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Microfluidic-based production of [68Ga]Ga-FAPI-46 and [68Ga]Ga-DOTA-TOC using the cassette-based iMiDEV™ microfluidic radiosynthesizer
BackgroundThe demand for 68 Ga-labeled radiotracers has significantly increased in the past decade, driven by the development of diversified imaging...
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A head-to-head comparison of [68Ga]Ga-DOTATATE and [68Ga]Ga-FAPI PET/CT in patients with nasopharyngeal carcinoma: a single-center, prospective study
PurposeWe aimed to compare the staging efficiency of [ 68 Ga]Ga-DOTATATE and [ 68 Ga]Ga-FAPI PET/CT in nasopharyngeal carcinoma (NPC) patients.
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Total-body [68 Ga]Ga-PSMA-11 PET/CT improves detection rate compared with conventional [68 Ga]Ga-PSMA-11 PET/CT in patients with biochemical recurrent prostate cancer
PurposeThe purpose of this study was to assess whether total-body [ 68 Ga]Ga-PSMA-11 PET/CT could improve the detection rate compared with...
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[68Ga]Ga-FAPI-04 PET/MR imaging strategy in management of Krukenberg tumors (KTs) from gastric signet-ring-cell carcinoma: to overcome limitation of [68Ga]Ga-FAPI-04 PET imaging in KTs
PurposeTo compare performance of whole-body [ 68 Ga]Ga-FAPI-04 and [ 18 F]FDG PET imaging in the detection of Krukenberg tumors (KTs), primary site and...
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[68Ga]Ga‑LNC1007 PET/CT in the evaluation of renal cell carcinoma: comparison with 2-[18F]FDG/[68Ga]Ga-PSMA PET/CT
PurposeTo compare the potential efficiency of [ 68 Ga]Ga-LNC1007 with 2-[ 18 F]FDG/[ 68 Ga]Ga-PSMA PET/CT for detecting renal cell carcinoma (RCC) and to...
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A prospective comparative study of [68Ga]Ga-RM26 and [68Ga]Ga-PSMA-617 PET/CT imaging in suspicious prostate cancer
PurposeProstate-specific membrane antigen (PSMA)–based PET/CT imaging has limitations in the diagnosis of prostate cancer (PCa). We recruited 207...
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A prospective head-to-head comparison of [68Ga]Ga-P16-093 and [68Ga]Ga-PSMA-11 PET/CT in patients with primary prostate cancer
PurposeWe aimed to compare the diagnostic performance and biodistribution of two similar PET agents, [ 68 Ga]Ga-P16-093 and [ 68 Ga]Ga-PSMA-11, in the...
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Clinical translation of a novel FAPI dimer [68Ga]Ga-LNC1013
AbstractFibroblast activation protein (FAP) has emerged as a highly promising target for cancer diagnostic imaging and targeted radionuclide therapy....
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Diagnostic accuracy of fully hybrid [68Ga]Ga-PSMA-11 PET/MRI and [68Ga]Ga-RM2 PET/MRI in patients with biochemically recurrent prostate cancer: a prospective single-center phase II clinical trial
PurposeTo compare the diagnostic accuracy and detection rates of PET/MRI with [ 68 Ga]Ga-PSMA-11 and [ 68 Ga]Ga-M2 in patients with biochemical...
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The superior detection rate of total-body [68Ga]Ga-PSMA-11 PET/CT compared to short axial field-of-view [68Ga]Ga-PSMA-11 PET/CT for early recurrent prostate cancer patients with PSA < 0.2 ng/mL after radical prostatectomy
Background and purpose[ 68 Ga]Ga-PSMA PET imaging has been extensively utilized for the detection of biochemical recurrence (BCR) in prostate cancer....
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Altered biodistribution of [68Ga]Ga-DOTA-TOC during somatostatin analogue treatment
PurposeThe need for an interval between the administration of long-acting Somatostatin Receptor Analogues (SSA) and the [ 68 Ga]Ga-DOTA-TATE PET has...
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Assessing dynamic metabolic heterogeneity in prostate cancer patients via total-body [68Ga]Ga-PSMA-11 PET/CT imaging: quantitative analysis of [68Ga]Ga-PSMA-11 uptake in pathological lesions and normal organs
PurposeThis study aimed to quantitatively assess [ 68 Ga]Ga-PSMA-11 uptake in pathological lesions and normal organs in prostate cancer using the...
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Total-body PET/CT with half-dose [68 Ga]Ga-PSMA-11 for biochemical recurrent prostate cancer: comparable diagnostic value to short axial field-of-view PET/CT with full-dose [68 Ga]Ga-PSMA-11
PurposeThe objective of this study was to evaluate the diagnostic performance and image quality of total-body positron emission tomography/computed...
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[68Ga]Ga-FAPI-46 PET/CT for penile cancer – a feasibility study
PurposePenile cancer is a rare entity and has a good prognosis in localized stage. Delayed surgical treatment of lymphatic disease is associated with...
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Early detection of anthracycline-induced cardiotoxicity using [68 Ga]Ga-FAPI-04 imaging
PurposeAnthracycline-induced cardiotoxicity (AIC), whose major manifestation is diffuse myocardial fibrosis, is an important clinical problem in...
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Retrospective analysis of thyroid incidentalomas detected by [68Ga]Ga-PSMA-11 PET/CT
BackgroundProstate cancer patients, undergo imaging procedures, with [ 68 Ga]Ga-PSMA-11 PET/CT (prostate-specific membrane antigen based positron...
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Automated radiolabelling of [68Ga]Ga-PSMA-11 (gallium (68Ga)-gozetotide) using the Locametz® kit and two generators
BackgroundSteps have been taken by pharmaceutical companies to obtain marketing authorisation of PSMA ligands in the European Union. Since December...
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Fully automated radiosynthesis of [68Ga]Ga-FAPI-46 with cyclotron produced gallium
BackgroundRadiopharmaceuticals capable of targeting the fibroblast activation protein have become widely utilized in the research realm as well as...
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Diagnostic efficacy of [68Ga]Ga-NY104 PET/CT to identify clear cell renal cell carcinoma
PurposeMost clear cell renal cell carcinoma (ccRCC) overexpresses carbonic anhydrase IX (CAIX). [ 68 Ga]Ga-NY104 is a small-molecule PET agent...
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The clinical signification and application value of [68Ga]Ga-PSMA imaging in thyroid malignancy
PurposeApproximately 5% of differentiated thyroid cancers lose the ability to uptake iodine, leading to limited treatment options and poor prognosis...
