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Radioresistance or/and radiosensitivity of head and neck squamous cell carcinoma: biological angle
ObjectiveThis narrative review aimed to compile and summarize clinically relevant literature in radiation therapy and to discuss the potential in...
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Exploring the frontiers: tumor immune microenvironment and immunotherapy in head and neck squamous cell carcinoma
The global prevalence of head and neck malignancies positions them as the sixth most common form of cancer, with the head and neck squamous cell...
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A Survey of Human Papillomavirus and Epstein-Barr virus Immunohistochemical Status in Patients with Head and Neck Squamous Cell Carcinoma (HNSCC)
BackgroundHead and neck cancers are among the most prevalent cancers in the body. The aim of this study was to evaluate the expression of P16 and...
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Neoadjuvant Immunotherapy for Head and Neck Squamous Cell Carcinoma: Expecting Its Application in Temporal Bone Squamous Cell Carcinoma
Temporal bone malignant tumors are characterized by atypical clinical symptoms, and easy recurrence and metastasis. They account for 0.2% of head and...
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Definitive Radiotherapy in Locally Advanced Head and Neck Squamous Cell Cancer with Clinical Extranodal Extension
PurposeThe extranodal extension (ENE) in head and neck squamous cell carcinoma (HNSCC) is a potential poor prognostic factor. Clinical ENE (cENE) was...
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Kruppel-family zinc finger proteins as emerging epigenetic biomarkers in head and neck squamous cell carcinoma
BackgroundKrüppel-type zinc finger protein genes located on chromosome 19q13 are aberrantly hypermethylated with high frequency in all anatomic...
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A comprehensive prognostic score for head and neck squamous cancer driver genes and phenotype traits
BackgroundHead and neck squamous cancer (HNSCC) presents variable phenotype and progression features. Clinically applicable, high-accuracy...
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P4HA2 contributes to head and neck squamous cell carcinoma progression and EMT through PI3K/AKT signaling pathway
Head and neck squamous cell carcinoma (HNSCC) can be defined as a deadly illness with a dismal prognosis in advanced stages. Therefore, we seek to...
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The prognosis and treatment of newly diagnosed bone metastasis of head and neck squamous cell cancer: an analysis of racial disparity
ObjectiveThere is a lack of research investigating racial disparity in newly diagnosed head and neck squamous cell carcinoma with isolated bone...
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The prognostic value of lymphatic metastatic size in head and neck squamous cell carcinoma
BackgroundLymphatic metastatic size was proved to predict prognosis in different types of carcinomas, except in head and neck squamous cell carcinoma...
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Advances and residual knowledge gaps in the neck management of head and neck squamous cell carcinoma patients with advanced nodal disease undergoing definitive (chemo)radiotherapy for their primary
PurposeSubstantial changes have been made in the neck management of patients with head and neck squamous cell carcinomas (HNSCC) in the past century....
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The dual role of autophagy in HPV-positive head and neck squamous cell carcinoma: a systematic review
PurposeHuman papilloma virus (HPV)-positive head and neck squamous cell carcinoma (HNSCC) displays distinct epidemiological, clinical, and molecular...
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Cuproptosis-related gene subtypes predict prognosis in patients with head and neck squamous cell carcinoma
BackgroundHead and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide. A novel form of copper-dependent and reactive...
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Neoadjuvant programmed cell death 1 blockade combined with chemotherapy for locally advanced head and neck squamous cell carcinoma
PurposeAnatomical structures and organ preservation concepts of the head and neck are important for patients with locally advanced head and neck...
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Comparative Evaluation of Surgical Operability with and without Induction Chemotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma
To compare and evaluation of surgical operability with and without induction chemotherapy in locally advanced head and neck squamous cell carcinoma....
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Neoadjuvant chemoimmunotherapy shows major pathological response and low recurrence in head and neck squamous cell carcinoma
BackgroundThe study aimed to investigate the efficacy and survival outcomes of neoadjuvant chemotherapy combined with programmed cell death protein 1...
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Predictive value of tumor budding in head and neck squamous cell carcinoma: an update
Head and neck squamous cell carcinoma forms an anatomically and functionally complex group of malignancies. The significant local aggressiveness and...
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Mutant HRas Signaling and Rationale for Use of Farnesyltransferase Inhibitors in Head and Neck Squamous Cell Carcinoma
Head and neck squamous cell carcinomas (HNSCCs) are often associated with poor outcomes, due at least in part to the limited number of treatment...
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Essential news of current guidelines: head and neck squamous cell carcinoma
Squamous cell carcinoma of the head and neck (HNSCC) is the sixth most common cancer and accounts for 890.000 cases 450.000 deaths worldwide...
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Expansion of tumor-infiltrating lymphocytes from head and neck squamous cell carcinoma to assess the potential of adoptive cell therapy
BackgroundAdoptive transfer of in vitro expanded tumor-infiltrating lymphocytes (TILs) has been effective in regressing several types of malignant...
