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Mortality of type 2 diabetes in Germany: additional insights from Gompertz models
AimsThe Gompertz law of mortality proclaims that human mortality rates in middle to old ages grow log-linearly with age and this law has been...
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Incidence of infant mortality and its predictors in East Africa using Gompertz gamma shared frailty model
BackgroundGlobally, infant mortality is a major public health concern and a sensitive indicator of countries' socio-economic and health status....
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Incidence of neonatal mortality and its predictors among live births in Ethiopia: Gompertz gamma shared frailty model
BackgroundNeonatal mortality remains a serious public health concern in develo** countries including Ethiopia. Ethiopia is one of the countries...
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Demographic Indicators of Probability Models
Abstract —Describing mortality dynamics using average indicators without considering variability can yield average results, impeding the analysis of...
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Deep transfer learning with fuzzy ensemble approach for the early detection of breast cancer
Breast Cancer is a significant global health challenge, particularly affecting women with higher mortality compared with other cancer types. Timely...
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Pattern and trends of the total and age-specific fertility rates during 1990–2018 in Pakistan
BackgroundPakistan has an inadequate vital event registration system, leading to fewer than half of all births being registered, and this issue is...
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A parametric additive hazard model for time-to-event analysis
BackgroundIn recent years, the use of non- and semi-parametric models which estimate hazard ratios for analysing time-to-event outcomes is...
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Why too soon? Predictors of time to diabetic peripheral neuropathy among newly diagnosed diabetes mellitus patients: a multicenter follow-up study at health-care setting of Ethiopia
BackgroundDue to the rising number of diabetic patients, the burden of diabetic peripheral neuropathy (DPN) is clearly posing a major challenge to...
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Population Health Model Predicting the Long-Term Impact of Sotatercept on Morbidity and Mortality in Patients with Pulmonary Arterial Hypertension (PAH)
IntroductionPulmonary arterial hypertension (PAH) is a rare, progressive disease associated with significant morbidity and mortality. The phase 3...
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Impact of Extrapolation Model Choices on the Structural Uncertainty in Economic Evaluations for Cancer Immunotherapy: A Case Study of Checkmate 067
ObjectivesThe aim of this study was to compare the performance of different extrapolation modeling techniques and analyze their impact on structural...
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Post-surgery survival and associated factors for cardiac patients in Ethiopia: applications of machine learning, semi-parametric and parametric modelling
IntroductionLiving in poverty, especially in low-income countries, are more affected by cardiovascular disease. Unlike the developed countries, it...
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Assessing the joint prevalence of dementia and hearing loss in Scotland: a growth model for public health planning
AimData in Public Health studies often comes in mismatched age groups. This study investigated how mathematical modelling techniques could be used to...
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Cost-utility analysis of different venous access devices in breast cancer patients: a decision-based analysis model
BackgroundVenous access devices commonly used in clinical practice for long-term chemotherapy of breast cancer include central venous catheters...
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Education and medication use later in life and the role of intelligence
We investigate the association between education and disease-specific medications in old age, prescribed by medical doctors, accounting for...
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Development and Validation of the Life Expectancy Estimator for Older Adults with Diabetes (LEAD): the Diabetes and Aging Study
BackgroundEstimated life expectancy for older patients with diabetes informs decisions about treatment goals, cancer screening, long-term and...
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Infliximab versus ciclosporin in steroid resistant acute severe ulcerative colitis: a model-based cost-utility analysis of data from CONSTRUCT pragmatic trial
BackgroundThere is limited evidence in the literature on the long-term effectiveness and cost-effectiveness of treatments for Acute Severe Ulcerative...
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Informing Structural Assumptions for Three State Oncology Cost-Effectiveness Models through Model Efficiency and Fit
The characteristics and relative strengths and weaknesses of partitioned survival models (PSMs) and state transition models (STMs) for three state...
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Cost-effectiveness Analysis of Tisagenlecleucel Versus Blinatumomab in Children and Young Adults with Acute Lymphoblastic Leukemia: Partitioned Survival Model to Assess the Impact of an Outcome-Based Payment Arrangement
ObjectiveThis research assesses the impact of an outcome-based payment arrangement (OBA) linking complete remission (CR) to survival as a means of...
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Evolution of serum progesterone levels in the very early luteal phase of stimulated IVF/ICSI cycles post hCG trigger: a proof of concept study
BackgroundStudies have suggested that controlled ovarian hyperstimulation adversely affects endometrial receptivity due to advanced endometrial...
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A progressive three-state model to estimate time to cancer: a likelihood-based approach
BackgroundTo optimize colorectal cancer (CRC) screening and surveillance, information regarding the time-dependent risk of advanced adenomas (AA) to...
