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Spatial and temporal distribution of reported dengue cases and hot spot identification in Quezon City, Philippines, 2010–2017
BackgroundDengue remains a major public health problem in the Philippines, particularly in urban areas of the National Capital Region. Thematic...
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Hot spot imaging in cardiovascular diseases: an information statement from SNMMI, ASNC, and EANM
This information statement from the Society of Nuclear Medicine and Molecular Imaging, American Society of Nuclear Cardiology, and European...
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Big data- and artificial intelligence-based hot-spot analysis of COVID-19: Gauteng, South Africa, as a case study
The coronavirus disease 2019 (COVID-19) has developed into a pandemic. Data-driven techniques can be used to inform and guide public health decision-...
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Human papillomavirus (HPV) integration signature in cervical lesions: identification of MACROD2 gene as HPV hot spot integration site
BackgroundHigh-risk HPV is clearly associated with cervical cancer. Integration of HPV DNA into the host genome is considered a key event in driving...
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Research progress and hot spot analysis related to oxidative stress and osteoarthritis: a bibliometric analysis
BackgroundOsteoarthritis, a common degenerative osteochondral disease, has a close relationship between its mechanism of occurrence and oxidative...
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Identifying emerging hot spots of road traffic injury severity using spatiotemporal methods: longitudinal analyses on major roads in Ghana from 2005 to 2020
BackgroundAlthough road traffic injuries and deaths have decreased globally, there is substantial national and sub-national heterogeneity,...
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COVID-19 hot-spot strategy: a special innovation in pandemic response, Oyo State Nigeria
BackgroundCOVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has evolved into a pandemic. Oyo state, Nigeria with a...
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Hepatic “hot-spot” on angio-computed tomography: the role of inferior Sappey’s and ensiform veins
Hepatic “hot spots” in anterior paraumbilical hepatic segments of patients suffering from superior vena cava syndrome may be revealed by...
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Prognostic potential of automated Ki67 evaluation in breast cancer: different hot spot definitions versus true global score
PurposeThe proliferation-associated biomarker Ki67 has potential utility in breast cancer, including aiding decisions based on prognosis, but has...
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Ki-67 “hot spot” digital analysis is useful in the distinction of hepatic adenomas and well-differentiated hepatocellular carcinomas
This study aims to investigate the utility of digital protocols for Ki-67 immunohistochemistry quantitative analysis (“hot spot” method) in the...
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How to evaluate perfusion imaging in post-treatment glioma: a comparison of three different analysis methods
IntroductionDynamic susceptibility contrast (DSC) perfusion weighted (PW)-MRI can aid in differentiating treatment related abnormalities (TRA) from...
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Possible PKHD1 Hot-spot Mutations Related to Early Kidney Function Failure or Hepatofibrosis in Chinese Children with ARPKD: A Retrospective Single Center Cohort Study and Literature Review
PKHD1 mutations are generally considered to cause autosomal recessive polycystic kidney disease (ARPKD). ARPKD is a rare disorder and one of the most...
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Testing, diagnosis, and treatment following the implementation of a program to provide dried blood spot testing for HIV and hepatitis C infections: the NSW DBS Pilot
BackgroundDried blood spot (DBS) testing provides an alternative to phlebotomy and addresses barriers to accessing healthcare experienced by some key...
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Different responses of Japanese encephalitis to weather variables among eight climate subtypes in Gansu, China, 2005–2019
This study evaluated epidemic temporal aspects of Japanese encephalitis (JE) and investigated the weather threshold of JE response across eight...
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Identification of hot regions in hub protein–protein interactions by clustering and PPRA optimization
BackgroundProtein–protein interactions (PPIs) are the core of protein function, which provide an effective means to understand the function at cell...
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Impact of spot positional errors in robustly optimized intensity-modulated proton therapy plan of craniospinal irradiation
We investigated the influence of random spot positioning errors (SPEs) on dosimetric outcomes of robustly optimized intensity-modulated proton...
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The geno-spatio analysis of Mycobacterium tuberculosis complex in hot and cold spots of Guangxi, China
BackgroundAt present, there are few studies on polymorphism of Mycobacterium tuberculosis (Mtb) gene and how it affects the TB epidemic. This study...
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Enhancing Informal Social Controls to Reduce Crime: Evidence from a Study of Crime Hot Spots
There is growing evidence that crime is strongly concentrated in micro-geographic hot spots, a fact that has led to the wide-scale use of hot spots...
