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Pharmacological Treatment of GHB Withdrawal Syndrome
Purpose of ReviewGamma-hydroxybutyrate (GHB) is an illicit drug used for many reasons: during music festivals or parties, for self-management of...
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Alcohol use disorder with comorbid anxiety disorder: a case report and focused literature review
BackgroundAlcohol use disorder (AUD) and anxiety disorders (AnxD) are prevalent health concerns in clinical practice which frequently co-occur...
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Changes in metabolic and hormonal profiles during transition period in dairy cattle – the role of spexin
BackgroundThis study aimed to evaluate spexin as a novel blood marker and to describe the relationship of this peptide with selected biochemical...
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Neurophysiological signature of gamma-hydroxybutyrate augmented sleep in male healthy volunteers may reflect biomimetic sleep enhancement: a randomized controlled trial
Gamma-hydroxybutyrate (GHB) is an endogenous GHB/GABA B receptor agonist, which has demonstrated potency in consolidating sleep and reducing excessive...
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Understandings, attitudes, practices and responses to GHB overdose among GHB consumers
BackgroundGamma-hydroxybutyrate (GHB) is used at disproportionately high rates within sexuality and gender diverse communities and carries a high...
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Predicting the Number of GHB-Related Toxicologic Admissions Using Google Trends Data
In the era of novel psychoactive substances (NPS), the internet became a relevant source of information and purchase for those who consume...
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Der besondere Fall: Koma bei vermeintlicher Alkoholintoxikation
This article reports the case of a 16-year-old male adolescent who needed intensive care as a result of unconsciousness (Glasgow coma scale 3) and...
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Exploring the causal association between serum metabolites and erectile dysfunction: a bidirectional Mendelian randomisation study
Erectile dysfunction is a common sexual disorder in men. Some studies have found a strong association between some serum metabolites and erectile...
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Pregnancy toxemia in Rembi ewe: a case report
Pregnancy toxemia is one of the most common metabolic disorders in ewes. Widely appearing during the late stage of gestation when there is an...
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Salivary metabolites as potential predictive biomarkers for lung surgery complications: a retrospective cross-sectional study
PurposeSaliva is often used as a tool for identifying systemic diseases because of the noninvasive nature of its collection. Moreover, salivary...
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Coordinated Metabolic Responses Facilitate Cardiac Growth in Pregnancy and Exercise
Purpose of ReviewPregnancy and exercise are systemic stressors that promote physiological growth of the heart in response to repetitive volume...
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Substance-Induced Psychosis: a Narrative Review
Purpose of ReviewNovel integrative reviews that give detail information regarding various psychoactive substances (PS) with ability of inducing...
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Cerebrospinal fluid metabolomes of treatment-resistant depression subtypes and ketamine response: a pilot study
Depression is a disorder with variable presentation. Selecting treatments and dose-finding is, therefore, challenging and time-consuming. In...
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Serum mAST/ALT ratio had high predictive value for adverse outcome of severe fever with thrombocytopenia syndrome with severe condition
BackgroundSevere fever with thrombocytopenia syndrome (SFTS) usually demonstrates multi-organ injury with a high mortality rate. This study aimed to...
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Baclofen to Prevent Relapse in Gamma-Hydroxybutyrate (GHB)-Dependent Patients: A Multicentre, Open-Label, Non-Randomized, Controlled Trial
BackgroundGamma-hydroxybutyrate (GHB) dependence is associated with a severe, potentially lethal, withdrawal syndrome and relapse rates as high as...
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HIV Treatment Optimism Moderates the Relationship between Sexual Risk Behavior and HIV Risk Perception among Urban HIV-negative Gay, Bisexual, and Other Men who have Sex With Men
Using baseline data of the Engage Cohort Study, a Canadian study of sexually active gay, bisexual and other men who have sex with men (GBM), we...