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Effects of garlic supplementation on components of metabolic syndrome: a systematic review, meta-analysis, and meta-regression of randomized controlled trials
BackgroundGarlic (Allium sativum), the underground bulb of the Allium genus , has been consumed on Earth for thousands of years. Many clinical trials...
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A review on the effect of garlic on diabetes, BDNF, and VEGF as a potential treatment for diabetic retinopathy
BackgroundGarlic is one of the favorite herbs in traditional medicine that has been reported to have many medicinal features. The aim of the current...
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Systematic review and meta-analysis of the effect of garlic in patients with non-alcoholic fatty liver disease
BackgroundWe aimed to conduct a systematic review and meta-analyses to examine the therapeutic effect of garlic on non-alcoholic fatty liver disease...
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Catechin, epicatechin, curcumin, garlic, pomegranate peel and neem extracts of Indian origin showed enhanced anti-inflammatory potential in human primary acute and chronic wound derived fibroblasts by decreasing TGF-β and TNF-α expression
BackgroundAlthough chronic wounds are devastating and can cause burden at multiple levels, chronic wound research is still far behind. Chronic wound...
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Effects of garlic (Allium sativum L) and Citrullus colocynthis (L.) Schrad individually and in combination on male reproductive damage due to diabetes: suppression of the AGEs/RAGE/Nox-4 signaling pathway
BackgroundDiabetes Mellitus is associated with disturbances in male reproductive function and fertility. Studies have shown that oxidative stress...
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Effects of garlic and lemon essential oils on performance, digestibility, plasma metabolite, and intestinal health in broilers under environmental heat stress
BackgroundNatural feed additives play an important role in poultry production due to their safety and potential properties as an antioxidant and...
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L-arginine and aged garlic extract for the prevention of migraine: a study protocol for a randomised, double-blind, placebo-controlled, phase-II trial (LARGE trial)
BackgroundMigraine is a common and distressing neurological condition characterised by recurrent throbbing headaches, nausea and heightened...
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Aged garlic extract preserves beta-cell functioning via modulation of nuclear factor kappa-B (NF-κB)/Toll-like receptor (TLR)-4 and sarco endoplasmic reticulum calcium ATPase (SERCA)/Ca2+ in diabetes mellitus
BackgroundPeripheral insulin resistance and compromised insulin secretion from pancreatic β-cells are significant factors and pathogenic hallmarks of...
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Modulatory effects of R10 fraction of garlic (Allium sativum L.) on hormonal levels, T cell polarization, and fertility-related genes in mice model of polycystic ovarian syndrome
Polycystic ovary syndrome (PCOS) is an inflammatory endocrine-metabolic disorder related to reproductive system characterized by polycystic ovarian...
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Attenuation of chronic tension headache frequency and severity with daily l-arginine and aged garlic extract dietary supplementation
A 74-year-old female subject with suboptimal management of episodic tension headache was treated with a daily dose of 1.5 g l -arginine and 1.2 g aged...
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Garlic (Allium sativum L.): a potential unique therapeutic food rich in organosulfur and flavonoid compounds to fight with COVID-19
Coronavirus disease 2019 (COVID-19) is the current major health crisis in the world. A successful strategy to combat the COVID-19 pandemic is the...
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Insight into the intestinal microbiome of farrowing sows following the administration of garlic (Allium sativum) extract and probiotic bacteria cultures under farming conditions
BackgroundDue to the tendency to reduce antibiotic use in humans and animals, more attention is paid to feed additives as their replacement. Crucial...
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Cardioprotective effect of garlic extract in isoproterenol-induced myocardial infarction in a rat model: assessment of pro-apoptotic caspase-3 gene expression
BackgroundMyocardial Infarction (MI), also known as heart attack, is one of the most common cardiovascular diseases. Although certain drugs or...
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The influence of plant extracts on viability of ST3 and ST7 subtypes of Blastocystis sp.
Blastocystis sp. is one of the most frequently detected protozoa during stool specimen examination. In the last decade, the studies about the...
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Purple onion in combination with garlic exerts better ameliorative effects on selected biomarkers in high-sucrose diet-fed fruit fly (Drosophila melanogaster)
Garlic and purple onion are two vegetables widely used globally for culinary purposes. These vegetables have been previously reported to exhibit...
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Cordycepin alleviates osteoarthritis by inhibiting chondrocyte ferroptosis via Keap1/Nrf2 axis
BackgroundIntervertebral disc degeneration (IVDD) is a prevalent condition known to contribute to lower back pain and various spinal disorders. The...
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Evaluation of structural changes of Echinococcus granulosus protoscoleces following exposure to different protoscolicidal solutions evaluated by differential interference contrast microscopy
The present study was aimed to assess the structural changes in protoscoleces of Echinococcus granulosus sensu stricto following exposure to...
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Raw garlic consumption is inversely associated with prehypertension in a large-scale adult population
Previous studies have shown that allicin can lower blood pressure (BP) by reducing oxidative stress and inflammation. However, the association...
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Supplements for Lipid Lowering: What Does the Evidence Show?
PurposeIn this review, the regulation, proposed hypolipidemic mechanism, and efficacy of common dietary supplements (DSs) marketed for cardiovascular...
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The effect of aged garlic extract on the atherosclerotic process – a randomized double-blind placebo-controlled trial
BackgroundOne of the most serious secondary manifestations of Cardiovascular Disease (CVD) is coronary atherosclerosis. This study aimed to evaluate...
