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Mechanism of anticancer effect of ETP-45658, a PI3K/AKT/mTOR pathway inhibitor on HT-29 Cells
The PI3K pathway plays a crucial role in tumor cell proliferation across various cancers, including colon cancer, making it a promising treatment...
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Anticancer activity of lycopene in HT-29 colon cancer cell line
An inverse association between serum lycopene levels and the risk of cancers has been pointed out by many prospective and retrospective...
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Campylobacter concisus from chronic inflammatory bowel diseases stimulates IL-8 production in HT-29 cells
The emerging pathogen Campylobacter concisus has been isolated from patients with gastrointestinal diseases; however, it is also present in the gut...
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Exploration of the aptitude to alleviate oxidative impairment and curb colorectal cancer manifestation by Nostoc calcicola in HT-29 adenocarcinoma cells
BackgroundMarine cyanobacteria have been known to contain several unique bioactive compounds which have different therapeutic potentials. The current...
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The potential therapeutic effect of klotho on cell viability in human colorectal adenocarcinoma HT-29 cells
Klotho is an anti-aging, anti-inflammator, and anti-oxidative protein and has been shown to important role in tumorigenesis, proliferation, survival,...
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Design and Characterization of Silver Nanoparticles of Different Species of Curcuma in the Treatment of Cancer Using Human Colon Cancer Cell Line (HT-29)
BackgroundCancer is a deadly disease responsible for worldwide mortality; usually, middle- and low-income countries have been more affected by cancer...
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Anticancer Effect of Sargassum oligocystom Hydroalcoholic Extract Against SW742, HT-29, WiDr, and CT-26 Colorectal Cancer Cell Lines and Expression of P53 and APC Genes
PurposeColorectal cancer (CRC) is the third most common cancer in the world, with enhancing morbidity and mortality each year. Due to the drug...
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Tumoricidal properties of thymoquinone on human colorectal adenocarcinoma cells via the modulation of autophagy
Colorectal cancer (CRC) is deadly anaplastic changes in the gastrointestinal tract with high-rate mortality. In recent years, the application of...
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Antitumor activity of the new tyrphostin briva against BRAFV600E-mutant colorectal carcinoma cells
Because of a reduced sensitivity of BRAF-mutant colorectal cancers to BRAF inhibitor treatment when compared with BRAF-mutant melanoma, it is...
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Proliferation Inhibitory Activity of Quinones from Blaps rynchopetera Defense Secretion on Colorectal Tumor Cells
ObjectiveTo explore the proliferation inhibitory effect of quinones from Blaps rynchopetera defense secretion on colorectal tumor cell lines.
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The pathogenicity of vancomycin-resistant Enterococcus faecalis to colon cancer cells
BackgroundThe aim of this study was to investigate the pathogenicity of vancomycin-resistant Enterococcus faecalis (VREs) to human colon cells in...
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The in vitro treatment of mesenchymal stem cells for colorectal cancer cells
Colorectal cancer is the most common tumor of the gastrointestinal system. The conventional treatment options for colorectal cancer are troublesome...
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In vitro siRNA-mediated GPX4 and AKT1 silencing in oxaliplatin resistance cancer cells induces ferroptosis and apoptosis
Oxaliplatin is a member of platinum-based chemotherapy drugs frequently used in colorectal cancer (CRC). However, resistance to oxaliplatin causes...
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N-methyl-D-aspartate receptors and thymoquinone induce apoptosis and alteration in mitochondria in colorectal cancer cells
Colon cancer is on the rise in both men and women. In addition to traditional treatment methods, herbal treatments from complementary and alternative...
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Evaluation of the Anti-cancer Effect of Syzygium cumini Ethanolic Extract on HT-29 Colorectal Cell Line
IntroductionGLOBOCAN 2018 data indicates the incidence and mortality of colorectal cancer that is the third lethal and fourth most diagnosed cancer...
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Radiosensitizing effects of trabectedin on human A549 lung cancer cells and HT-29 colon cancer cells
Background and Purpose Trabectedin is a unique alkylating agent with promising effects against a range of solid tumors. In this study, we aimed to...
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Combination of resveratrol and BIBR1532 inhibits proliferation of colon cancer cells by repressing expression of LncRNAs
Colorectal cancer (CRC) is the third most common cancer worldwide. The development of tumor drug resistance is observed in the treatment of CRC....
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Enterotoxigenic Bacteroides fragilis activates IL-8 expression through Stat3 in colorectal cancer cells
BackgroundEnterotoxigenic Bacteroides fragilis (ETBF) has been implicated in colorectal carcinogenesis through the actions of its toxin, B. fragilis ...
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Anticancer properties of red beetroot hydro-alcoholic extract and its main constituent; betanin on colorectal cancer cell lines
Colorectal cancer (CRC) is the third most common type of cancer worldwide. Red beetroot ( Beta vulgaris ) contains Betanin as its major betacyanin,...
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An effective treatment approach of liposomally encapsulated metformin in colon cancer
Metformin is a drug that is widely used in the treatment of type-2 diabetes and its anticarcinogenic effect has been detected in many studies since...
