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Hepatocellular Carcinoma
This open access book offers a comprehensive review of hepatocellular carcinoma (HCC) with a particular focus on the pathobiology and clinical... -
Atlas of Hepatocellular Carcinoma Pathology
This atlas is designed to be a user-friendly bench-side reference for pathology trainees and general pathologists in handling and interpreting... -
Implications of ultrasound-based deep learning model for preoperatively differentiating combined hepatocellular-cholangiocarcinoma from hepatocellular carcinoma and intrahepatic cholangiocarcinoma
ObjectivesThe current study developed an ultrasound-based deep learning model to make preoperative differentiation among hepatocellular carcinoma...
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High-intensity focused ultrasound treatment for hepatocellular carcinoma
High-intensity focused ultrasound (HIFU) represents a method employing high-intensity ultrasound energy to induce thermal ablation of cancerous...
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Cytoskeletal gene alterations linked to sorafenib resistance in hepatocellular carcinoma
BackgroundAlthough sorafenib has been consistently used as a first-line treatment for advanced hepatocellular carcinoma (HCC), most patients will...
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MARCH5 promotes hepatocellular carcinoma progression by inducing p53 ubiquitination degradation
BackgroundHuman MARCH5 is a mitochondria-localized E3 ubiquitin-protein ligase that is essential for the regulation of mitochondrial dynamics. A...
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Scientific Hepatectomy for Hepatocellular Carcinoma
With advances in imaging technology and surgical instruments, hepatectomy can be perfectly performed with technical precision for hepatocellular...
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Cyclovirobuxine D inhibits hepatocellular carcinoma growth by inducing ferroptosis of hepatocellular carcinoma cells
ObjectiveHepatocellular carcinoma (HCC) is one cancer with high death rates. Nowadays, there are no effective drugs to treat it. Cyclovirobuxine D...
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Sonic hedgehog hepatocellular adenoma: magnetic resonance imaging features and correlation with histology
ObjectivesSonic hedgehog hepatocellular adenoma (shHCA) is a new hepatocellular adenoma (HCA) subgroup characterized by high risk of hemorrhage....
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Hepatocellular Carcinoma: a Narrative Review on Current Knowledge and Future Prospects
Hepatocellular carcinoma is the fourth leading cause of cancer-related deaths worldwide and its associated mortality rate is expected to rise within...
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Strategic advancement of E3 ubiquitin ligase in the management of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) presents a significant global health challenge due to its high incidence, poor prognosis, and limited treatment...
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Cannonball Pulmonary Metastases as Initial Presentation of Hepatocellular Carcinoma: A Case Report and Literature Review
BackgroundHepatocellular carcinoma is a major public health problem, as is considered the fastest growing cause of cancer-related death. Cannonball...
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Mallory-Denk bodies and hepatocellular senescence: a causal relationship?
Mallory-Denk bodies (MDBs) are hepatocellular cytoplasmic inclusions, which occur in certain chronic liver diseases, such as alcohol-related (ASH)...
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A novel cholesterol metabolism-related ferroptosis pathway in hepatocellular carcinoma
BackgroundEmerging studies have reported the contribution of cholesterol to hepatocellular carcinoma (HCC) progression. However, the specific role...
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Combined hepatocellular-cholangiocarcinoma: from genesis to molecular pathways and therapeutic strategies
Hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) are the most common primary liver cancers. Little is known about the...
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ESR Essentials: diagnosis of hepatocellular carcinoma—practice recommendations by ESGAR
AbstractHepatocellular carcinoma (HCC) is the most common primary hepatic malignancy and a leading cause of cancer related death worldwide. Current...
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ASCO update: hepatocellular and cholangiocellular carcinoma
At ASCO 2022 several studies were presented. This short review is about hepatocellular carcinoma, and cholangiocellular carcinoma and trials like...
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Spontaneous Tumor Lysis Syndrome in a Case of Hepatocellular Carcinoma with Sarcomatoid Differentiation
Sarcomatoid hepatocellular carcinoma is a rare histologic variant of primary liver cancer comprising of malignant spindle cells and typical...
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Adjuvant and neoadjuvant immunotherapies in hepatocellular carcinoma
Liver cancer, specifically hepatocellular carcinoma (HCC), is the sixth most common cancer and the third leading cause of cancer mortality worldwide....
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Hepatic artery infusion chemotherapy for advanced hepatocellular carcinoma
Objective:This study’s purpose was to evaluate the response, safety and overall survival of trans-arterial infusion chemotherapy in patients with...