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The effect of gonadotrophin-releasing hormone agonist versus human chorionic gonadotrophin trigger on pregnancy and neonatal outcomes in Letrozole-HMG IUI cycles
BackgroundGnRHa and hCG are both used for oocyte maturation and ovulation triggering. However, GnRHa have a shorter half-life than hCG, which leads...
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Freeze-all policy versus luteal phase support with low dose of human chorionic gonadotrophin for high-responder patients undergoing intracytoplasmic sperm injection on pregnancy outcomes: a retrospective cohort observational study
BackgroundThe literature has always controversies on the use of freeze-all policy in high-responder women performing intracytoplasmic sperm...
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Influence of human chorionic gonadotrophin during ovarian stimulation: an overview
It is widely known that luteinising hormone (LH) and human chorionic gonadotrophin (hCG) are integral in the female reproductive lifecycle. Due to...
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Value of endometrial thickness change after human chorionic gonadotrophin administration in predicting pregnancy outcome following fresh transfer in vitro fertilization cycles
PurposeTo study whether the change of endometrial thickness (EMT) between the day of human chorionic gonadotrophin (hCG) administration and the day...
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Progestin-primed ovarian stimulation protocol with or without clomiphene citrate for poor ovarian responders: a retrospective cohort study
ObjectiveTo explore the efficacy of progestin-primed ovarian stimulation (PPOS) combined with clomiphene citrate (CC) versus PPOS protocol used alone...
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Low-dose human menopausal gonadotrophin versus natural cycles in intrauterine insemination for subfertile couples with regular menstruation
BackgroundWomen with irregular menstruation should be considered to benefit from the ovarian stimulation. However, most literature did not separate...
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Metaphase-II oocyte competence is unlinked to the gonadotrophins used for ovarian stimulation: a matched case–control study in women of advanced maternal age
PurposeAn impact of different gonadotrophins selection for ovarian stimulation (OS) on oocyte competence has yet to be defined. In this study, we...
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Human Menopausal Gonadotropin Commenced on Early Follicular Period Increases Live Birth Rates in POSEIDON Group 3 and 4 Poor Responders
Human menopausal gonadotropin (hMG) has LH activity, and it may have beneficial effects in terms of oocyte quality and endometrial receptivity...
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Human metaphase II oocytes with narrow perivitelline space have poor fertilization, developmental, and pregnancy potentials
PurposeTo analyze the fertilization, developmental, and pregnancy potentials in oocytes with narrow perivitelline space.
MethodsPerivitelline space...
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The utility of human two plus one small pronucleated zygotes (2.1PN) based on clinical outcomes and the focused ploidy analysis
PurposeAre human embryos arising from two plus one small pronucleated zygotes, called 2.1 pronuclei (PN), clinically useful?
MethodsIn a...
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Effect of basal serum testosterone level on the ovarian response and the cumulative live birth rate in infertile women undergoing in vitro fertilization
PurposeTo evaluate the effect of basal serum testosterone levels on the ovarian response and the cumulative live birth rate of infertile women...
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Secrets Within: Unraveling the Intriguing Plot of an Adenocarcinoma in a Mature Ovarian Teratoma
A 52-year-old post-menopausal woman presented with abdominal distention and pain for 6 months. Imaging suggested ovarian cystadenocarcinoma, but...
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The therapeutic effects of rFSH versus uFSH/uHMG on ovarian stimulation in women undergoing assisted reproductive technology: a meta-analysis of randomized controlled trials
PurposeThis systematic review and meta-analysis aimed to compare the therapeutic effects of rFSH versus uFSH/uHMG on ovarian stimulation in women...
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Smooth endoplasmic reticulum cluster presence does not affect embryo ploidy
PurposeWe examined the impacts of the smooth endoplasmic reticulum cluster (sERC) presence on embryonic development and blastocyst ploidy.
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Myostatin: a multifunctional role in human female reproduction and fertility – a short review
Myostatin (MSTN) is member of the transforming growth factor β (TGF-β) superfamily and was originally identified in the musculoskeletal system as a...
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Advances in clinical applications of kisspeptin-GnRH pathway in female reproduction
BackgroundKisspeptin is the leading upstream regulator of pulsatile and surge Gonadotrophin-Releasing Hormone secretion (GnRH) in the hypothalamus,...
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Embryo Culture Medium Has No Impact on Mosaicism Rates: a Sibling Oocyte Study
Human embryos cultured in vitro can contain two or more cytogenetically distinct cell lineages known as “chromosomal mosaicism”. Since mosaicism is...
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Down-regulation of long non-coding RNAs in reproductive aging and analysis of the lncRNA-miRNA-mRNA networks in human cumulus cells
PurposeLong non-coding RNAs (lncRNAs) control gene expression at multiple levels. By interacting with microRNAs (miRNAs), they regulate their mRNA...
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Gonadotropin releasing hormone (GnRH) antagonist administration to decrease the risk of ovarian hyperstimulation syndrome in GNRH agonist cycles triggered with human chorionic gonadotropin
PurposeIn Gonadotropin releasing hormone(GnRH) agonist IVF, after administration of human chorionic gonadotropin(HCG) triggering, there is a risk of...
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In Vitro Maturation, In Vitro Oogenesis, and Ovarian Longevity
This paper will review a remarkable new approach to in vitro maturation “IVM” of oocytes from ovarian tissue, based on our results with in vitro...
