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The Multiple Functions of HB-EGF in Female Reproduction and Related Cancer: Molecular Mechanisms and Targeting Strategies
Heparin-binding growth factor (HB-EGF) is a member of the epidermal growth factor (EGF) ligand family which has a crucial role in women’s health....
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lncRNA H-19 and miR-200a implication and frequency of lncRNA H-19 rs2170425 SNP in ulcerative colitis and Crohn’s disease
Inflammation’s impact on inflammatory bowel diseases is mostly due to altered non-coding RNA expression. This study aimed to explore the rs2107425...
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Usefulness of measuring fast valley height rate using high-performance liquid chromatography for variant hemoglobin, Hb A2-Niigata
We have reported cases of hemoglobin (Hb) A2-Niigata (δ1Val → Ala) with δ chain variant Hb and falsely high HbA1c levels. In subjects with Hb...
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Personalized colorectal cancer screening: study protocol of a mixed-methods study on the effectiveness of tailored intervals based on prior f-Hb concentration in a fit-based colorectal cancer screening program (PERFECT-FIT)
BackgroundIn 2014, the national population-based colorectal cancer (CRC) screening program was implemented in the Netherlands. Biennial fecal...
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HB-EGF-induced IL-8 secretion from airway epithelium leads to lung fibroblast proliferation and migration
BackgroundWe have reported that heparin-binding epidermal growth factor (HB-EGF) is increased in patients with chronic obstructive pulmonary disease...
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Native T1-map** as a predictor of progressive renal function decline in chronic kidney disease patients
BackgroundTo investigate the potential of Native T1-map** in predicting the prognosis of patients with chronic kidney disease (CKD).
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Risk factors of disease activity and renal damage in patients with systemic lupus erythematosus
PurposeTo evaluate the clinical features of patients with Systemic Lupus Erythematosus (SLE) and explore the risk factors of disease activity and...
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Carbon monoxide intoxication with a CO-Hb of 30% while smoking waterpipe: a case report
Carbon monoxide (CO) poisoning is a significant public health issue and a considerable economic burden in developed countries. While the majority of...
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Fetal hemodynamic changes and mitochondrial dysfunction in myocardium and brain tissues in response to anemia: a lesson from hemoglobin Bart’s disease
ObjectiveWhether or not the effects of anemia in the early phase, while the fetuses attempts to increase cardiac output to meet oxygen requirement in...
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Determination of birth prevalence of sickle cell disease using point of care test HemotypeSC™ at Rundu Hospital, Namibia
BackgroundSickle cell disease (SCD), a noncommunicable disease, has the greatest burden in sub-Saharan Africa. The majority of children (50–90%) with...
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Impact of hyperbilirubinemia associated acute kidney injury on chronic kidney disease after aortic arch surgery: a retrospective study with follow-up of 1-year
BackgroundHyperbilirubinemia (HB) is a serious complication in aortic arch surgery, which is associated with acute kidney injury (AKI). The...
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Association of the American Heart Association’s new “Life’s Essential 8” with all-cause mortality in patients with chronic kidney disease: a cohort study from the NHANES 2009–2016
BackgroundPeople with chronic kidney disease (CKD) are more likely to die prematurely, and this increased risk of death is primarily attributable to...
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Blunted cerebral hemodynamic responses to incremental exercise in patients with end-stage renal disease
PurposeThe aims of this study were to compare cerebral hemodynamics and maximal oxygen uptake ( V O 2peak ) in patients with end-stage renal disease...
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The rare hemoglobin variant Hb Mizuho: report of a Swiss family and literature review
Hb Mizuho is a very rare unstable hemoglobin; here, we describe the clinical history of three Swiss family members with Hb Mizuho together with a...
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Association between hemoglobin and chronic kidney disease progression: a secondary analysis of a prospective cohort study in Japanese patients
ObjectiveAnemia has been reported as a risk factor for chronic kidney disease (CKD) progression. However, there are still few studies examining the...
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Utility of Low-cost Paper Based Haemoglobin Solubility Test for the Rapid Diagnosis of Sickle Cell Disease
In this study, we describe and compare a simple, rapid, low cost, point-of-care diagnostic paper-based test for screening of sickle cell disease,...
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The association between hemoglobin level and sarcopenia in Chinese patients with Crohn’s disease
Sarcopenia and anemia are common complications in patients with Crohn’s Disease (CD). However, few studies have shown the association between...
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The relationship between disease-specific psychosocial stressors and depressive symptoms in Huntington’s disease
BackgroundHuntington’s disease (HD) is an inherited neurodegenerative disease involving motor abnormalities, cognitive decline, and psychological...
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MicroRNA and renal fibrosis in autosomal dominant polycystic kidney disease: a longitudinal study
BackgroundAutosomal dominant polycystic kidney disease (ADPKD) is a hereditary kidney disorder that may progress to kidney failure, accounting for...
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Infantile inflammatory bowel disease in three Syrian infants: a case series
BackgroundInflammatory bowel diseases, consisting of Crohn’s disease and ulcerative colitis, are chronic bowel relapsing inflammatory disorders....
