Search
Search Results
-
Protease and gag diversity and drug resistance mutations among treatment-naive Mexican people living with HIV
IntroductionIn Mexico, HIV genoty** is performed in people living with HIV (PLWH) failing their first-line antiretroviral (ARV) regimen; it is not...
-
HIV-1-related factors interact with p53 to influence cellular processes
Human immunodeficiency virus type 1 (HIV-1) is the primary epidemic strain in China. Its genome contains two regulatory genes ( tat and rev ), three...
-
HIV-1 Myeloid Reservoirs — Contributors to Viral Persistence and Pathogenesis
Purpose of ReviewHIV reservoirs are the main barrier to cure. CD4+ T cells have been extensively studied as the primary HIV-1 reservoir. However,...
-
HIV Reservoir: How to Measure It?
Purposeof ReviewIn the current quest for a complete cure for HIV/AIDS, the persistence of a long-lived reservoir of cells carrying...
-
The U.S. Global Gag Rule in Ethiopia: a foreign policy challenging domestic sexual and reproductive health and rights gains
BackgroundEthiopia’s government and civil society have driven crosscutting initiatives in the last 15 years to improve sexual and reproductive health...
-
HIV Pre-Exposure Prophylaxis: New and Upcoming Drugs to Address the HIV Epidemic
Human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP) provides a critical intervention toward ending the HIV epidemic and protecting...
-
CRISPR/Cas9: a tool to eradicate HIV-1
The development of antiretroviral therapy (ART) has been effective in suppressing HIV replication. However, severe drug toxicities due to the therapy...
-
Immunogenicity of personalized dendritic-cell therapy in HIV-1 infected individuals under suppressive antiretroviral treatment: interim analysis from a phase II clinical trial
BackgroundWe developed a personalized Monocyte-Derived Dendritic-cell Therapy (MDDCT) for HIV-infected individuals on suppressive antiretroviral...
-
Specific quantification of inducible HIV-1 reservoir by RT-LAMP
BackgroundStrategies toward HIV-1 cure aim to clear, inactivate, reduce, or immunologically control the virus from a pool of latently infected cells...
-
Preservation of lymphocyte functional fitness in perinatally-infected and treated HIV+ pediatric patients displaying sub-optimal viral control
BackgroundHost–pathogen dynamics associated with HIV infection are quite distinct in children versus adults. We interrogated the functional fitness...
-
Learning from Persistent Viremia: Mechanisms and Implications for Clinical Care and HIV-1 Cure
Purpose of ReviewIn this review, we discuss what persistent viremia has taught us about the biology of the HIV-1 reservoir during antiretroviral...
-
More than the Infinite Monkey Theorem: NHP Models in the Development of a Pediatric HIV Cure
Purpose of ReviewAn HIV cure that eliminates the viral reservoir or provides viral control without antiretroviral therapy (ART) is an urgent need in...
-
Genetic characterization of HIV-1 viruses among cases with antiretroviral therapy failure in Suzhou City, China
BackgroundThis retrospective study aimed to characterize the distribution of HIV-1 genotypes and the prevalence of drug resistance mutations in...
-
IFNα induces CCR5 in CD4+ T cells of HIV patients causing pathogenic elevation
BackgroundAmong people living with HIV, elite controllers (ECs) maintain an undetectable viral load, even without receiving anti-HIV therapy. In...
-
Postabortion and safe abortion care coverage, capacity, and caseloads during the global gag rule policy period in Ethiopia and Uganda
BackgroundAbortion-related complications contribute to preventable maternal mortality, accounting for 9.8% of maternal deaths globally, and 15.6% in...
-
Epidemiological and viral characteristics of undiagnosed HIV infections in Botswana
BackgroundHIV-1 is endemic in Botswana. The country’s primary challenge is identifying people living with HIV who are unaware of their status. We...
-
The AIDS and Cancer Specimen Resource (ACSR): HIV malignancy specimens and data available at no cost
The goal of the AIDS and Cancer Specimen Resource (ACSR) is to play a major role in the advancement of HIV/AIDS cancer-related research/treatment by...
-
Genetic Appraisal of RAAS-Associated SNPs: REN (rs16853055), AGT (rs3789678) and ACE (rs4305) in Preeclamptic Women Living with HIV Infection
Purpose of ReviewThe primary goal of this review article was to determine whether the three RAAS-associated SNPs, Renin-rs16853055, AGT-rs3789678 and...
-
Update on Central Nervous System Effects of HIV in Adolescents and Young Adults
Purpose of Review.Behaviorally acquired (non-perinatal) HIV infection during adolescence and young adulthood occurs in the midst of key brain...
-
Evaluation of Geenius HIV-1/2 Confirmatory Assay for the confirmatory and differential diagnosis of HIV-1/HIV-2 in Japan and reliability of the Geenius Reader in the diagnosis of HIV-2
BackgroundNEW LAV BLOT I and II (LAV I and LAV II), they were only option for human immunodeficiency virus (HIV) confirmatory test, following HIV...