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  1. Emerging roles of noncoding RNAs in human cancers

    Studies have found that RNA encoding proteins only account for a small part of the total number, most RNA is non-coding RNA, and non-coding RNA may...

    Shijie Wu, Yiwen Wu, ... **aoyan Yang in Discover Oncology
    Article Open access 13 July 2023
  2. Carcinogenic roles of MAFG-AS1 in human cancers

    The MAF bZIP transcription factor G-antisense RNA 1 (MAFG-AS1) is located on chromosome 17. MAFG-AS1 was upregulated in 15 human cancers. MAFG-AS1...

    Mohsen Ahmadi, Firouzeh Morshedzadeh, ... Soudeh Ghafouri-Fard in Clinical and Translational Oncology
    Article 23 June 2023
  3. Pan-cancer analysis combined with experiments predicts NNMT as a therapeutic target for human cancers

    The identification of effective therapeutic targets plays a pivotal role in advancing cancer treatment outcomes. We employed a comprehensive...

    Hua Huang, Lianchun Su, ... Jun Chen in Discover Oncology
    Article Open access 29 May 2024
  4. Circular RNAs-mediated angiogenesis in human cancers

    Circular RNAs (circRNAs) as small non-coding RNAs with cell, tissue, or organ-specific expression accomplish a broad array of functions in...

    Farhoodeh Ghaedrahmati, Ava Nasrolahi, ... Maryam Farzaneh in Clinical and Translational Oncology
    Article 11 April 2023
  5. New perspectives for targeting therapy in ALK-positive human cancers

    Anaplastic lymphoma kinase (ALK) is a member of the insulin receptor protein-tyrosine kinase superfamily and was first discovered in anaplastic...

    Simin Zhao, Jian Li, ... Zigang Dong in Oncogene
    Article 06 May 2023
  6. Association of Human Papillomavirus Infection with Tonsillar Cancers: A Systematic Review

    Vaccinations have shown a decrease in human papillomavirus (HPV) infection-related cervical cancer in women, but there has been a sharp rise in the...

    Sneha Sethi, Alana Shahin, Intisar Nuha Abd Rahim in Indian Journal of Otolaryngology and Head & Neck Surgery
    Article Open access 29 August 2023
  7. Human Papilloma Virus Related Cancers in People Living with HIV

    Purpose of Review

    The burden of HPV co-infection in people living with HIV is high leading to increase incidence of HPV-related malignancies....

    Nicola Squillace, Viola Cogliandro, ... Paolo Bonfanti in Current Infectious Disease Reports
    Article 30 June 2023
  8. Human papillomavirus infection and non-oropharyngeal head and neck cancers: an umbrella review of meta-analysis

    Objective

    The causative and prognostic roles of human papillomavirus (HPV) in non-oropharyngeal squamous cell carcinoma of the head and neck are...

    Fausto Petrelli, Elisa Dal Cin, ... Vincenzo Capriotti in European Archives of Oto-Rhino-Laryngology
    Article 22 May 2023
  9. Genome-wide enhancer RNA profiling adds molecular links between genetic variation and human cancers

    Background

    Dysregulation of enhancer transcription occurs in multiple cancers. Enhancer RNAs (eRNAs) are transcribed products from enhancers that play...

    Yi-Min Cai, Ze-Qun Lu, ... Jian-Bo Tian in Military Medical Research
    Article Open access 11 June 2024
  10. Prognostic and clinicopathologic significance of circZFR in multiple human cancers

    Background

    Abnormally expressed in diverse cancers, circZFR has been correlated with clinical outcomes of cancer patients. Aim of this meta-analysis...

    Zhongyue Liu, Wenchao Zhang, ... Zhihong Li in World Journal of Surgical Oncology
    Article Open access 26 August 2022
  11. A pan-cancer analysis for the oncogenic role of cyclin-dependent kinase inhibitor 1B in human cancers

    Background

    Human health and life are threatened by cancer with high morbidity and mortality worldwide. In many experiments, CDKN1B level is associated...

    Hao Huang, Duoliang Qiu, ... Fengyun Zhong in Discover Oncology
    Article Open access 11 July 2023
  12. eccDNAdb: a database of extrachromosomal circular DNA profiles in human cancers

    E xtra c hromosomal c ircular DNA ( eccDNA ) elements are circular DNA molecules that are derived from but are independent of chromosomal DNA. EccDNA is...

    Li Peng, Nan Zhou, ... **ao-Qing Yuan in Oncogene
    Article Open access 06 April 2022
  13. CYFIP2 serves as a prognostic biomarker and correlates with tumor immune microenvironment in human cancers

    Background

    The mechanisms whereby CYFIP2 acts in tumor development and drives immune infiltration have been poorly explored. Thus, this study aimed to...

    Qiliang Peng, Bixin Ren, ... Ye Tian in European Journal of Medical Research
    Article Open access 21 September 2023
  14. A combined analysis of multi-omics data reveals the prognostic values and immunotherapy response of LAG3 in human cancers

    Lymphocyte-activation gene 3 (LAG3) is a highly anticipated immune checkpoint in the context of cancer, exerting regulatory control over immune cell...

    **wu Peng, Zhihao Du, ... Zhiyang Zhou in European Journal of Medical Research
    Article Open access 19 December 2023
  15. Epidemiology of HPV-associated cancers past, present and future: towards prevention and elimination

    Cervical cancer is the first cancer deemed amenable to elimination through prevention, and thus lessons from the epidemiology and prevention of this...

    Talía Malagón, Eduardo L. Franco, ... Salvatore Vaccarella in Nature Reviews Clinical Oncology
    Article 17 May 2024
  16. The role of RNA modification in urological cancers: mechanisms and clinical potential

    RNA modification is a post-transcriptional level of regulation that is widely distributed in all types of RNAs, including mRNA, tRNA, rRNA, miRNA,...

    Xuming Zhou, Hezhen Zhu, ... Guoxi Zhang in Discover Oncology
    Article Open access 20 December 2023
  17. ARID1A in Gynecologic Precancers and Cancers

    The highest frequency of genetic alterations in the tumor suppressor ARID1A occurs in malignancies of the female reproductive tract. The prevalence...

    Jaida E. Morgan, Nishah Jaferi, ... Gloria S. Huang in Reproductive Sciences
    Article 13 May 2024
  18. Radiotherapy resistance: identifying universal biomarkers for various human cancers

    Radiotherapy (RT) is considered as a standard in the treatment of most solid cancers, including glioblastoma, lung, breast, rectal, prostate,...

    Irina Larionova, Militsa Rakina, ... Evgeny Denisov in Journal of Cancer Research and Clinical Oncology
    Article 03 February 2022
  19. Targeting DNA Damage Response Deficiency in Thoracic Cancers

    Thoracic cancers comprise non-small cell lung cancers (NSCLCs), small cell lung cancers (SCLCs) and malignant pleural mesotheliomas (MPM)....

    Aleksandra Bzura, Jake B. Spicer, ... Dean A. Fennell in Drugs
    Article 13 July 2024
  20. Antibody-Drug Conjugates in Gynecologic Cancers

    Antibody-drug conjugates (ADCs) are a novel class of targeted cancer therapies with the ability to selectively deliver a cytotoxic drug to a tumor...

    Mary Katherine Anastasio, Stephanie Shuey, Brittany A. Davidson in Current Treatment Options in Oncology
    Article 03 January 2024
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