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Growth Hormone and Prolactin Co-secreting Pituitary Adenoma: a Case Report and Review of Literature
Co-secreting growth hormone and prolactin pituitary adenomas, which comprise a considerable portion of all growth hormone-secreting adenomas, can be...
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Global changes in chromatin accessibility and transcription in growth hormone-secreting pituitary adenoma
PurposeGrowth hormone-secreting pituitary adenoma (GHPA) is an insidious disease with persistent hypersecretion of growth hormone and insulin-like...
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Giant growth hormone-secreting pituitary adenomas from the endocrinologist’s perspective
ObjectivesSince giant (≥40 mm) GH-secreting pituitary adenomas are rarely encountered, data on their characteristics and treatment outcomes are...
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Clinical characteristics and therapeutic outcomes of acromegalic patients with giant growth hormone-secreting pituitary adenomas: a single-center study of 67 cases
PurposeAcromegalic patients with giant growth hormone-secreting pituitary adenomas (GHPAs) (≥ 40 mm) are relatively rare, and their clinical...
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Vascular anomalies in patients with growth hormone-secreting pituitary adenomas: illustrative case report and systematic review of the literature
PurposeEndonasal resection is the first-line treatment for patients harboring growth hormone (GH)-secreting pituitary adenomas. The complexity of the...
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Cost-effectiveness of direct surgery versus preoperative octreotide therapy for growth-hormone secreting pituitary adenomas
PurposeThe objective of this study was to compare the cost-effectiveness of preoperative octreotide therapy followed by surgery versus the standard...
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Pituitary adenoma or neuroendocrine tumour: the need for an integrated prognostic classification
In the 2022 fifth edition of the WHO Classification of Endocrine Tumours and of Central Nervous System Tumours, pituitary adenomas are reclassified...
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Current status of artificial intelligence technologies in pituitary adenoma surgery: a sco** review
PurposePituitary adenoma surgery is a complex procedure due to critical adjacent neurovascular structures, variations in size and extensions of the...
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Antiplatelet and anticoagulation therapy and the risk of pituitary apoplexy in pituitary adenoma patients
PurposePituitary apoplexy can be a life threatening and vision compromising event. Antiplatelet and anticoagulation use has been reported as a...
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Imaging of pituitary tumors: an update with the 5th WHO Classifications—part 1. Pituitary neuroendocrine tumor (PitNET)/pituitary adenoma
The pituitary gland is the body’s master gland of the endocrine glands. Although it is a small organ, many types of tumors can develop within it. The...
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Celastrol Induces Apoptosis and Autophagy via the AKT/mTOR Signaling Pathway in the Pituitary ACTH-secreting Adenoma Cells
ObjectivePituitary adrenocorticotropic hormone (ACTH)-secreting adenoma is a relatively intractable endocrine adenoma that can cause a range of...
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Clinical characteristics and outcomes of patients with TSH-secreting pituitary adenoma and Graves’ disease - a case report and systematic review
BackgroundCoexistence of TSH-secreting pituitary adenoma (TSHoma) and Graves’ disease (GD) is rare and complicates the management decision.
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Reported baseline variables in transsphenoidal surgery for pituitary adenoma over a 30 year period: a systematic review
PurposeHeterogeneous reporting in baseline variables in patients undergoing transsphenoidal resection of pituitary adenoma precludes meaningful...
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Ectopic invasive ACTH-secreting pituitary adenoma mimicking chordoma: a case report and literature review
BackgroundEctopic pituitary adenoma (EPA) is defined as a special type of pituitary adenoma that originates outside of the sellar region, is extra-...
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Diagnosis and management of prolactin-secreting pituitary adenomas: a Pituitary Society international Consensus Statement
This Consensus Statement from an international, multidisciplinary workshop sponsored by the Pituitary Society offers evidence-based graded consensus...
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Clinical characteristics and treatment strategies for pituitary adenoma associated with intracranial aneurysm
BackgroundThis study aimed to investigate clinical features and treatment strategies for intracranial aneurysm (IA) associated with pituitary adenoma...
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High prevalence of morphometric vertebral fractures opportunistically detected on thoracic radiograms in patients with non-functioning pituitary adenoma
PurposeVertebral fractures (VFs), the hallmark of skeletal fragility, have been reported as an emerging complication in patients with pituitary...
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Validation of the anterior skull base questionnaire 35 in endoscopic pituitary adenoma surgery
Patient quality of life (QOL) is an important metric of surgical success. To guide therapeutic advances in pituitary adenoma surgery, a validated,...
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Concurrent mutations of germline GPR101 and somatic USP8 in a pediatric giant pituitary ACTH adenoma: a case report
BackgroundCushing’s disease (CD) is rare in pediatric patients. It is characterized by elevated plasma adrenocorticotropic hormone (ACTH) from...
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Improvement of metabolic syndrome and its components in patients who underwent transsphenoidal resection for pituitary adenoma
BackgroundPituitary adenomas (PA) are neoplasms of pituitary adenohypophyseal cell lineage, which are the third most common cause of brain tumors...
