania...
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Assessing anxiety among adolescents in Hong Kong: psychometric properties and validity of the Generalised Anxiety Disorder-7 (GAD-7) in an epidemiological community sample
BackgroundThe development of a valid and simple-to-use self-administered tool in Asian adolescents for clinical screening and intervention remains...
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Differences between bipolar disorder types 1 and 2 support the DSM two-syndrome concept
ObjectiveTo compare characteristics of bipolar disorder patients diagnosed as DSM-5 types I (BD-1) vs. II (BD-2).
MethodsWe compared descriptive,...
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Decreased dynamic variability of the cerebellum in the euthymic patients with bipolar disorder
BackgroundBipolar disorder (BD) is a complex mental illness characterized by different mood states, including depression, mania/hypomania, and...
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Dynamics of amygdala connectivity in bipolar disorders: a longitudinal study across mood states
Alterations in activity and connectivity of brain circuits implicated in emotion processing and emotion regulation have been observed during...
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Vocal features obtained through automated methods in verbal fluency tasks can aid the identification of mixed episodes in bipolar disorder
There is a lack of consensus on the diagnostic thresholds that could improve the detection accuracy of bipolar mixed episodes in clinical settings....
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Clinicodemographic correlates of psychotic features in bipolar disorder – a multicenter study in China
BackgroundPsychotic symptoms are prevalent in patients with bipolar disorder (BD). However, nearly all previous studies on differences in...
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‘Pediatric Bipolar Disorder’ rates are still lower than claimed: a re-examination of eight epidemiological surveys used by an updated meta-analysis
Background‘Pediatric bipolar disorder’ (PBD) is a controversial diagnosis with varying rates of clinical diagnosis. A highly cited meta-analysis (Van...
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Steroid-induced mania in a patient with previously well-controlled organic bipolar 1-like affective disorder secondary to acquired brain injury: case report and literature review
Steroid-induced neuropsychiatric sequelae are common, and pose significant risks to people usually receiving glucocorticoids in the context of...
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Late chronotype predicts more depressive symptoms in bipolar disorder over a 5 year follow-up period
BackgroundThere is increasing evidence that bipolar disorder is influenced by circadian timing, including the timing of sleep and waking activities....
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Decreased serum allopregnanolone and progesterone levels in male patients with bipolar disorder and their effects on cognitive functions
The progression of bipolar disorder (BD) is characterized by recurrent episodes of depression, mania, and hypomania, thus affecting the daily...
