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Showing 1-20 of 55 results
  1. NF-κB in biology and targeted therapy: new insights and translational implications

    NF-κB signaling has been discovered for nearly 40 years. Initially, NF-κB signaling was identified as a pivotal pathway in mediating inflammatory...

    Qing Guo, Yizi **, ... Jian Zhang in Signal Transduction and Targeted Therapy
    Article Open access 04 March 2024
  2. Pyoderma Gangrenosum: An Updated Literature Review on Established and Emerging Pharmacological Treatments

    Pyoderma gangrenosum is a rare inflammatory skin disease classified within the group of neutrophilic dermatoses and clinically characterized by...

    Carlo Alberto Maronese, Matthew A. Pimentel, ... Angelo Valerio Marzano in American Journal of Clinical Dermatology
    Article Open access 24 May 2022
  3. Pathogenesis of allergic diseases and implications for therapeutic interventions

    Allergic diseases such as allergic rhinitis (AR), allergic asthma (AAS), atopic dermatitis (AD), food allergy (FA), and eczema are systemic diseases...

    Ji Wang, Yumei Zhou, ... Qi Wang in Signal Transduction and Targeted Therapy
    Article Open access 24 March 2023
  4. Advancing Biologic Therapy for Refractory Autoimmune Hepatitis

    Biologic agents may satisfy an unmet clinical need for treatment of refractory autoimmune hepatitis. The goals of this review are to present the...

    Albert J. Czaja in Digestive Diseases and Sciences
    Article 11 February 2022
  5. Activation of immune signals during organ transplantation

    The activation of host’s innate and adaptive immune systems can lead to acute and chronic graft rejection, which seriously impacts graft survival....

    Qingwen Li, Peixiang Lan in Signal Transduction and Targeted Therapy
    Article Open access 11 March 2023
  6. New insights gained from cellular landscape changes in myocarditis and inflammatory cardiomyopathy

    Advances in the etiological classification of myocarditis and inflammatory cardiomyopathy (ICM) have reached a consensus. However, the mechanism of...

    Weiteng Wang, Hao Jia, ... Jiang** Song in Heart Failure Reviews
    Article 19 June 2024
  7. Clinical Management of Primary Biliary Cholangitis—Strategies and Evolving Trends

    PBC is a chronic progressive autoimmune disorder involving the destruction of intrahepatic small bile ducts, cholestasis, fibrosis, and ultimately...

    Lixia Gao, Li Wang, ... M. Eric Gershwin in Clinical Reviews in Allergy & Immunology
    Article 11 November 2019
  8. Pharmacotherapy for Neuromyelitis Optica Spectrum Disorders: Current Management and Future Options

    Neuromyelitis optica (NMO) is an inflammatory and demyelinating disease of the central nervous system. Although the prevalence of NMO is low, the...

    Nicolas Collongues, Estelle Ayme-Dietrich, ... Jérôme de Seze in Drugs
    Article 08 January 2019
  9. Virotherapy as Potential Adjunct Therapy for Graft-Vs-Host Disease

    Purpose of Review

    This review discusses the pathophysiology, risk factors, and the advances in the prevention or treatment of graft-vs-host disease...

    Nancy Y. Villa, Grant McFadden in Current Pathobiology Reports
    Article Open access 19 November 2018
  10. Clinical Pharmacokinetic and Pharmacodynamic Considerations in the Treatment of Inflammatory Bowel Disease

    According to recent clinical consensus, pharmacotherapy of inflammatory bowel disease (IBD) is, or should be, personalized medicine. IBD treatment is...

    Luc J. J. Derijks, Dennis R. Wong, ... Adriaan A. van Bodegraven in Clinical Pharmacokinetics
    Article 06 March 2018
  11. Abstracts

    Article 07 March 2020
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