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Glioma
Gliomas are primary brain tumours that are thought to develop from neural stem or progenitor cells that carry tumour-initiating genetic alterations....
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Thrombospondin-2 promotes the proliferation and migration of glioma cells and contributes to the progression of glioma
BackgroundGliomas, especially high-grade gliomas, are highly malignant with a poor prognosis. Although existing treatments have improved the survival...
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Perioperative Neurocognitive Function in Glioma Surgery
Purpose of ReviewThis review provides a concise overview of the recent literature regarding preoperative and postoperative neurocognitive functioning...
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CPLX2 is a novel tumor suppressor and improves the prognosis in glioma
BackgroundGlioma is a type of malignant cancer that affect the central nervous system. New predictive biomarkers have been investigated in recent...
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Cellular senescence in glioma
IntroductionGlioma is the most common primary brain tumor and is often associated with treatment resistance and poor prognosis. Standard treatment...
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Deciphering glioma epitranscriptome: focus on RNA modifications
Gliomas are highly malignant tumors accounting for the majority of brain neoplasms. They are characterized by nuclear atypia, high mitotic rate and...
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Radiotherapy for pediatric low-grade glioma
IntroductionRadiotherapy is a highly effective treatment for pediatric low-grade glioma, serving as the standard for evaluating progression-free and...
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Liquid biomarkers in glioma
An ideal biomarker must meet several parameters to enable its successful adoption; however, the nature of glioma makes it challenging to discover...
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Prognostic factors analysis of diffuse midline glioma
PurposeThis study retrospectively analyzes cases of diffuse midline glioma treated with radiotherapy, with the aim of investigating the prognosis of...
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Prognostic values and immune infiltration of KLF15, AQP7, AGPAT9 in glioma and glioblastoma
BackgroundsThe overall survival of patients with lower-grade gliomas and glioblastoma varies greatly. No reliable or existing procedures can...
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Recent Update on PET/CT Radiotracers for Imaging Cerebral Glioma
Positron emission tomography/computed tomography (PET/CT) has dramatically altered the landscape of noninvasive glioma evaluation, offering...
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HOXD9 is a potential prognostic biomarker involved in immune microenvironment of glioma
BackgroundGlioma is the prevailing malignant tumor affecting the brain and central nervous system, constituting over 80% of all malignant brain...
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Hypoxic microenvironment-induced exosomes confer temozolomide resistance in glioma through transfer of pyruvate kinase M2
ObjectiveGlioma, a malignant primary brain tumor, is notorious for its high incidence rate. However, the clinical application of temozolomide (TMZ)...
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Association between viral infections and glioma risk: a two-sample bidirectional Mendelian randomization analysis
BackgroundGlioma is one of the leading types of brain tumor, but few etiologic factors of primary glioma have been identified. Previous observational...
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Glioma-associated macrophages: unraveling their dual role in the microenvironment and therapeutic implications
Glioblastoma (GBM) is a malignant brain glioma characterized by a high number of tumor-associated macrophages (TAMs) within its tissues. These TAMs...
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Ganciclovir as a potential treatment for glioma: a systematic review and meta-analysis
BackgroundGlioma is a challenging malignant tumor with a low survival rate and no effective treatment. Recently, ganciclovir, an antiviral drug,...
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Caveolin-1 promotes glioma progression and maintains its mitochondrial inhibition resistance
BackgroundGlioma is a lethal brain cancer and lacking effective therapies. Challenges include no effective therapeutic target, intra- and...
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ZNF384 transcriptionally activated MGST1 to confer TMZ resistance of glioma cells by negatively regulating ferroptosis
BackgroundDrug resistance is one of the major reasons of the poor prognosis and recurs frequently in glioma. Ferroptosis is considered to be a new...
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HIF-1α facilitates glioma proliferation and invasion by activating pyroptosis signaling axis
BackgroundHIF-1α is thought to be a novel regulator which contributes to carcinogenesis. However, the mechanism underlying the effect of HIF-1α in...
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Prognostic value of pretreatment lymphocyte-to-monocyte ratio in patients with glioma: a meta-analysis
BackgroundMany studies have explored the prognostic role of the lymphocyte-to-monocyte ratio (LMR) in patients with glioma, but the results have been...
